A5025951853- Reconstructive Facial Surgery Techniques
- Ear Surgery and Otitis Media
- Reconstructive Surgery and Microvascular Techniques
- Ear and Head Tumors
- Nasal Surgery and Airway Studies
- Congenital Ear and Nasal Anomalies
- Ocular Disorders and Treatments
- Facial Nerve Paralysis Treatment and Research
- Oral and Maxillofacial Pathology
- Tissue Engineering and Regenerative Medicine
- Pharmacological Effects of Natural Compounds
- Lipid metabolism and biosynthesis
- Muscle and Compartmental Disorders
- Ginseng Biological Effects and Applications
- Facial Trauma and Fracture Management
- Healthcare and Venom Research
- Teratomas and Epidermoid Cysts
- Drug Transport and Resistance Mechanisms
- Traditional Chinese Medicine Analysis
- Adipose Tissue and Metabolism
- Antibiotics Pharmacokinetics and Efficacy
- Wound Healing and Treatments
- Mesenchymal stem cell research
- Craniofacial Disorders and Treatments
- Hemostasis and retained surgical items
Shanghai Jiao Tong University
2016-2025
Shanghai Ninth People's Hospital
2005-2025
Bridge University
2020
Weatherford College
2019
ING Direct
2015
Anyang Hospital of Traditional Chinese Medicine
2015
SAIC-GM (China)
2014
Wuhan University
2009
State Key Laboratory of Virology
2009
Renmin Hospital of Wuhan University
2009
Background: Favorable results in auricular reconstruction are difficult to achieve. The authors report 350 patients with different types of microtia who underwent total ear reconstruction. youngest was aged 5.5 years and the oldest 50 years. Methods: performed using autologous costal cartilage combination Brent Nagata methods, some modifications. At first stage, an individualized framework fabrication based on degrees strength thickness rib cartilages performed. One piece added vertically...
Microtia is a congenital malformation characterized by underdevelopment of the external ear. While chondrocyte dysfunction has been implicated in microtia, specific cellular abnormalities remain poorly understood. This study aimed to investigate mitochondrial microtia chondrocytes using single-cell RNA sequencing. Cartilage samples were obtained from patients with unilateral, non-syndromic and healthy controls. Single-cell sequencing was performed 10 × Genomics platform. Bioinformatic...
This study was designed to explore the pharmacokinetic interaction of Panax Ginseng with fexofenadine in rats. Sprague-Dawley (SD) male rats were divided randomly into four groups: control oral and treatment dose groups ( n = 6, respectively); intravenous 5, respectively). A single (10 mg/kg for group 100 rats) administered after 14 consecutive days gastric gavage feeding panax ginseng suspension (150 mg/kg/day) while same volume vehicle (1.6% ethanol) as placebo groups. Blood samples...
Prior reports of ear reconstruction have cited favorable results. Although greater attention has been devoted to fabricating a more refined cartilaginous framework, many patients still complain that the contours are unnatural. The authors' aim was offer new technique resolves some lingering issues.To fabricate antihelix complex optimally, authors modified an existing method. Rather than chiseling sharp, Y-shaped graft cartilage for structural prominence, superior crus is broadened, and...
Congenital anomalies of the external ear can have a significant impact on child's development and quality life. While genetic factors play crucial role in etiology these anomalies, environmental such as drug exposure during pregnancy may also contribute to their occurrence. This study aims investigate association between congenital using data from an adverse reaction report database. Using OpenVigil 2.1, we queried FAERS database retrieve event reports first quarter 2004 2024. To identify...
Patients' satisfaction is an increasingly important indicator for successful ear reconstruction surgeries. However, there no scientifically sound patient-based outcome instrument in this field. This study aims at developing a patient-reported measure microtia investigating patients' and perception of reconstructed clinical researches.The development questionnaire included 3 stages. Traditional psychometric tests were used analysis. At first stage, preliminary version the was developed using...
Abstract Despite various surgical techniques for ear elevation in autogenous cartilage microtia reconstruction, it is still challenging plastic surgeons to obtain a satisfactory depth of the cephaloauricular sulcus and stable projection reconstructed ear. Here, authors demonstrate individualized options approaches relevant details complication management. Between January 2014 June 2020, series 895 patients who underwent second stage reconstruction were reviewed. Complications occurred 103...
SUMMARY The aim of the present study was to examine effect bacterial lipopolysaccharide (LPS) on disposition an organic anion transporting polypeptide and P‐glycoprotein substrate in rat isolated perfused liver. Male Sprague‐Dawley rats were divided into four groups. Three groups received 1, 2.5 or 5 mg/kg, i.p., Escherichia coli LPS sterile saline. fourth group equivalent volume saline i.p. Twenty‐four hours after treatment, anaesthetized liver with fexofenadine at initial concentration...
Although complications of ear reconstruction are rare, common salvage procedures involve invasive surgery, and final outcomes can be uncertain. In this study, the authors have successfully applied noninvasive hyperbaric oxygen therapy (HBOT) as an adjunct treatment for reconstruction.During a 2-year period, 42 patients with were included in study. All received HBOT twice day 2 to 3 courses, each course lasted 10 days.Patients suffered from 4 different complications: hematoma (15), flap...