A5040565894- Chemical Synthesis and Analysis
- Peptidase Inhibition and Analysis
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Monoclonal and Polyclonal Antibodies Research
- Spinal Dysraphism and Malformations
- Toxin Mechanisms and Immunotoxins
- RNA and protein synthesis mechanisms
- Cardiac Ischemia and Reperfusion
- Congenital Diaphragmatic Hernia Studies
- Plant Stress Responses and Tolerance
- HIV/AIDS Research and Interventions
- Receptor Mechanisms and Signaling
- Cardiac electrophysiology and arrhythmias
- HIV, Drug Use, Sexual Risk
- Transgenic Plants and Applications
- Sex work and related issues
- Coffee research and impacts
- Congenital Anomalies and Fetal Surgery
- Photosynthetic Processes and Mechanisms
- Treatment of Major Depression
Inserm
2019-2024
Laboratory Signaling and Cardiovascular Pathophysiology
2022-2024
Université Paris-Saclay
2024
Université Paris Cité
2022
Hôpital Saint-Louis
2021
Assistance Publique – Hôpitaux de Paris
2021
Sanofi (France)
2019
Université Laval
2016
Wageningen University & Research
2015
The overall quality of recombinant IgG antibodies in plants is dramatically compromised by host endogenous proteases. Different approaches have been developed to reduce the impact proteolysis on IgGs, notably involving site-directed mutagenesis eliminate protease-susceptible sites or situ mitigation protease activities minimize antibody processing cell secretory pathway. We here characterized degradation profile H10, a human tumour-targeting monoclonal IgG, leaves Nicotiana benthamiana also...
Objectif : La prophylaxie préexposition « PrEP » est un outil de prévention contre le VIH pour les populations à haut risque disponible depuis 2016 en France. De primoprescription CeGIDD ou hospitalière, renouvellement la peut être assuré médecine générale. L’analyse des freins cette prescription et son suivi générale indispensable afin d’atteindre objectifs nécessaires observer l’infléchissement nouvelles contaminations. Méthodes Il s’agit d’une étude descriptive menée auprès d’un...
Cardiovascular diseases represent an economic burden for health systems accounting substantial morbidity and mortality worldwide. Despite timely costly efforts in drug development, the cardiovascular safety efficacy of drugs are not always fully achieved. These lead to drugs' withdrawal with adverse cardiac effects from market or late stages development. There is a growing need cost-effective screening assay rapidly detect potential acute cardiotoxicity. The Langendorff isolated heart...