Eucommia ulmoides Oilv. (EU), also called Du-zhong, is a classical traditional Chinese medicine. Its bark, leaf, and male flower are all used for medicinal purposes, Eucommiae Cortex (EC), Folium (EF), Flos Male (EFM). In order to study the difference in synthesis accumulation of metabolites different parts EU, reliable method based on ultra-fast liquid chromatography tandem triple quadrupole mass spectrometry (UFLC-QTRAP-MS/MS) was developed simultaneous determination total 21 constituents,...

Abstract Spica Prunellae is an important Chinese herbal medicine. Because of its good curative effect on various diseases, this herb consumed in large quantities clinical applications. The metabolites are known to change under salt stress; however, the difference protein levels between saline and normal conditions unclear. In study, we used proteomics techniques identify differentially expressed proteins different conditions. (iTRAQ) MS/MS was detect statistically significant changes stress...

Abstract Hydrothermal reactions of 1, 2, 4‐benzenetricarboxylic acid, 10‐phenanthroline and transition metal cations including Zn II or Co , in basified aqueous solution gave rise to two complexes, [Zn 3 (btrc) 2 (1, 10‐phen) (H O) ] n ( 1 ), [Co ) (btrc = 4‐benzenetricarboxylate, 10‐phen 10‐phenanthroline). crystalize isotypically the triclinic space group P1¯. The btrc ligand acts as multi‐dentate bridging both compound link up atoms into lamella networks, which are further attached...

Pseudostellariae Radix (PR) is an important traditional Chinese herbal medicine (TCM) with vast clinical consumption because of its positive effects. However, little attention has been devoted to simultaneous analysis bioactive components for quality control PR based on different harvesting times, growing habitats, and processing methods. In this research, the was evaluated determination multiple combined grey relational (GRA). A reliable method ultra-fast liquid chromatography tandem triple...

The hydrothermal reactions of 1,2,4-benzenetricarboxylate (H3btrc), 4,4'-bipyridine (4,4'-bpy), or 1,10-phenanthroline (1,10-phen) with transition metal acetates in basified solvent gave rise to three novel coordination polymers, [Ni3(btrc)2(4,4'-bpy)2(H2O)5]n·2nH2O (1), [Cu3(btrc)2(1,10-phen)3]n (2), and [Co(H2btrc)2(4,4'-bpy)3(H2O)2]n (3), which show respectively three-dimensional polymeric architecture, two-dimensional lamella, one-dimensional chain architecture. Interestingly, the...

Scrophulariae Radix is one of the most popular traditional Chinese medicines (TCMs), which needs to be processed by 'sweating' methods. Primary processing an important link closely relates quality products in this TCM. To facilitate selection suitable method for Radix, study different methods was evaluated based on simultaneous determination multiple bioactive constituents combined with grey relational analysis. The contents iridoid glycosides, phenylpropanoid and organic acids were...

Scrophulariae Radix is one of the most popular traditional Chinese medicines. The harvesting time closely related to quality products in this medicine. goal study analyze dynamic changes metabolite accumulation Radix. difference constituents harvested at different times was analyzed by liquid chromatography with triple quadrupole-time flight tandem mass spectrometry coupled principal component analysis and partial least-square discriminant analysis. According accurate molecular product ions...

Apocyni Veneti Folium (AVF) is a kind of staple traditional Chinese medicine with vast clinical consumption because its positive effects. However, due to the habitats and adulterants, quality uneven. To control this medicinal herb, in study, AVF was evaluated based on simultaneous determination multiple bioactive constituents combined multivariate statistical analysis. A reliable method ultra-fast liquid chromatography tandem triple quadrupole mass spectrometry (UFLC-QTRAP-MS/MS) developed...

Scrophulariae Radix is one of the most popular traditional Chinese medicines (TCMs). Primary processing an important link which closely related to quality products in this TCM. The aim study explore influence different methods on chemical constituents Radix. difference processed by was analyzed using ultra fast liquid chromatography-triple quadrupole-time flight mass spectrometry coupled with principal component analysis and orthogonal partial least squares discriminant analysis....

Abstract In this study, a fingerprint-activity relationship between chemical fingerprints and hepatoprotective activity was established to evaluate the quality of salt-treated Apocyni Veneti Folium (AVF). Characteristic AVF samples exposed different concentrations salt were generated by ultrafast liquid chromatography tandem triple time-of-flight mass/mass spectrometry (UFLC-Triple TOF-MS/MS), similarity analysis performed based on common characteristic peaks hierarchical clustering (HCA)....

Abstract Eucommiae Cortex is a classical traditional Chinese medicine, which needs to be processed by “sweating” methods. To select the suitable processing method and condition for Cortex, in this study, quality of was evaluated based on simultaneous determination multiple bioactive constituents combined with gray relational analysis. The contents lignans, iridoids, penylpropanoids, flavonoids, phenols samples were simultaneously determined using ultra‐fast performance liquid chromatography...

Abstract Site‐specific accumulation of flavonoids in Apocyni Veneti Folium was determined by laser scanning confocal microscope (LSCM) and the localization catechins also observed via vanillin ‐HCl staining under conventional optical microscope. The contents five from different harvest times growth parts were measured using HPLC method. LSCM observation showed that are accumulated cuticle epidermal cells vessel walls, especially protoplasts nucleolus collenchyma cells. Catechins localized...

Magnoliae Officinalis Cortex (MOC) is a commonly used traditional Chinese herbal medicine, which always preliminarily processed by “sweating”. To explore the effects of primary processing on chemical constituents in MOC and potential markers for differentiating samples “sweating” “non sweating”, method proposed based ultra fast liquid chromatography-triple quadrupole-time flight mass spectrometry (UFLC-Triple TOF MS/MS) gas quadrupole (GC-MS/MS) coupled with multivariate statistical...

Abstract Hydrothermal reactions of NaN 3 , 1, 10‐phenanthroline or 2, 2′‐bipyridine and transition metal cations including Zn II Co in basified aqueous solutions yielded the three complexes, [Zn 2 (bipy) (N ) 4 ] n ( 1 ), [Zn(phen)(N [Co(phen) which were characterized by X‐ray crystallography. All complexes crystallize triclinic system, space group P1¯, with a = 6.5506(2), b 10.8441(6), c 16.893(2)Å, α 96.333(5), β 95.361(7), γ 90.548(6)° for ; 7.0302(10), 10.0590(14), 10.4550(15)Å,...

In order to study the influence of ecological environment regarding synthesis and accumulation metabolites in Eucommiae Cortex, LC-QTOF MS/MS method combined with multivariate statistical analysis was used analyze differences chemical constituents Cortex from different habitats. Through multistage tandem mass spectrometry, characteristic peaks were extracted spectrometry data peak matching, alignment, noise filtering. Principal component (PCA) partial least-squares discriminant (PLS-DA) for...

The interaction between two partially methyl-substituted cucurbiturils, a sym-tetramethyl-substituted cucurbit[6]uril (TMeQ[6]) and meta-hexamethyl-substituted cucurbituril (m-HMeQ[6]), with the hydrochloride salt of benzidine (g1·HCl) analogue bis(4-aminophenyl) methane (g2·HCl) was investigated by single crystal X-ray diffraction determination, 1H NMR spectroscopy, electronic absorption spectroscopy fluorescence spectroscopy. Single determination showed guest compounds were excluded at...

This article using mutative scale chaos genetic algorithm (MSCGA) in load distribution calculation of hot strip mill finishing rolling unit, Visual C++ 6.0 developed set computing system software platform. It can achieve test (positive algorithm) field experience (mechanism) reasonable, inverse amendment, MSCGA optimization (manually and automated), device technical parameters on-line adjustment, etcetera. The has good people-machine interface provides easy operation. fast operation speed to...