A5100412568- Bone Tumor Diagnosis and Treatments
- Sarcoma Diagnosis and Treatment
- Musculoskeletal synovial abnormalities and treatments
- Oral and Maxillofacial Pathology
- Management of metastatic bone disease
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Soft tissue tumor case studies
- Cancer Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Bone and Joint Diseases
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Angiogenesis and VEGF in Cancer
- Shoulder and Clavicle Injuries
- Osteomyelitis and Bone Disorders Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Bone fractures and treatments
- Medical Imaging Techniques and Applications
- Psoriasis: Treatment and Pathogenesis
- Shoulder Injury and Treatment
- Natural product bioactivities and synthesis
- Trauma Management and Diagnosis
- Silk-based biomaterials and applications
- Radiomics and Machine Learning in Medical Imaging
Tianjin Hospital
2013-2024
Tianjin University
2020
Tianjin Medical University
2017
Chinese PLA General Hospital
2011
Abstract Giant cell tumors of the bone (GCTBs) are commonly diagnosed in Asian populations, usually around knee. Herein, we aimed to determine clinical characteristics, local recurrence rates, and relevant risk factors primary GCTB Univariate multivariate survival analyses were used identify for recurrence. Four hundred ten patients with knee, treated between March 2000 June 2014, recruited from 7 institutions China. The overall rate was 23.4%, but higher aged 20–39 years (28.5%; P = 0.039)....
We aimed to determine the demographic characteristics of giant cell tumor around knee in China.Between March 2000 and June 2014, patients with primary were recruited from 6 institutions located different regions China, reviewed retrospectively clinical features according gender age.334 qualified included this study. The sex ratio was 1.14:1 (178/156), mean ages 36.9 years men 33.1 women, constituting a significant difference (P=0.007). prevalence pathological fracture 32.9% overall (28.7%...
Intralesional excision with curettage is the standard method of giant cell tumor (GCT) treatment, but ideal filling material after remains controversial. The purpose this study was to compare oncological and functional outcomes which underwent cementation or bone grafting GCT around knee.We reported 136 cases GCTs in distal femur proximal tibia who accepted from five clinical centers during last 15 years. All patients were divided into two groups according materials. Recurrence-free survival...
To evaluate the result of en bloc resection and reconstruction distal radius with a non-vascularized fibular autograft for giant cell tumor (GCT) bone.Between 2005 2015, 12 eligible patients (seven males, five females, mean age 31.3 years) grade III GCT were treated by proximal autografts in four Chinese institutions (members Giant Cell Tumor Team China). The had clinical radiographic review every 6 months first 2 years then annually thereafter. functional, oncologic radiological outcomes...
Retrospective clinical and radiologic evaluation.To investigate the feasibility of a 1-stage combined posterior anterior approaches for excising thoracolumbar lumbar tumors with patient lying in lateral position.Traditional anteroposterior total spondylectomy require 2-stage operation or changing patient's position, secondary sterilization one stage. So surgical time, cost trauma, as well blood loss, would be increased. One-stage en bloc position may good way improving it.This study...
Objective To evaluate the correlation between features of knee joint rheumatoid arthritis (RA) identified on MRI and histological examination as a means elucidating pathogenesis destruction in RA. Methods This is prospective analysis 26 joints 22 patients who underwent total arthroplasty (TKA) for treatment Based degree articular cartilage menisci, occurrence bone marrow edema erosion, synovial thickening, stage were classified using by two radiologists. Differences severity medial lateral...
Objective To explore the effect of kartogenin (KGN) on proliferation and chondrogenic differentiation human umbilical cord mesenchymal stem cells (hUCMSC) in vitro , synergistic effects KGN transforming growth factor (TGF)‐β3 hUCMSC. Methods Human were isolated cultured. Then properties identified by flow cytometry analysis. HUCMSC divided into four groups: control group, TGF‐β3 TK group (with added medium simultaneously). Cells all groups induced for 21 days using suspension ball culture...
To investigate the association between number of metastases to spine and survival in patients with metastatic spinal cord compression (MSCC), as well prognosis difference solitary metastasis (SSM) multiple (MSM).Three institutional databases were searched identify all who had undergone surgery for tumors March 2002 June 2010. As age gender, preoperative medical conditions collected from records, including primary tumor, Frankel score, other bone metastases, Karnofsky performance status...
Abstract Although giant cell tumor of bone (GCTB) is more common in women Western countries, it tends to be men Asian countries. We aimed determine the sex differences clinical characteristics, local recurrence rate, and relevant risk factors for primary GCTB around knee. Between March 2000 June 2014, patients with knee were recruited from 7 institutions China, 410 included. The age at diagnosis was younger than (34.0 vs 37.2 years). rates 23.4% overall, 25.8% men, 20.7% women. Lower...
Giant cell tumors of the distal radius are challenging for surgeons because they associated with high recurrence rates and poor functional outcomes. Between June 2005 October 2015, patients primary giant were recruited from seven orthopedic centers in China. The patients' clinical features demographic characteristics obtained medical records reviewed retrospectively. Overall, 48 cases assessed this study. These more likely to be between 20 40 years age, have a Campanacci grade III, undergo...
Background: Chondrosarcoma is a malignant tumor originating from cartilage tissue. It the second most bone tumor, accounting for about 10% to 15% of all primary tumors. So far, there have been no reports large-scale clinical statistics on relationship between non-surgical treatment and prognosis in patients with chondrosarcoma.
Objective: To explore the feasibility and effect of microwave in situ inactivation malignant primary or metastatic tumors scapula. Methods: Seventeen patients (12 men, 5 women, mean age 48 years [range, 13–59 years]) with involving scapula were treated by between June 1998 February 2008. There were12 bone tumors. In 14 cases Area Sl was involved 3 both Areas S1 S2. All 17 making a dorsal arc‐ “∩‐” shaped incision to expose tumor, protecting surrounding soft tissues copper grid, then heated...
The purpose of this study was to discuss the clinical results which related location giant cell tumors (GCTs) in pelvis so as determine ideal surgical treatment protocol. We report 29 cases who accepted from five centers during last 12 years. All patients were divided into three groups according tumor locations, and they also classified two light treatments. parameters for outcome evaluation consisting general condition, complications, local disease control, Musculoskeletal Tumor Society...
Objective To compare the clinical outcomes of microwave-assisted intralesional curettage(MAIC) with those en bloc resection and autogenous fibular reconstruction (EBR-AFR) for treating grade III giant cell tumor bone (GCTB) distal radius to elucidate indications wrist preservation surgery. Materials methods In this retrospective study, 19 patients GCTB who underwent surgery at three medical institutions were included categorized based on their surgical pattern. Seven MAIC internal fixation...
The aim of the present study was to characterize morphological parameters giant cell tumor bone (GCTB) in knee. imaging data 250 patients with GCTB knee were retrospectively reviewed, and analyzed. included 137 cases distal femur 113 proximal tibia. maximal longitudinal diameter 6.616±2.322 cm group 5.738±2.278 tibia (P=0.003). transverse two groups 4.865±1.525 4.313±1.309 cm, respectively shortest distance from articular surface (SDAS) 0.381±0.404 0.280±0.328 (P=0.035), whereas longest...
Giant cell tumour of bone is one the most common primary musculoskeletal tumours, accounting for 10%-21% bengin which can behave like malignant tumors and have benign histologic characteristics. (GCT) classified by World Health Organisation (WHO) as a but locally aggressive tumour. Intralesional excision wide resection may be helpful in operative treatment GCT. However, there are limitations with these options spite use adjuvant therapy. For instance, intralesional had more local recurrence...