A5037439819- Inflammatory Myopathies and Dermatomyositis
- Muscle Physiology and Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Muscle and Compartmental Disorders
- Eosinophilic Disorders and Syndromes
- Vitamin D Research Studies
- Systemic Sclerosis and Related Diseases
Jagiellonian University
2023-2025
Idiopathic inflammatory myopathies (IIM) are characterized by chronic inflammation, endothelial dysfunction, and muscle tissue mitochondrial defect, leading to the local oxidative stress response. However, data on its systemic intensity correlation with IIM clinical laboratory characteristics remains scarce. In clinically stable dermatomyositis (n = 18) myositis 38) patients matched controls 50), we measured global response in peripheral blood using a novel coumarin boronic acid (CBA) assay...
Abstract Recent reports have demonstrated that endothelial injury is critical in the pathogenesis of systemic sclerosis (SSc) and associated with increased levels circulating inflammatory biomarkers. This study aims to analyze serum concentrations selected cytokines evaluate their relationship SSc clinics long-term course disease. included 43 patients 24 matched healthy controls. In both groups, we measured related response, such as tumor necrosis factor (TNF)α, interferon (IFN)γ,...