A5101971990- Ubiquitin and proteasome pathways
- Image and Signal Denoising Methods
- Mathematical Analysis and Transform Methods
- Sparse and Compressive Sensing Techniques
- Perovskite Materials and Applications
- Enzyme Production and Characterization
- Peptidase Inhibition and Analysis
- Blind Source Separation Techniques
- Embedded Systems and FPGA Design
- Plant tissue culture and regeneration
- Analytical Chemistry and Chromatography
- Power Systems and Technologies
- Plant Reproductive Biology
- Phytase and its Applications
- Higher Education and Teaching Methods
- Video Surveillance and Tracking Methods
- Plant Molecular Biology Research
- Multi-Agent Systems and Negotiation
- Advanced Computational Techniques and Applications
- Anomaly Detection Techniques and Applications
- Spectroscopy and Chemometric Analyses
- Microbial Natural Products and Biosynthesis
- Pomegranate: compositions and health benefits
- Medicinal Plants and Bioactive Compounds
- Phytochemistry and Bioactive Compounds
Wuhan National Laboratory for Optoelectronics
2024-2025
Huazhong University of Science and Technology
2016-2025
China Automotive Technology and Research Center
2024
First Hospital of Jilin University
2023
Jilin University
2023
University of Electronic Science and Technology of China
2008-2022
Zhejiang Chinese Medical University
2022
First Affiliated Hospital of Anhui Medical University
2021
Anhui Medical University
2021
South China Agricultural University
2019-2020
Callose plays an important role in pollen development flowering plants. In rice, 10 genes encoding putative callose synthases have been identified; however, none of them has functionally characterized. this study, a rice Glucan Synthase-Like 5 ( GSL5 ) knock-out mutant was isolated that exhibited severe reduction fertility. Pollen viability tests indicated the abnormal while embryo sac normal. Further, -RNA interference transgenic plants phenocopied gsl5 mutant. The RNA expression found to...
The earthworm fibrinolytic enzyme (EFE) is a complex protein that widely distributed in the earthworm's digestive cavity. Possessing strong hydrolysis activity, EFE not only has direct effect on fibrin, but also can activate plasminogen. Its therapeutic and preventative effects thrombosis-related disease have been confirmed clinically. Recently, there increased interest anti-tumor activity of EFE. In this study, EFE, isolated from Eisenia foetida, human hepatoma cells was evaluated vitro...
FACT plays important roles in both gene transcription and DNA replication. However, how this protein complex is targeted to these two distinct cellular processes remains largely unknown. Here we show that ubiquitylation of the Spt16 subunit by Rtt101, cullin an E3 ubiquitin ligase Saccharomyces cerevisiae , links We find Rtt101 interacts with ubiquitylates vitro vivo. Deletion RTT101 leads reduced association replicative helicase MCM replication origins. Loss also reduces binding MCM, but...
Summary Environment‐sensitive genic male sterility (EGMS) lines are used widely in two‐line hybrid breeding rice ( Oryza sativa ). At present, photoperiod‐sensitive (PGMS) and thermo‐sensitive (TGMS) predominantly rice, with humidity‐sensitive (HGMS) rarely being reported. Here, it is shown that HUMIDITY‐SENSITIVE GENIC MALE STERILITY 1 HMS1 ), encoding a β‐ketoacyl‐CoA synthase, plays key roles the biosynthesis of very‐long‐chain fatty acids (VLCFAs) HGMS rice. The hms1 mutant displayed...
Abstract Organic–inorganic hybrid perovskite is emerging as one of the most promising light source technologies. Various interfacial agents have been widely used on surfaces, aiming to achieve high brightness and stability in light‐emitting diodes (PeLEDs) by eliminating adverse effects excess organic halide residues. However, there are only scattered reports available unreacted distribution, solvent effect, cost‐performance for surface engineering, calling low‐cost strategies address these...
Proteasomes can be markedly activated by associating with 19S regulatory complexes to form the 26S protease or binding 11S protein known as REG PA28. Three subunits, α, β, and γ, have been expressed in Escherichia coli , each recombinant activate human proteasomes. Combining PCR mutagenesis an vitro activity assay, we isolated characterized 36 inactive, single-site mutants of REGα. Most are monomers that produce functional proteasome activators when mixed REGβ subunits. Five REGα remain...
Abstract Ubiquitination, an essential post-transcriptional modification (PTM), plays a vital role in nearly every biological process, including development and growth. Despite its functions plant reproductive development, targets rice panicles remain unclear. In this study, we used proteome-wide profiling of lysine ubiquitination (O. sativa ssp. indica) young panicles. We created the largest ubiquitinome dataset to date, identifying 1638 sites on 916 unique proteins. detected three conserved...
Osteoporosis (OP) is a common skeletal disease, characterized by decreased bone formation and increased resorption. As novel Chinese medicine formula, Zhuanggu Busui formula (ZGBSF) has been proved to be an effective prescription for treating OP in clinic, however, the pharmacological mechanisms underlying beneficial effects remain obscure. In this study, we explored of ZGBSF against via network pharmacology analysis coupled with vivo experimental validation. The results showed that total 86...
Abstract Flexible perovskite solar cells (F‐PSCs) are highly promising for both stationary and mobile applications because of their advantageous features, including mechanical flexibility, lightweight thin nature, cost‐effectiveness. However, a number drawbacks, such as instability, make practical application difficult. Here, self‐welding dynamic diselenide that is triggered by visible light into the structure F‐PSCs to improve long‐term stability repairing cracks defects in absorber layer...
Ovarian cancer (OC) is a common gynecological malignant tumor with poor prognosis. Ferroptosis an iron-dependent modality of regulated cell death. The purpose this study was to determine the prognostic ability ferroptosis-related long non-coding RNAs (lncRNAs) in OC patients and construct lncRNA model.The Cancer Genome Atlas (TCGA) FerrDb databases were used collect RNA sequencing data genes, respectively. randomly assigned training or testing set. Pearson correlation analysis identify...
Due to the high Lewis acidity of Sn2+, it is a major challenge prepare high-quality CsSnI3 films. To solve this critical problem, here we propose pseudohalide anion alloying process regulate crystallization inorganic perovskite and achieve large grain sizes in micron range. The introduction changes phase transition pathways through formation intermediates, thereby slowing rate crystallization. substitutional HCOO– crystal lattice further improves oxidation resistance Sn2+ due strong bonding...
The proteasome 11 S regulator (REG) consists of two homologous subunits, REGα and REGβ. Each subunit is capable activating the proteasome, when combined, they form superactive REGα/REGβ complexes. We have previously shown that a highly conserved loop in crystal structure critical for activation. now show hetero-oligomers formed from activation mutants wild-type REGβ or vice versa are partially active. By contrast, bearing mutations loops subunits inactive, demonstrating both α β contribute...
The present study aimed to assess the changes in circulating microRNA (miRNA) expression profiles associated with potential osteoprotective effect of diosgenin (DIO) ovariectomized (OVX) rats. Wistar rats (female) were subjected a sham operation (SHAM group) or ovariectomy. OVX treated DIO (DIO vehicle (OVX for 12 weeks. Following treatment, serum estradiol, bone turnover biomarker levels, and microarchitecture tibias assayed. Based on miRNA microarray qRT-PCR analyses, differentially...
Security modeling for agents has been one of the most challenging issues in developing practical mobile agent software systems. In past, researchers have developed systems with emphasis either on protecting from malicious hosts or agents. this paper, we propose a security based system architecture that provides general solution to both and terms communication migration. We present facilitator model serves as middleware secure The model, well is agent-oriented G-nets — high level Petri net...