A5101398199- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Traditional Chinese Medicine Studies
- Atomic and Subatomic Physics Research
- Acupuncture Treatment Research Studies
- Epilepsy research and treatment
- Radiomics and Machine Learning in Medical Imaging
- Diet and metabolism studies
- Bone health and osteoporosis research
- Advanced NMR Techniques and Applications
- Palliative Care and End-of-Life Issues
- Kawasaki Disease and Coronary Complications
- Genetics and Neurodevelopmental Disorders
- Renal and related cancers
- Patient-Provider Communication in Healthcare
- Ferroptosis and cancer prognosis
- Healthcare and Venom Research
- Nuclear Physics and Applications
- Metabolism and Genetic Disorders
- Bone and Joint Diseases
- Polyomavirus and related diseases
- Abdominal Trauma and Injuries
- Atherosclerosis and Cardiovascular Diseases
- Patient Dignity and Privacy
Shenzhen Children's Hospital
2015-2024
Shandong Provincial QianFoShan Hospital
2019-2024
Shandong First Medical University
2019-2024
West China Second University Hospital of Sichuan University
2007-2023
Sichuan University
2006-2023
University of South China
2023
Institute of Agricultural Resources and Regional Planning
2023
Hangzhou Medical College
2023
North University of China
2022
University of Pennsylvania
2014-2020
Abstract Objective : Cancer patients and their families differed in attitude toward truth telling. The objective is to investigate different attitudes of Chinese or whether how disclose diagnosis with stages cancer examine the difference between two groups. Methods A questionnaire was delivered 1023 participants. Results Three hundred eighty‐two 482 completed questionnaire. were more likely than believe that patient should be informed (early‐stage, 90.8 vs 69.9%, P <0.001; terminal stage,...
To develop and evaluate an integrated imaging protocol for bone water phosphorus quantification in vivo by solid-state 1H 31P MRI.All studies were HIPAA-compliant performed with institutional review board approval written informed consent. Proton (1H) ultra-short echo-time (UTE) (31P) zero (ZTE) sequences designed implemented on a 3 T clinical MR scanner to quantify mineral vivo. The left tibia of ten healthy subjects (including both genders, 49±15 y/o) was examined custom-built 1H/31P...
Neurotoxicity can be resulted from many diverse clinical drugs, which has been a cause of concern to human populations across the world. The detection drug-induced neurotoxicity (DINeurot) potential with biological experimental methods always required lot budget and time. In addition, few studies have addressed structural characteristics neurotoxic chemicals. this study, we focused on computational modeling for machine learning insights into Based drug data effects, developed 35 different...
Abstract To evaluate the diagnostic efficacy and clinical value of contrast-enhanced ultrasonography (CEUS) plus TI-RADS classification in benign malignant thyroid tumors compared with either method alone. The informed consent was signed all patients. A total 370 patients category 3 4 were recruited, 432 nodules. They respectively received routine CEUS. nodules reclassified according to CEUS scoring, a combined diagnosis made. pathological results taken as gold standard. sensitivity (Se),...
Purpose To design and evaluate an optimized PETRA (point‐wise encoding time reduction with radial acquisition) sequence long‐ T 2 suppression at 3 Tesla. Methods An adiabatic inversion recovery‐based scheme was used to null the signal. minimize scan time, signal sampled multiple times after each variable excitation flip angles designed yield constant short‐ amplitude. The pulses were phase‐modulated, allowing for increased angle higher signal‐to‐noise ratio (SNR). A fast, noniterative image...
Patients with acute ischemic stroke (AIS) often experience low serum free triiodothyronine (FT3), but the association of FT3 severity, subtype and prognosis has not yet been thoroughly studied, molecular events underlying these clinical observation were also unclear.We retrospectively collected 221 cases AIS 182 non-AIS detailed data from our department. concentrations measured on admission to predict functional outcome within 3 months using multivariable models adjusted for other risk...
Background: The prognosis of patients with advanced cervical cancer remains unsatisfactory. A study indicated that transmembrane protein 33 (TMEM33) was implicated in tumor recurrence, while its role has not been elucidated. Methods: TMEM33 expression squamous cell carcinoma and endocervical adenocarcinoma (CESC) primarily screened Cancer Genome Atlas (TCGA), further validated Gene Expression Omnibus (GEO) database. Kaplan-Meier plotter analysis Cox regression were constructed to evaluate...
Purpose To develop a dual‐radiofrequency (RF), dual‐echo, 3D ultrashort echo‐time (UTE) pulse sequence and bone‐selective image reconstruction for rapid high‐resolution craniofacial MRI. Methods The proposed builds on recently introduced dual‐RF UTE imaging. While yielding enhanced bone specificity by exploiting high sensitivity of short T 2 signals to variable RF widths, the parent technique exacts 2‐fold scan time penalty relative standard dual‐echo UTE. In method, sequence’s scheme was...
Ultrashort echo time (UTE) MRI is capable of detecting signals from protons with very short T2 relaxation times, and thus has potential for skull-selective imaging as a radiation-free alternative to computed tomography. However, relatively long scan times make the technique vulnerable artifacts involuntary subject motion. Here, we developed self-navigated, three-dimensional (3D) UTE pulse sequence, which builds on dual-RF, dual-echo imaging, retrospective motion correction scheme...
Purpose The impact of gradient imperfections on UTE images and image‐derived bone water quantification was investigated at 3 T field strength. Methods effects simple time delays eddy currents images, as well the error corrections, were studied with simulation phantom experiments. k‐space trajectory mapped a 2D sequence phase encoding both spatial axes by measuring signal in small increments during ramp‐up read gradient. In vivo 3D reconstructed without compensation to determine bias...
Compressed Sensing (CS) and parallel imaging are two promising techniques that accelerate the MRI acquisition process. Combining these is of great interest due to complementary information used in each. In this study, we proposed a novel reconstruction framework effectively combined compressed sensing nonlinear technique for dynamic cardiac imaging. Specifically, method decouples process into sequential steps: first step, series aliased images were reconstructed from highly undersampled...
Purpose The intersubject variations in bone phosphorus‐31 ( 31 P) T 1 and , as well the implications on vivo P MRI‐based mineral quantification, were investigated at 3T field strength. Methods A technique that isolates signal from composite spectrum was first evaluated via simulation experiments ex subsequently applied to measure of collectively with a spectroscopic saturation recovery sequence group healthy subjects aged 26 76 years. derived linewidth. density for all zero TE images...
The prevalence of epilepsy in sub-Saharan Africa is higher than other parts the world, but it short effective measure on treating intractable epilepsy. Epilepsy surgery not easy to be performed due high cost and demand operational skills. authors planned perform ketogenic diet therapy for children with Ghana regard its low simple procedure. candidate a 10-month-old girl unknown etiology. Her seizures couldn’t controlled by more 3 antiepileptic drugs. development delayed severely frequent...
Sirolimus is confirmed to be effective in the treatment of tuberous sclerosis complex (TSC) and related disorders. The study aims establish a population pharmacokinetic model oral sirolimus for children with TSC provide an evidence-based approach individualization dosing pediatric population. A total 64 were recruited this multicenter, retrospective study. Whole-blood concentrations sirolimus, demographic, clinical information collected analyzed using nonlinear mixed-effects modeling method....