A5036823216- Advancements in Transdermal Drug Delivery
- Curcumin's Biomedical Applications
- Essential Oils and Antimicrobial Activity
- Monoclonal and Polyclonal Antibodies Research
- Nanoparticle-Based Drug Delivery
- Enzyme Catalysis and Immobilization
- Wildlife Ecology and Conservation
- Synthesis and biological activity
- Brain Metastases and Treatment
- COVID-19 Clinical Research Studies
- Advanced Drug Delivery Systems
- Lipid Membrane Structure and Behavior
- Radiopharmaceutical Chemistry and Applications
- Chemical Synthesis and Reactions
- Heavy metals in environment
- Nanoparticles: synthesis and applications
- Inorganic and Organometallic Chemistry
- Air Quality and Health Impacts
- Heavy Metal Exposure and Toxicity
- Immunotherapy and Immune Responses
- Computational Drug Discovery Methods
- Glioma Diagnosis and Treatment
- Enzyme Production and Characterization
- Microbial infections and disease research
- Animal Ecology and Behavior Studies
Centre International de Recherche sur le Cancer
2023-2025
Semnan University of Medical Sciences
2025
University of Zanjan
2020-2024
Shahid Beheshti University of Medical Sciences
2020-2024
Geological Survey of Iran
2023-2024
Kerman University of Medical Sciences
2017-2023
Zanjan University of Medical Sciences
2021-2023
Shiraz University of Medical Sciences
2003-2022
University of Sistan and Baluchestan
2018-2022
Shahid Beheshti University
2018-2022
At present, novel Coronavirus (2019-nCoV, the causative agent of COVID-19) has caused worldwide social and economic disruption. The disturbing statistics this infection promoted us to develop an effective vaccine candidate against COVID-19. In study, bioinformatics approaches were employed design introduce a multi-epitope 2019-nCoV that can potentially trigger both CD4+ CD8+ T-cell immune responses investigated its biological activities by computational tools. Three known antigenic proteins...
Brain tissue manganese (Mn) accumulation is a cirrhosis-associated complication. Cellular mitochondria are among the potential targets for Mn-induced cytotoxicity. Taurine one of most abundant amino acids with high concentrations in human brain tissue. Several pharmacological properties including regulation mitochondrial function attributed to taurine. The current investigation was designed evaluate effect taurine on impairment isolated mice mitochondria. were exposed increasing Mn (0.1-10...
Because of the nutritional ecology dung- and carrion-feeding, bacteria are integral part Lucilia sericata life cycle. Nevertheless, disinfected larvae blowfly applied to treat human chronic wounds in a biosurgery named maggot debridement therapy (MDT). To realize effects location/diet on gut bacteria, infer role plus MDT process, disclose circulating horizontally vertically between generations, bacterial communities associated with L. specimens from various sources were investigated using...
The 2018 World Cancer Research Fund/American Institute for (WCRF/AICR) Third Expert Report, including studies up to 2015, determined 'limited-no conclusion' evidence on dietary patterns and colorectal cancer (CRC) risk due insufficient data varying pattern definitions. This updated review synthesized literature CRC risk/mortality. PubMed Embase were searched through 31 March 2023 randomized controlled trials (RCTs) prospective cohort adulthood patterns. Patterns categorized by derivation...
This study explores whether resveratrol effectively protects the reproductive system against isoflurane-induced toxicity in testicular tissue. In this experiment, we randomly divided 60 adult male C57BL/6 mice into six groups (n = 10). Five consecutive days per week, were exposed to 1.5% isoflurane for 1 h/day and given 50 100 mg/kg resveratrol. After 35 (the completion of mouse spermatogenesis period), left testis was removed histomorphometric evaluations, while right used determine...
Cyclooxygenase-2 (COX-2), the key enzyme in arachidonic acid conversion to prostaglandins, is one of enzymes associated with different pathophysiological conditions, such as inflammation, cancers, Alzheimer's, and Parkinson's disease. Therefore, COX-2 inhibitors have emerged potential therapeutic agents these diseases.
The widespread use of pesticides in agriculture represents a threat to the human populations exposed them. In this cross-sectional study, hematological and biochemical parameters, plasma cholinesterase (PChE) activity, oxidative stress, genotoxicity, NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism were measured 100 greenhouse workers occupationally pesticide mixture 104 normal healthy controls. There was decrease erythrocytes (5.45%, p = 0.026) hemoglobin (3.26%, 0.025), an...
Abstract The aim of the present study was to design a delivery system curcumin (CU) loaded solid lipid nanoparticles (CU‐CSLNs) for evaluating antimicrobial properties in hamburger patty. Solid nanoparticle (SLN) prepared through homogenizing technique. A response surface methodology applied optimize CU‐CSLNs minimize particle size (PS), polydispersity index (PDI), as well maximize zeta potential avoid aggregation particles. optimized sample revealed spherical morphology under scanning...
To determine the clinical characteristics and outcomes of COVID-19 in a large cohort new cancer patients referred to an oncology clinic north Iran.During 20-month pandemic, were followed-up. Demographic, pathologic, variables collected for each patient. was confirmed based on positive polymerase chain reaction test. Analyses performed using STATA version 14.0 at significance level 0.05.In this study, 1294 followed 24 months (mean age: 58.7 years [range 10-95]). During study period, diagnosed...
Bladder cancer (BC) is the 10th most common in world. While there are FDA-approved urinary assays to detect BC, none have demonstrated sufficient sensitivity and specificity be integrated into clinical practice. Telomerase Reverse Transcriptase (TERT) gene mutations been identified as BC that could potentially used non-invasive biomarkers BC. This study aims evaluate validity of these tests Kerman province Iran, where men. Urine samples 31 patients with primary (n = 11) or recurrent 20)...