A5019359872- Geochemistry and Geologic Mapping
- Ginseng Biological Effects and Applications
- Chromatography in Natural Products
- Traditional Chinese Medicine Analysis
- Geological and Geochemical Analysis
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Metabolomics and Mass Spectrometry Studies
- Prenatal Screening and Diagnostics
- Geochemistry and Geochronology of Asian Mineral Deposits
- Soil Geostatistics and Mapping
- Environmental Quality and Pollution
- Hydrocarbon exploration and reservoir analysis
- Geographic Information Systems Studies
- earthquake and tectonic studies
- Medicinal Plant Pharmacodynamics Research
- Traditional Chinese Medicine Studies
- Plant biochemistry and biosynthesis
- Phytochemistry and Bioactivity Studies
- Fetal and Pediatric Neurological Disorders
- Phytochemical compounds biological activities
- Geochemistry and Elemental Analysis
- Food Quality and Safety Studies
- Plant Gene Expression Analysis
Nanjing University of Chinese Medicine
2017-2025
Anhui Normal University
2023-2025
Chengdu University of Technology
2010-2024
Guangxi Medical University
2024
First Affiliated Hospital of GuangXi Medical University
2024
First Affiliated Hospital of Guangdong Pharmaceutical University
2022
Guangdong Pharmaceutical University
2022
Ministry of Natural Resources
2020
Shanghai Innovative Research Center of Traditional Chinese Medicine
2020
Nanfang Hospital
2005-2019
Eucommia ulmoides Oilv. (EU), also called Du-zhong, is a classical traditional Chinese medicine. Its bark, leaf, and male flower are all used for medicinal purposes, Eucommiae Cortex (EC), Folium (EF), Flos Male (EFM). In order to study the difference in synthesis accumulation of metabolites different parts EU, reliable method based on ultra-fast liquid chromatography tandem triple quadrupole mass spectrometry (UFLC-QTRAP-MS/MS) was developed simultaneous determination total 21 constituents,...
Licorice (Glycyrrhiza uralensis Fisch) possesses a substantial share of the global markets for its unique sweet flavor and diverse pharmacological compounds. Cultivated licorice is widely distributed in northwest regions China, covered with land broad range salinities. A preliminary study indicated that suitable salt stress significantly increased content bioactive constituents licorice. However, molecular mechanisms underlying influence salinity on accumulation these remain unclear, which...
Xijiao Dihuang Tang (XDT), a classic TCM prescription, has been used to clinically treat blood-heat and blood-stasis syndrome- (BHSS-) related diseases, including hemorrhagic stroke sepsis. However, the active constituents mechanism of XDT in treatment BHSS-related diseases have not elucidated due lack appropriate methodologies. In this study, serum pharmacochemistry network pharmacology were explore diseases. The effects evaluated using dry yeast-induced rats as rat models with BHSS, which...
Abstract Spica Prunellae is an important Chinese herbal medicine. Because of its good curative effect on various diseases, this herb consumed in large quantities clinical applications. The metabolites are known to change under salt stress; however, the difference protein levels between saline and normal conditions unclear. In study, we used proteomics techniques identify differentially expressed proteins different conditions. (iTRAQ) MS/MS was detect statistically significant changes stress...
As one of the major abiotic stresses, salinity stress may affect physiology and biochemical components Apocynum venetum L. To systematically evaluate quality Apocyni Veneti Folium (AVF) from perspective physiological wide variety bioactive response to various concentrations salt stress, this experiment was arranged on basis ultra-fast liquid chromatography tandem triple quadrupole mass spectrometry (UFLC-QTRAP-MS/MS) technology multivariate statistical analysis. Physiological characteristics...
Lonicerae Japonicae Flos (LJF) and (LF) belong to different genera of Caprifoliaceae. They have been historically utilised as herbal medicine treat various diseases. However, the comprehensive assessment them still remains a challenge.To develop method ultra-fast liquid chromatography-tandem triple quadrupole mass spectrometry (UFLC-QTRAP-MS/MS) coupled with multivariate statistical analysis for quality evaluation reveal differential components LJF LF.A validated UFLC-QTRAP-MS/MS was...
Salinity stress significantly affects the contents of bioactive constituents in licorice Glycyrrhiza uralensis. To elucidate molecular mechanism underlying difference accumulation these under sodium chloride (NaCl, salt) stress, seedlings were treated with NaCl and then subjected to an integrated transcriptomic metabolite profiling analysis. The analysis results identified 3,664 differentially expressed genes (DEGs) including transcription factor family MYB basic helix-loop-helix (bHLH)....
A novel homogeneous fluorescence assay strategy for highly sensitive detection of thymine DNA glycosylase (TDG) enzyme activity based on the exonuclease-mediated signal amplification reaction was reported.
Ginseng effectively reduces fatigue in both animal models and clinical trials. However, the mechanism of action is not completely understood, its molecular targets remain largely unknown.By screening for proteins that interact with primary components ginseng (ginsenosides) an affinity chromatography assay, we have identified muscle-type creatine kinase (CK-MM) as a potential target skeletal muscle tissues.Biolayer interferometry analysis showed ginsenoside metabolites, instead parent...
In this study, a fingerprint-activity relationship modeling between chemical fingerprints and antirheumatic activity was established, multivariate statistical analysis used to evaluate the quality of Taxilli Herba (TH) from different hosts. Characteristic 20 batches TH samples were generated by high-performance liquid chromatography coupled with triple quadrupole-time flight tandem mass spectrometry (HPLC-Triple TOF-MS/MS), similarity calculated based on thirteen common characteristic peaks...
The thin but widely distributed sandstones in the shallow-water deltas have potential to hold large deposits of natural gas. fluvial sand bodies formed from river channels with different sedimentary facies and sandstone architectures remarkable heterogeneities. results this investigation suggest that a significant impact on hydrocarbon accumulation production reservoirs. Information regarding origin architecture deltas, especially fingered bar type, is still very limited. This focused...