- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Epigenetics and DNA Methylation
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Genetic factors in colorectal cancer
- Genetic Syndromes and Imprinting
- Traffic control and management
- Traffic Prediction and Management Techniques
- IPv6, Mobility, Handover, Networks, Security
- Heavy metals in environment
- Lung Cancer Research Studies
- Transportation Planning and Optimization
- Chromatin Remodeling and Cancer
- Vitamin D Research Studies
- Breast Cancer Treatment Studies
- Protist diversity and phylogeny
- Coal and Its By-products
- Multiple and Secondary Primary Cancers
- Ovarian cancer diagnosis and treatment
- Head and Neck Anomalies
- Advancements in Transdermal Drug Delivery
- Metastasis and carcinoma case studies
- Mine drainage and remediation techniques
- Renal cell carcinoma treatment
Chinese PLA General Hospital
2024
University of South China
2024
Hunan Cancer Hospital
2024
Central South University
2014-2024
Tsinghua University
2006-2023
University of Electronic Science and Technology of China
2022
National University of Defense Technology
2021
NorthShore University HealthSystem
2018-2020
Tianjin Medical University
2010-2015
UCLA Medical Center
2015
Abstract Aims We previously showed that the nab-paclitaxel plus S-1 (NPS) regimen had promising effects against metastatic pancreatic ducal adenocarcinoma (mPDAC), whose efficacy however could not be precisely predicted by routine biomarkers. This prospective study aimed to investigate values of mutations in circulating tumor DNA (ctDNA) and their dynamic changes predicting response mPDAC NPS chemotherapy. Methods Paired tissue blood samples were prospectively collected from patients with...
Abstract Sinomenine is an anti‐rheumatoid arthritis (RA) drug derived from the Sinomenium acutum. The major site of RA treatment within synovial compartment. However, pharmacokinetic and penetration into fluid (SF) sinomenine have not been reported. In our study, pharmacokinetics SF systemic electroporation administered were investigated by microdialysis incorporated with HPLC‐MS/MS. went plasma more rapidly higher peak concentration ( C max ) intramuscular injection compared oral...
Travel time estimation is one of the core tasks for development intelligent transportation systems. Most previous works model road segments or intersections separately by learning their spatio-temporal characteristics to estimate travel time. However, due continuous alternations and in a path, dynamic features are supposed be coupled interactive. Therefore, modeling them limits further improvement accuracy estimating To address above problems, novel graph-based deep framework proposed this...
The aim of this study was to the expression Syk gene and methylation in its promoter region lung cancer investigate relationship between silencing DNA cell lines. Real-time PCR immunohistochemistry were used examine specimens from 3 lines 16 patients (tumor tissues adjacent normal tissues). MSP analyze status region. We also investigated role restoring by using a methyltransferase inhibitor, 5-aza-CdR, suppressing invasion No detected In patient samples, significantly lower tumor than that...
Background The second-line treatment of neuroendocrine tumors (NETs) unknown primary origin remains uncertain. This report presented a patient who received octreotide plus IBI-318 anlotinib as for multiple metastatic NETs lesions after the failure everolimus. Case presentation A 32-year-old male with elevated CEA (197.83 ng/ml) without specific symptoms. contrast-enhanced computed tomography (CT) scan showed lymph nodes and low-density nodules in liver undetermined nature. right...
This study is aimed at evaluating the feasibility of a screening method for pulmonary adenocarcinoma nodules through surface-enhanced Raman spectroscopy (SERS). Objective. Using SERS to measure serum from and healthy subjects, intraoperative biopsy pathological diagnosis was regarded as gold standard labeling samples. To explore application value in differential nodules, benign healthy, we build machine learning model. Method. We collected 116 samples patients. Radiographically confirmed...
Abstract Background In 2010, a Japanese trial of nonoperative management for papillary thyroid microcarcinomas (PTmC) was published. This study determines if the prevalence in United States has changed and there are predictors this approach. Methods Patients treated PTmC between 2004 2015 National Cancer Data Base were identified. Inclusion criteria were: classic or follicular variant cancer histology, tumor size 1 to 10 mm, cN0 disease no extrathyroidal extension metastatic disease....
This study investigated the effect of Ca(H2PO4)2 on pH, leaching toxicity and speciations soil before after it. Different amounts were added to Pb-contaminated stabilized for 30 days. The changes pH tracked during that period. content Pb in was also determined days stabilization. Results showed didn't change much with addition of-Ca(H2PO4)2. When amount reached 3 wt%, met standard limiting level groundwater class III China. found be mainly affected by water-soluble fraction mild acid-soluble...
Travel time estimation is one of the core tasks for development intelligent transportation systems. Most previous works model road segments or intersections separately by learning their spatio-temporal characteristics to estimate travel time. However, due continuous alternations and in a path, dynamic features are supposed be coupled interactive. Therefore, modeling them limits further improvement accuracy estimating To address above problems, novel graph-based deep framework proposed this...
Describing the dynamics of information dissemination within social networks poses a formidable challenge. Despite multiple endeavors aimed at addressing this issue, only limited number studies have effectively replicated and forecasted evolving course dissemination. In paper, we propose novel model, DM-NAI, which not considers transfer between adjacent users but also takes into account non-adjacent to comprehensively depict process. Extensive experiments are conducted on six datasets predict...
Aim: The administration of nab-paclitaxel/carboplatin (nab-PC) as first-line therapy in patients with advanced non-small-cell lung cancer was efficacious and resulted a significantly improved objective overall response rate (ORR) versus solvent-based PC phase ||| trial.Subgroup analysis showed the squamous histology appeared to be predictive factor nab-paclitaxel treatment.This || trial (NCT01236716; CTONG1002) compared eficacy safety