Ida S. Haussleiter
A5091254474- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Psychiatric care and mental health services
- Healthcare Decision-Making and Restraints
- Mental Health Treatment and Access
- Tryptophan and brain disorders
- Child and Adolescent Psychosocial and Emotional Development
- Genetic Associations and Epidemiology
- Homelessness and Social Issues
- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Obsessive-Compulsive Spectrum Disorders
- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Autoimmune Neurological Disorders and Treatments
- Psychosomatic Disorders and Their Treatments
- Mental Health and Psychiatry
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Child Abuse and Trauma
- Advancements in Transdermal Drug Delivery
- Musculoskeletal pain and rehabilitation
- Digital Mental Health Interventions
- Geriatric Care and Nursing Homes
- Cannabis and Cannabinoid Research
- Health Literacy and Information Accessibility
LWL-Universitätsklinikum Bochum
2016-2025
Ruhr University Bochum
2013-2025
BG University Hospital Bergmannsheil Bochum
2008-2009
University of North Texas
2009
University of North Texas Health Science Center
2009
In-Q-Tel
2008
In current diagnostic systems, schizophrenia and bipolar disorder are still conceptualized as distinct categorical entities. Recently, both clinical genomic evidence have challenged this Kraepelinian dichotomy. There only few longitudinal studies addressing potential overlaps between these conditions. Here, we present design first results of the PsyCourse study ( N = 891 individuals at baseline), an ongoing transdiagnostic affective‐to‐psychotic continuum that combines deep phenotyping...
Identifying psychosis subgroups could improve clinical and research precision. Research has focused on symptom subgroups, but there is a need to consider broader spectrum, disentangle illness trajectories, investigate genetic associations.To detect using data-driven methods examine their courses over 1.5 years polygenic scores for schizophrenia, bipolar disorder, major depression educational achievement.This ongoing multisite, naturalistic, longitudinal (6-month intervals) cohort study began...
Abstract Autoimmune encephalitis (AE) can rarely manifest as a predominantly psychiatric syndrome without overt neurological symptoms. This study’s aim was to characterize patients with AE; therefore, anonymized data on suspected AE or isolated syndromes were retrospectively collected. Patients readily detectable symptoms suggestive of (e.g., epileptic seizures) excluded. classified “probable (pAE),” if well-characterized neuronal IgG autoantibodies detected “possible pAE” detection...
Abstract Lithium is regarded as the first-line treatment for bipolar disorder (BD), a severe and disabling mental health that affects about 1% of population worldwide. Nevertheless, lithium not consistently effective, with only 30% patients showing favorable response to treatment. To provide personalized options patients, it essential identify prediction biomarkers such polygenic scores. In this study, we developed score (Li + PGS ) in BD. gain further insights into lithium’s possible...
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system. Demyelinization nerve fibres not only affects motor and sensory systems functionally, but may also cause psychopathological signs symptoms. In addition to psychiatric manifestations MS, many patients have reactive psychological problems that are often hard distinguish from `organic' causation psychopathology. any event, comorbidity in MS deserves greater clinical attention than has been previously paid,...
Dysesthesias of the lower limbs are a common complaint patients and may be indicative peripheral neuropathy. Here we investigated prevalence type neuropathy in presenting with this compared diagnostic performance different modalities. Forty-two were recruited prospectively underwent clinical examination, nerve conduction studies, quantitative sensory testing (QST), skin biopsy at dorsum foot. All had correlate for their dysesthesias least one modality. Most (>90%) signs small fiber loss or...
A specific clinically relevant staging model for schizophrenia has not yet been developed. The aim of the current study was to evaluate factor structure PANSS and develop such a method.Twenty-nine centers from 25 countries contributed 2358 patients aged 37.21 ± 11.87 years with schizophrenia. Analysis covariance, Exploratory Factor Analysis, Discriminant Function inspection resultant plots were performed.Exploratory returned 5 factors explaining 59% variance (positive, negative,...
Background: Germany provides a wide range of highly developed mental health care to its citizens. The aim this study was identify factors influencing the voluntariness admissions psychiatric hospitals. Especially impact demographic region, characteristics hospitals and psychosocial services analyzed. Method: A retrospective analysis hospital admission registers from 13 German adult in 2009 conducted. Public data on regional accommodation situation were added. Hospitals dichotomously divided...
Abstract As early detection of symptoms in the subclinical to clinical psychosis spectrum may improve health outcomes, knowing probabilistic susceptibility developing a disorder could guide mitigation measures and intervention. In this context, polygenic risk scores (PRSs) quantifying additive effects multiple common genetic variants hold potential predict complex diseases index severity gradients. PRSs for schizophrenia (SZ) bipolar (BD) were computed using Bayesian regression continuous...
Abstract Background Polygenic scores (PGSs) hold the potential to identify patients who respond favourably specific psychiatric treatments. However, their biological interpretations remain unclear. In this study, we developed pathway-specific PGSs (PS PGS ) for lithium response and assessed association with clinical in bipolar disorder (BD). Methods Using sets of genes involved pathways affected by lithium, nine PS evaluated associations International Consortium on Lithium Genetics cohort...
Despite marked costs and limited evidence regarding effectiveness, occupational therapy (OT) is widely applied in psychiatric settings financed by health insurance companies European countries. This pilot study investigated the antidepressive effects of adjuvant OT for patients with major depression a 6-week inpatient setting, stratified females males.A total 114 inpatients were assigned to either standard group (using basic handcraft) or an active control that played board games (2 h daily,...
Introduction The prevalence of mental health problems is increasing worldwide, particularly in the vulnerable group older people. limited availability therapists, long wait periods and shortage healthcare resources limit adequate care. As a result, digital applications are becoming more commonplace as an alternative to human therapists. However, these tend be used by younger people with higher education, literacy experience. In Germany, that approved authorities, so-called (DiGAs), can...
Little is known about uptake of mental healthcare services by homeless people and even less those living in precarious housing. The "WohnLos" study determined the prevalence non-secure housing (defined as homelessness or housing) among inpatients two groups public health hospitals state North Rhine-Westphalia (NRW), Germany. We conducted a questionnaire survey hospital groups, which provide in- out-patient for population ten million people. Clinical staff filled every inpatient on record...
Abstract Background In the face of extensive waiting times for outpatient psychotherapy, prescriptible digital health applications (DiGA) are a useful and effective addition to range available therapy options patients with mild moderate depression. However, older adults particular challenge in implementing DiGA since higher age is decisive predictor lower literacy. The necessity an independent use prescribed therefore associated challenges providers. practice, it crucial not leave patients,...
Dysaesthesias is a common symptom in patients with neuropathic pain after peripheral nerve injury (PNI). In contrast to neuropathies comparable symptoms there little knowledge of the underlying mechanisms PNI patients.Quantitative sensory testing according German Research Network on Neuropathic Pain protocol, and changes intraepidermal fiber density were assessed 15 dysaesthesias lower limb. According their small-fiber function assigned into 2 subgroups.The profiles characterized...
<b>Ziel:</b> In dieser Studie wurden 40 untergebrachte Patienten durchschnittlich 3 Wochen nach erfolgter Zwangsmaßnahme zu ihrem Erleben befragt. <b>Methode:</b> Der Fragebogen umfasste 31 Items demografischen und krankheitsbezogenen Daten, Modalitäten der Unterbringung, Zwangsmaßnahmen im Rahmen Unterbringung ihre Empfindung sowie Patientenzufriedenheit. Letzteres wurde bisher nicht detailliert untersucht. <b>Schlussfolgerung:</b> Als führende Emotionen in Zwangssituation Wut, Ärger...
<b>Ziel der Studie:</b> Bundesweit hat die Zahl unfreiwilliger Aufnahmen von psychisch Kranken in psychiatrischen Krankenhäusern nach PsychKG oder BtG zugenommen. Jedoch ist bislang wenig über Bedingungsfaktoren hierfür bekannt. <b>Methodik:</b> Anhand einer Stichprobe mit 200 000 Behandlungsfällen aus Nordrhein-Westfalen wurde dieses untersucht. <b>Ergebnisse:</b> Ältere Patienten Demenz wurden am häufigsten untergebracht. Das Vorhandensein geschlossenen Station spielte keine Rolle. zeigte...
Coercive measures in psychiatry are a controversial topic and raise ethical, legal clinical issues. Involuntary admission of patients is long-lasting problem indicates problematic pathway to care situations within the community, largely because personal freedom fundamentally covered by UN declaration human rights German constitution. In this study, survey on large comprehensive population psychiatric in-patients eastern part North Rhine-Westphalia, Germany, was carried out for years...
Sleep dysfunction is a core symptom in bipolar disorder (BD), especially during major mood episodes. This study investigated the possible link between subjective and objective sleep disturbances inter-episode BD, changes melatonin cortisol levels, circadian alignment. The included 21 euthymic BD patients 24 healthy controls. Participants had to wear an actigraphy device, keep weekly diary take salivary samples: five samples on last evening determine dim light onset (DLMO) one following...