- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Alzheimer's disease research and treatments
- Ferroptosis and cancer prognosis
- GABA and Rice Research
- Medicinal Plants and Neuroprotection
- Biological and pharmacological studies of plants
- Spine and Intervertebral Disc Pathology
- Traditional Chinese Medicine Analysis
- Diabetes, Cardiovascular Risks, and Lipoproteins
- High-Voltage Power Transmission Systems
- Sirtuins and Resveratrol in Medicine
- Power Line Inspection Robots
- Meat and Animal Product Quality
- COVID-19 and Mental Health
- Soft Robotics and Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Blood groups and transfusion
- Body Contouring and Surgery
- Alcoholism and Thiamine Deficiency
- Diabetes Management and Education
- Cell death mechanisms and regulation
- Facial Trauma and Fracture Management
- Vacuum and Plasma Arcs
- Eating Disorders and Behaviors
Pingdingshan University
2024
University of Hong Kong
2024
Johns Hopkins University
2024
Shenzhen University Health Science Center
2024
First Hospital of China Medical University
2023
Shenzhen University
2023
China Medical University
2023
Tongren Hospital
2019-2022
Harbin Medical University
2013-2022
Beijing Friendship Hospital
2022
Abstract The prognostic value of programmed death-ligand 1 (PD-L1) in gastric cancer (GC) remains controversial. To clarify this problem, we performed a meta-analysis research studies identified the PubMed, EMBASE and Cochrane Library databases. A total 1,901 patients 10 were enrolled meta-analysis, pooled hazard ratio (HR) 1.64 (95% CI 1.11 to 2.43; P = 0.01) indicated that PD-L1 expression is associated with shorter overall survival (OS). odds ratios (ORs) was tumour size (OR 1.87, 95%...
Background: Dendrobium nobile Lindl. alkaloids (DNLA) are effective in ameliorating cognitive deficit SAMP8, AβPP/PS1, and LPS-induced AD animal models, prevented Aβ-induced synaptic degeneration cultured hippocampal neurons. However, the underlying mechanisms remain unexplored. Objective: This study investigated protective effects of DNLA on damage an Aβ25-35-induced rat model, primary cortical neuron cultures, PC12 cells transfected with human AβPP695, focusing Wnt/β-catenin pathway....
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Although the prognostic value of programmed cell death-ligand 1 (PD-L1) expression in non-Hodgkin lymphoma (NHL) has been evaluated many studies, results remain controversial. To investigate role PD-L1 and association between clinicopathological features NHL, we performed a meta-analysis.The PubMed, EMBASE, Cochrane Library databases were searched up to November 30, 2017. The hazard ratio (HR), 95% confidence interval (CI), odds ratios (OR) with CIs combined evaluate overall survival (OS)...
Alzheimer's disease (AD) is the primary cause of dementia in elderly. The imbalance between production and clearance amyloid β (Aβ) a very early, often initiating factor AD. Dendrobium nobile Lindl. alkaloids (DNLA) extracted from Chinese medicinal herb, which have been shown to anti-aging effects, protected against neuronal impairment vivo vitro. Moreover, we confirmed that DNLA can improve learning memory function elderly normal mice, indicating has potential health benefits. However,...
The aim of this study was to evaluate whether green tea powder (GTP) addition could affect egg quality and storage. Eggs were collected after 12 weeks feeding from control GTP treatment groups Huainan partridge hens. Egg quality, radical scavenging capacity, albumen viscosity, lysozyme content activity compared between the two during hens supplemented with exhibited higher height, antioxidant viscosity haugh unit lower shell thickness strength when group (p < .05). During storage, eggs...
Background:The prognostic role of PD-L1 expression in surgically resected lung adenocarcinoma (ADC) remains controversial.The present study was aimed to clarify the predicting prognosis and investigate its biological function ADC. Materials Methods:The association between clinical outcomes patients with ADC analyzed using immunohistochemistry (IHC) our cohort (n=104), externally validated by a meta-analysis 13 published studies.The explored gene set enrichment analysis (GSEA).Results:...
Objective: Pei-Yuan-Tong-Nao (PYTN) capsule has been widely used for the treatment of cerebrovascular disease (CVD), including cerebral ischemia. However, due to complexity traditional Chinese Medicine (TCM) and lack proper inspection methods, pharmacological mechanisms actions PYTN on CVD remain ambiguous. In this investigation, a network pharmacology method was investigate mechanism action in CVD. Methods: method, chemical similarity ensemble approach employed predict putative targets...
This study aimed to explore the feasible effect of ezetimibe for postprandial hyperlipidemia (PPHP).Sixty participants were included in this study. Of these, 30 subjects intervention group received ezetimibe, while remaining control did not undergo ezetimibe. All patients treated a total 2 weeks. Primary endpoints consisted serum levels cholesterol (Total-C), low-density lipoprotein (LDL-C), high-density (HDL-C), and triglyceride (TG). Secondary apoB-48, remnant (RLP-C), blood glucose,...
Laminar decompression surgery is the most common operation in spinal surgery, and it also considered to be one of risky difficult operations. In recent years, medical robots have become a hot topic assisting doctors laminar flow grinding operations during surgery. this paper, spine robot system established, kinematics analysis, workspace singularity analysis 6-DOF surgical are carried out. An efficient motion-constrained strategy plan was formulated. order verify feasibility strategy, two...