A5064666964- Biofuel production and bioconversion
- Complex Systems and Time Series Analysis
- Parasitic Infections and Diagnostics
- Soil Geostatistics and Mapping
- Astro and Planetary Science
- Geochemistry and Geologic Mapping
- Enzyme Catalysis and Immobilization
- Enzyme function and inhibition
- Parasite Biology and Host Interactions
- Magnetic and Electromagnetic Effects
- Trypanosoma species research and implications
- Biochemical and Molecular Research
- Nuclear Physics and Applications
- Landslides and related hazards
- Enzyme Structure and Function
- Cytomegalovirus and herpesvirus research
- RNA Interference and Gene Delivery
- Image Processing and 3D Reconstruction
- Origins and Evolution of Life
- Cassava research and cyanide
- Iron Metabolism and Disorders
- Metabolism and Genetic Disorders
- Malaria Research and Control
- Metabolomics and Mass Spectrometry Studies
- Tree Root and Stability Studies
Instituto Politécnico Nacional
2019-2024
Universidad Nacional Autónoma de México
2010-2019
Universidad Autónoma del Estado de Morelos
2019
Autonomous University of Queretaro
2009
Background Alcohol dehydrogenase (ADH) activity is widely distributed in the three domains of life. Currently, there are non-homologous NAD(P)+-dependent ADH families reported: Type I comprises Zn-dependent ADHs; type II short-chain ADHs described first Drosophila; and, III iron-containing (FeADHs). These arose independently throughout evolution and possess different structures mechanisms reaction. While types have been extensively studied, analyses about diversity (type III) FeADHs not...
Trypanosoma cruzi (T. cruzi) is a parasite that affects humans and other mammals. T. depends on glycolysis as source of adenosine triphosphate (ATP) supply, triosephosphate isomerase (TIM) plays key role in this metabolic pathway. This enzyme an attractive target for the design new trypanocidal drugs. In study, ligand-based virtual screening (LBVS) from ZINC15 database using benzimidazole scaffold was accomplished. Later, molecular docking interface TIM (TcTIM) performed compounds were...
This study presents multiwall and bamboo-like carbon nanotubes found in samples from the Allende carbonaceous chondrite using high-resolution transmission electron microscopy (HRTEM). A highly disordered lattice observed this material suggests presence of chiral domains it. Our results also show amorphous poorly-graphitized carbon, nanodiamonds, onion-like fullerenes. The have important implications for hypotheses that explain how a probable source asymmetry chondrites might contributed to...
Abstract. The solid-pore distribution pattern plays an important role in soil functioning being related with the main physical, chemical and biological multiscale multitemporal processes of this complex system. In present research, we studied aggregation process as self-organizing operating near a critical point. structural is extracted from digital images three soils (Chernozem, Solonetz "Chocolate" Clay) compared terms roughness gray-intensity quantified by several measurement techniques....
Parasitic diseases, predominantly prevalent in developing countries, are increasingly spreading to high-income nations due shifting migration patterns. The World Health Organization (WHO) estimates approximately 300 million annual cases of giardiasis. emergence drug resistance and associated side effects necessitates urgent research address this growing health concern. In study, we evaluated over eleven thousand pharmacological compounds sourced from the FDA database assess their impact on...
Iron‐containing alcohol dehydrogenases (Fe‐ADH) were initially found only in microorganisms. These enzymes catalyze different reactions, all of them assorted as dehydrogenases‐reductases. Later, a Fe‐ADH was discovered humans and animals. This has been characterized rats displaying activity hydroxyacid‐oxoacid transhydrogenase (HOT), however, its metabolic role is not completely understood. The aim our study obtain insights to understand how an ancient iron‐containing dehydrogenase/reductase...
In vertebrates, ethanol metabolism is performed through the concerted action of two enzymes: a Zn‐dependent alcohol dehydrogenase (Zn‐ADH) that oxidizes to acetaldehyde, and an aldehyde (ALDH) acetaldehyde acetate. The presence these Zn‐ADHs several ALDHs in animals has been assumed be consequence chronic exposure from diet. main natural source fermentation fruit sugars by yeast. origin angiosperms with fleshy fruits dates Lower Cretaceous (130‐140 million years ago). Because association...
Abstract. The solid-pore distribution pattern plays an important role in soil functioning being related with the main physical, chemical and biological multiscale multitemporal processes. In present research, this is extracted from digital images of three soils (Chernozem, Solonetz "Chocolate'' Clay) compared terms roughness gray-intensity (the measurand) quantified by several measurement techniques. Special attention was paid to uncertainty each them function which best fits experimental...
Alcohol dehydrogenase (ADH) activity is widely distributed in the three domains of life. Currently, there are non‐homologous NAD(P) + ‐dependent ADH families reported: Type I comprises Zn‐dependent ADHs; type II short‐chain ADHs described first Drosophila; and, III iron‐containing (FeADHs). These arose independently throughout evolution and possess different structures mechanisms reaction. While types have been extensively studied, (iron‐activated) scarcely analyzed. Therefore this work, a...
SAMPLES. We used a meteorite specimen of 297.8 g in weight, register number IG-A7, from the Colección Nacional de Meteoritas Instituto Geología, Universidad Autónoma México (UNAM), Mexico City (figure). For transmission electron microscopy (TEM), ~ 4 cm long fragment large were freshly fractured and cut by using diamond knife clean room. Later, smaller fragments (~ 50 mg total) extracted interior, avoiding contamination fusion crust or surface areas. The resulting crude sample powdered an...