Lucas Freitas de Freitas

ORCID: 0000-0001-7934-9421
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About
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Research Areas
  • Photodynamic Therapy Research Studies
  • Nanoplatforms for cancer theranostics
  • Fullerene Chemistry and Applications
  • Laser Applications in Dentistry and Medicine
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Medical and Biological Ozone Research
  • Nanoparticle-Based Drug Delivery
  • Nanoparticles: synthesis and applications
  • Radiation Therapy and Dosimetry
  • Photoacoustic and Ultrasonic Imaging
  • Graphene and Nanomaterials Applications
  • Laser-Ablation Synthesis of Nanoparticles
  • Proteins in Food Systems
  • Catalytic Processes in Materials Science
  • QR Code Applications and Technologies
  • Smart Grid Security and Resilience
  • Skin Protection and Aging
  • Bee Products Chemical Analysis
  • Pineapple and bromelain studies
  • Oral microbiology and periodontitis research
  • Electricity Theft Detection Techniques
  • Protein Interaction Studies and Fluorescence Analysis
  • Chemical Reactions and Mechanisms
  • Advanced Nanomaterials in Catalysis
  • Advanced Radiotherapy Techniques

Instituto de Pesquisas Energéticas e Nucleares
2018-2024

National Nuclear Energy Commission
2018-2024

Universidade Presbiteriana Mackenzie
2024

Universidade de São Paulo
2013-2023

Universidade Tecnológica Federal do Paraná
2018-2021

Universidade do Estado do Rio de Janeiro
2020

Instituto de Educação Superior de Brasília
2020

Universidade Federal da Paraíba
2019

Fundação de Amparo à Pesquisa do Estado de São Paulo
2016

Universidade Federal de São Carlos
2016

Photobiomodulation (PBM) also known as low-level laser (or light) therapy (LLLT), has been for almost 50 years but still not gained widespread acceptance, largely due to uncertainty about the molecular, cellular, and tissular mechanisms of action. However, in recent years, much knowledge this area, which will be summarized review. One most important chromophores is cytochrome c oxidase (unit IV mitochondrial respiratory chain), contains both heme copper centers absorbs light into...

10.1109/jstqe.2016.2561201 article EN IEEE Journal of Selected Topics in Quantum Electronics 2016-05-01

This study intended to evaluate the effects of a papain-gel with red-light absorbing pigment (methylene blue - MB) mediate photodynamic therapy (PDT) against Streptococcus mutans biofilms. The PapaMBlue was compared free MB generate reactive oxygen species using fluorescence probes (SOSG and HPF). PDT (660-nm light) carried out S. biofilms grown on either plastic dishes or collagen membrane assayed by CFU, live-dead staining confocal microscopy, transmission electron microscopy H&E for...

10.1038/srep33270 article EN cc-by Scientific Reports 2016-09-19

The aim of the present study was to compare effects strength training (ST) with continuous or intermittent blood flow restriction (BFR) on muscle hypertrophy (MH), dynamic (DMS), isometric (IMS) and localized muscular endurance (LME) healthy men. Twenty-five men experience in ST were randomly divided into 3 experimental groups: a) 4 low-load exercises at 20% one-repetition maximum (1RM) combined BFR (LL+CBFR), b) 1RM (LL+IBFR); c) without (LL). Twelve sessions performed (twice a week for 6...

10.4025/actascihealthsci.v41i1.42273 article EN cc-by Acta Scientiarum Health Sciences 2019-05-22

Extensive research and practical applications have been conducted within the biomaterials domain, focusing on polylactic acid (PLA) based composite.These composites explored for their favorable attributes, such as excellent processability, biodegradability, bioactivity properties, but still lack mechanical properties.In this work, PLA-based nanocomposites were prepared by incorporating hydroxyapatite (HA) graphene oxide (GO) via melt mixing (extruder).Filaments obtained to develop scaffolds...

10.3144/expresspolymlett.2024.48 article EN publisher-specific-oa eXPRESS Polymer Letters 2024-01-01

Recent advancements in nanomedicine and nanotechnology have expanded the scope of multifunctional nanostructures, offering innovative solutions for targeted drug delivery diagnostic agents oncology nuclear medicine. Nanoparticles, particularly those derived from natural sources, hold immense potential overcoming biological barriers to enhance therapeutic efficacy accuracy. Papain, a plant protease

10.2147/nsa.s474194 article EN cc-by-nc Nanotechnology Science and Applications 2024-09-01

Papain is a therapeutic enzyme with restricted applications due to associated allergenic reactions. nanoparticles have shown be safe for biomedical use, although method proper drug loading and release remains developed. Thus, the objective of this work was develop assess stability papain in prototype semi-solid formulation suitable dermatological or topical administrations. 7.0 ± 0.1 nm were synthesized loaded into carboxymethylcellulose- poly(vinyl alcohol)-based gels. The formulations then...

10.3390/pharmaceutics12121170 article EN cc-by Pharmaceutics 2020-12-01

Nanoparticles (NPs) with radioactive atoms incorporated within the structure of NP or bound to its surface, functionalized biomolecules are reported as an alternative low-dose-rate seed-based brachytherapy. In this study, authors report a mathematical dosimetric study on low-dose rate brachytherapy using NPs.Single-cell dosimetry was performed by calculating cellular S-values for spherical cell model Au-198, Pd-103 and Sm-153 NPs. The survival tumor volume versus time curves were calculated...

10.1088/1361-6560/abd671 article EN Physics in Medicine and Biology 2020-12-23

Less invasive and more effective cancer treatments have been the aim of research in recent decades, e.g. photothermal tumour ablation using gold nanorods. In this study we investigate cell death pathways activated, confirm possibility CTAB-coated nanoparticle use vivo. Nanorods were synthesized by seeding method; some them centrifuged washed to eliminate soluble CTAB. The MTT cytotoxicity test was performed evaluate cytotoxicity, particles' viability after their synthesis assessed. Once it...

10.1088/1054-660x/23/6/066003 article EN Laser Physics 2013-04-30

QR Codes are used as information channel on several cryptographic architectures due to their technical properties, such data capacity and retrieval reliability. This paper presents a novel string validation system using meaningless reversible degradation. The proposed scheme exploits degradation the systematic Berlekamp Reed-Solomon error correction algorithm Code. new mechanism encodes up 388 characters in two channels: dynamic version Code (channel 1) wireless network 2). A byte mode...

10.23919/ae.2019.8867027 article EN 2019-09-01
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