A5016182275- Advanced MRI Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Imaging and Diagnostics
- MRI in cancer diagnosis
- Cardiovascular Health and Disease Prevention
- Lanthanide and Transition Metal Complexes
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Advanced Neuroimaging Techniques and Applications
- Electron Spin Resonance Studies
- Medical Image Segmentation Techniques
- Cardiovascular Function and Risk Factors
- Advanced Vision and Imaging
- Advanced Image Processing Techniques
- Atomic and Subatomic Physics Research
- Medical Imaging Techniques and Applications
- Neurological disorders and treatments
- Advanced X-ray and CT Imaging
- Brain Tumor Detection and Classification
- Functional Brain Connectivity Studies
- Image and Signal Denoising Methods
- Retinal Imaging and Analysis
- Parkinson's Disease Mechanisms and Treatments
- Photoacoustic and Ultrasonic Imaging
- Image Processing Techniques and Applications
Shanghai Center for Brain Science and Brain-Inspired Technology
2021-2025
Shanghai Institute for Science of Science
2021-2025
Fudan University
2021-2025
Tsinghua University
2014-2024
Aviation General Hospital
2024
Beijing Institute of Technology
2024
University of Washington
2018-2024
Beihang University
2024
University of Utah
2024
Imaging Center
2020-2022
Carotid bifurcation geometry has been believed to be a risk factor for the initiation of atherosclerosis because its influence on hemodynamics. However, relationships between carotid and plaque vulnerability are not fully understood. This study aimed determine association using magnetic resonance vessel wall imaging. Approach Results: A total 501 arteries with nonstenotic were included from cross-sectional, multicenter CARE II (Chinese Atherosclerosis Risk Evaluation). Four standardized...
Purpose Optimization and validation of a sequence for measuring the labeling efficiency pseudocontinuous arterial spin (pCASL) perfusion MRI. Methods The proposed consists module single slice Look‐Locker echo planar imaging readout. A model‐based algorithm was used to calculate from signal acquired main brain‐feeding arteries. Stability measurement evaluated with regard use cardiac triggering, flow compensation vein suppression. Accuracy assessed by comparing measured mean brain pCASL...
The aim of this study was to develop, test and validate a 3D free-breathing technique for simultaneous measurement native myocardial T1 T2 .The proposed acquires five fat-suppressed electrocardiogram-triggered respiratory navigator-gated spoiled gradient echo volumes in an interleaved manner. Four are prepared using combination nonselective saturation preparation. One volume is acquired with fully recovered longitudinal magnetization accuracy during parametric fitting. Performance the...
Purpose To develop a reproducible and fast method to reconstruct MR fingerprinting arterial spin labeling (MRF‐ASL) perfusion maps using deep learning. Method A fully connected neural network, denoted as DeepMARS, was trained simulation data added Gaussian noise. Two MRF‐ASL models were used generate the data, specifically single‐compartment model with 4 unknowns parameters two‐compartment 7 unknown parameters. The DeepMARS evaluated from healthy subjects (N = 7) patients Moymoya disease 3)....
Cardiac magnetic resonance imaging (CMR) has emerged as a valuable diagnostic tool for cardiac diseases. However, limitation of CMR is its slow speed, which causes patient discomfort and introduces artifacts in the images. There been growing interest deep learning-based algorithms that can reconstruct high-quality images from highly under-sampled k-space data. development learning methods requires large training datasets, have not publicly available CMR. To address this gap, we released...
This study demonstrates a three-dimensional (3D) free-breathing native myocardial T1 mapping sequence at 3 T. The proposed acquires three differently T1-weighted volumes. first two volumes receive saturation pre-pulse with different recovery time. third volume is acquired without magnetization preparation and after significant Respiratory navigator gating volume-interleaved acquisition are adopted to mitigate misregistration. was validated through simulation, phantom experiments in vivo 12...
Purpose Applications of intravoxel incoherent motion (IVIM) imaging in the brain are scarce, whereas it has been successfully applied other organs with promising results. To better understand cerebral IVIM signal, diffusion properties arterial blood flow within different parts vascular tree (i.e., generations branching pattern) were isolated and measured by employing an spin labeling (ASL) preparation module before readout. Methods ASL was achieved T 1 ‐adjusted time‐encoded...
Vascular dysfunctions, including arterial stiffness and endothelial dysfunction, are prevalent in hypertensive subjects. We aimed to study their relations subclinical intracranial vascular health this study. A total of 200 older males without overt cardiovascular or cerebrovascular diseases were recruited. Arterial elasticity was measured as carotid-femoral pulse wave velocity (cfPWV) function digital reactive hyperemia index (RHI). Cerebrovascular evaluated using MRI four aspects:...
White matter hyperintensity (WMH) is prevalent in elderly populations. Ischemia characterized by a decline cerebral blood flow (CBF) and may play key role the pathogenesis of WMH. However, association between CBF reduction WMH progression remains controversial. This study aimed to investigate at 2-year follow-up community-based, asymptomatic adults longitudinal cohort across lifespan.Asymptomatic who participated community-based were recruited underwent brain structural perfusion magnetic...
Background Hypertension‐induced impairment of the cerebral artery network contributes to cognitive impairment. Characterizing structure and function arteries may facilitate understanding hypertension‐related pathological mechanisms lead development new indicators for Purpose To investigate associations between morphological features intracranial distal circle Willis on time‐of‐flight MRA (TOF‐MRA) performance in a hypertensive cohort. Study Type Prospective observational study. Population...
Purpose Basilar artery (BA) atherosclerosis is an important cause of perforator stroke in the brainstem due to plaque involvement ostia BA dorsal or lateral walls. Therefore, acquire information on distribution better understand and prevent stroke. This study aimed comprehensively evaluate with 3D magnetic resonance imaging (MRI) vessel wall imaging. Materials Methods Consecutive patients cerebrovascular symptoms stenosis irregular luminal surface were recruited underwent proton...
Purpose To propose a reconstruction framework to generate accurate T 1 maps for fast MR mapping sequence. Methods A deep learning–enhanced method with spatial‐temporal and physical constraint (DAINTY) was proposed. This explicitly imposed low‐rank sparsity constraints on the multiframe ‐weighted images exploit correlation. neural network used efficiently perform as well denoise reduce undersampling artifacts. Additionally, build bridge between learning prior, so benefits of constrained can...
Chemical exchange saturation transfer magnetic resonance imaging (CEST MRI) is a promising molecular tool that allows sensitive detection of endogenous metabolic changes. However, because the CEST spectrum does not display clear peak like MR spectroscopy, its signal interpretation challenging, especially under 3-T field strength or with large B1 . Herein, as an alternative to conventional Z-spectral fitting approaches, permuted random forest (PRF) method developed determine featured...
With the lack of energy and amazing development automobile industry, new electric vehicles are bound to become one important means transportation in future Permanent magnet synchronous motor drive is most critical power component vehicles, its performance determines driving quality whole vehicle This paper designs circulating cooling system according requirements temperature threshold The thermal simulation analysis designed heat dissipation structure carried out Compare test value with...
Developing novel risk markers for vascular contributions to cognitive impairment and dementia is important. This study aimed extract total length, branch number average tortuosity of intracranial distal arteries (A2, M2, P2 more distal) from non-contrast enhanced magnetic resonance angiography (NCE-MRA) images, explore their associations with global cognition. In 29 subjects (aged 40-90 years) carotid atherosclerotic disease, the 3 features on two NCE-MRA techniques (i.e. time flight, TOF...
Cardiac MRI, crucial for evaluating heart structure and function, faces limitations like slow imaging motion artifacts. Undersampling reconstruction, especially data-driven algorithms, has emerged as a promising solution to accelerate scans enhance performance using highly under-sampled data. Nevertheless, the scarcity of publicly available cardiac k-space datasets evaluation platform hinder development reconstruction algorithms. To address this issue, we organized MRI Reconstruction...
Background Quantitative T1, T2, and T2* measurements of carotid atherosclerotic plaque are important in evaluating vulnerability monitoring its progression. Purpose To develop a sequence to simultaneously quantify plaque. Materials Methods The simultaneous mapping (SIMPLE*) is composed three modules with different T2 preparation pulses, inversion-recovery acquisition schemas. Single-echo data were used for T1 quantification, while the multiecho (ME) quantification. quantitative accuracy...