Gamze Erzın
- Tryptophan and brain disorders
- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Health, Environment, Cognitive Aging
- Diet and metabolism studies
- COVID-19 and Mental Health
- Mental Health Treatment and Access
- Adipose Tissue and Metabolism
- Impact of Technology on Adolescents
- Mental Health and Psychiatry
- Cannabis and Cannabinoid Research
- Stress Responses and Cortisol
- Child Development and Digital Technology
- Adenosine and Purinergic Signaling
- Healthcare professionals’ stress and burnout
- Electroconvulsive Therapy Studies
- Fetal and Pediatric Neurological Disorders
- Digital Mental Health Interventions
- Employment and Welfare Studies
- Nutritional Studies and Diet
- Dental Research and COVID-19
- Long-Term Effects of COVID-19
- Electrolyte and hormonal disorders
- Psychosomatic Disorders and Their Treatments
- Global Health Workforce Issues
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2016-2024
Sağlık Bilimleri Üniversitesi
2021-2024
Maastricht University
2021-2024
Maastricht University Medical Centre
2023-2024
Ministry of Health
2016-2022
Başkent University
2021
Memorial Ankara Hospital
2019
Ankara Numune Eğitim ve Araştırma Hastanesi
2015-2018
A specific clinically relevant staging model for schizophrenia has not yet been developed. The aim of the current study was to evaluate factor structure PANSS and develop such a method.Twenty-nine centers from 25 countries contributed 2358 patients aged 37.21 ± 11.87 years with schizophrenia. Analysis covariance, Exploratory Factor Analysis, Discriminant Function inspection resultant plots were performed.Exploratory returned 5 factors explaining 59% variance (positive, negative,...
Abstract Background The prevalence of medical illnesses is high among patients with psychiatric disorders. current study aimed to investigate multi-comorbidity in disorders comparison the general population. Secondary aims were factors associated metabolic syndrome and treatment appropriateness mental Methods sample included 54,826 subjects (64.73% females; 34.15% males; 1.11% nonbinary gender) from 40 countries (COMET-G study). analysis was based on registration previous history that could...
Objectives This survey assessed psychiatry residents'/early-career psychiatrists' attitudes towards the utility of therapeutic drug monitoring (TDM) antipsychotics.
Previously, we established an estimated exposome score for schizophrenia (ES-SCZ) as a cumulative measure of environmental liability to use in gene-environment interaction studies and risk stratification population cohorts. Hereby, examined the discriminative function ES-SCZ identifying individuals diagnosed with spectrum disorder general by measuring area under receiver operating characteristic curve (AUC). Furthermore, compared this method sum (Esum-SCZ) aggregate weighted meta-analytical...
Abstract Background A cumulative environmental exposure score for schizophrenia (exposome [ES-SCZ]) may provide potential utility risk stratification and outcome prediction. Here, we investigated whether ES-SCZ was associated with functioning in patients spectrum disorder, unaffected siblings, healthy controls. Methods This cross-sectional sample consisted of 1,261 patients, 1,282 1,525 The Global Assessment Functioning (GAF) scale used to assess functioning. calculated based on our...
Social cognition impairments, such as facial emotion recognition (FER), have been acknowledged since the earliest description of schizophrenia. Here, we tested FER an intermediate phenotype for psychosis using two approaches that are indicators genetic risk schizophrenia: proxy-genetic approach (family design) and polygenic score schizophrenia (PRS-SCZ).The sample comprised 2039 individuals with schizophrenia, 2141 siblings, 2049 healthy controls (HC). The Degraded Facial Affect Recognition...
Abstract Background Problematic Internet gaming is an increasingly recognized global mental health problem. This multicultural cross-sectional study examined the association between disorder (IGD) symptoms and anxiety depressive substance use within a sample of young users. In total, 3529 college/university students (1260 (35.7%) males; mean age 21 ± 3 years) were surveyed online. We assessed online patterns using Gaming Disorder Self-report for College/University Students (ICMH-IGD),...
Abstract Background Evidence suggests that environmental factors not only increase psychosis liability but also influence the prognosis and outcomes of psychotic disorders. We investigated temporal cross-sectional associations a weighted score cumulative for schizophrenia – exposome (ES-SCZ) with functioning in first-episode (FEP). Methods Data were derived from baseline 1-month assessments Athens FEP Research Study enrolled 225 individuals FEP. The Global Assessment Functioning (GAF)...
The present study evaluated the psychometric properties of a self-report scale for assessing Internet Gaming Disorder (IGD) symptoms according to DSM?5 and ICD?11 among 3270 college/university students (2095 [64.1%] females; age mean 21.6 [3.1] years) from different countries worldwide. Croatian, English, Polish, Portuguese, Serbian, Turkish, Vietnamese versions were tested. showed that IGD could be measured as single underlying factor students. A nine item symptom following DSM?5, short...
This study aims to investigate the dynamic thiol/disulphincide homeostasis in patients with schizophrenia who have positive psychotic indications.Forty-four (26 males, 18 females; mean age = 34.40 ± 8.98 years) accepted at Department of Psychiatry Ankara Numune Training and Research Hospital 33 healthy controls (15 30.30 8.48 were included study. Serum native thiol total measured a novel colorimetric, automated method. The disulfide levels disulfide/native ratios also calculated from these...
Schizophrenia is frequently accompanied with social cognitive disturbances. Cannabis represents one established environmental factor associated the onset and progression of schizophrenia. The present cross-sectional study aimed to investigate association facial emotion recognition (FER) performance cannabis use in 2039 patients schizophrenia, 2141 siblings, 2049 healthy controls (HC). FER was measured using Degraded Facial Affect Recognition Task (DFAR). Better as indicated by higher...
People with schizophrenia spectrum disorders (SSD) frequently present cognitive impairments. Here, we investigated whether the exposome score for (ES-SCZ) - a cumulative environmental exposure was associated impairments of neurocognition, social cognition, and perception in patients SSD, their unaffected siblings, healthy controls.This cross-sectional sample consisted 1200 patients, 1371 1564 controls. Neurocognition, were assesed using short version Wechsler Adult Intelligence Scale-Third...
The aim of the current study was to explore changing interrelationships among clinical variables through stages schizophrenia in order assemble a comprehensive and meaningful disease model.Twenty-nine centers from 25 countries participated included 2358 patients aged 37.21 ± 11.87 years with schizophrenia. Multiple linear regression analysis visual inspection plots were performed.The results suggest that progression stages, there are correlations Positive Negative Syndrome Scale factors at...
Gokhan Guney, Busra Ozgode Yigin, Necdet Guven, Yasemin Hosgoren Alici, Burcin Colak, Gamze Erzin, Gorkem Saygili. Clin Psychopharmacol Neurosci 2021;19:206-19. https://doi.org/10.9758/cpn.2021.19.2.206
A low-grade inflammation is presumed to be related the etiopathogenesis of major depressive disorder (MDD) and bipolar disorder. Tumor necrosis factor (TNF) superfamily members have roles in pathogenesis neuropsychiatric disorders because relationship with neurogenesis. The aim this study was investigate serum TNF-related weak inducer apoptosis (TWEAK) apoptosis-inducing ligand (TRAIL) levels patients depression (BD), MDD a healthy control (HC) group determine any differences between BD...