Zi Yan

ORCID: 0000-0001-8188-5549
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About
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Research Areas
  • Physical Activity and Health
  • Obesity, Physical Activity, Diet
  • Behavioral Health and Interventions
  • Autophagy in Disease and Therapy
  • Children's Physical and Motor Development
  • Eating Disorders and Behaviors
  • Mitochondrial Function and Pathology
  • Food composition and properties
  • Plant Disease Resistance and Genetics
  • Youth Development and Social Support
  • Rice Cultivation and Yield Improvement
  • Wheat and Barley Genetics and Pathology
  • Advanced Neuroimaging Techniques and Applications
  • Motivation and Self-Concept in Sports
  • Cardiac Arrest and Resuscitation
  • School Health and Nursing Education
  • COVID-19 and Mental Health
  • Neurological Disease Mechanisms and Treatments
  • Physical Education and Pedagogy
  • Receptor Mechanisms and Signaling
  • Endoplasmic Reticulum Stress and Disease
  • Crop Yield and Soil Fertility
  • Functional Brain Connectivity Studies
  • Down syndrome and intellectual disability research
  • Health and Wellbeing Research

Merrimack College
2016-2025

Shandong Academy of Agricultural Sciences
2019-2025

Ministry of Agriculture and Rural Affairs
2021-2025

Mudanjiang Medical University
2025

Southern Medical University
2022-2024

Third Affiliated Hospital of Southern Medical University
2022-2024

Shanxi Medical University
2012-2024

Wuyi University
2024

The First Affiliated Hospital, Sun Yat-sen University
2011-2024

Sun Yat-sen University
2011-2024

People's feelings toward physical activity are often influenced by memories of their childhood experiences in education and sport. Unfortunately, many adults remember negative experiences, which may affect desire to maintain a physically active lifestyle. A survey that asked 293 students about recollections from or youth sport revealed participants who had been picked chosen last for team significant reduction later life. Long recognized as an “inappropriate” instructional practice NASPE,...

10.1080/07303084.2013.767736 article EN Journal of Physical Education Recreation & Dance 2013-03-01

Abstract To effectively treat osteoarthritis (OA), the existing inflammation must be reduced before cartilage damage can repaired; this cannot achieved with a single type of extracellular vesicles (EVs). Here, hydrogel complex logic‐gates function is proposed that spatiotemporally controlled release two types EVs: interleukin 10 (IL‐10) + EVs to promote M2 polarization macrophage, and SRY‐box transcription factor 9 (SOX9) increase matrix synthesis. Following dose‐of‐action screening, dual...

10.1002/advs.202403227 article EN Advanced Science 2024-05-05

The purpose of the current study was to explore physical activity and screen time status among Chinese adolescents during coronavirus disease (COVID-19) lockdown their association with mood disturbance conflicts parents. A total 1,680 7th 12th grade students enrolled at a large middle-high school located in Southwest China completed an online survey measuring states, activity, time, parents, body height weight. Physical particularly least 150 minutes' duration each week, significantly...

10.3928/02793695-20201104-04 article EN Journal of Psychosocial Nursing and Mental Health Services 2020-11-12

Bone marrow mesenchymal stromal cell-derived exosomes (BMSC-Exos) can recruit stem cells for bone repair, with neovessels serving as the main migratory channel to injury site. However, existing exosome (Exo) delivery strategies cannot reach angiogenesis phase following injury. To that end, an enzyme-sensitive Exo material responds neovessel formation during was designed in present study achieve spatiotemporally controlled release. Herein, matrix metalloproteinase-1 (MMP1) found be highly...

10.1016/j.actbio.2022.11.065 article EN cc-by-nc-nd Acta Biomaterialia 2022-12-06

Abstract Waxy wheat has unique end-use properties; however, its production is limited due mainly to low grain yield compared with non-waxy wheat. In order increase yield, it critical understand the eco-physiological differences in filling between waxy and this study, two cultivars were used investigate starch-associated enzymes processes, sucrose starch dynamics, components, final yield. The results indicated that mean total amylose content, average 1000-kernel weight of lower than those at...

10.1038/s41598-018-22587-0 article EN cc-by Scientific Reports 2018-03-08

Triglyceride glucose (TyG) index and atherogenic of plasma (AIP) are indicators insulin resistance. However, inadequate evidence indicates that the TyG index, AIP, chronic pain linked. Data from National Health Nutrition Examination Survey (NHANES) between 1999 2004 were used. Directed acyclic graphs used to identify 11 potential confounders. The AIP treated as continuous variables in multivariate logistic regression models assess their association with pain. Furthermore, nonlinear...

10.1186/s12944-025-02496-8 article EN cc-by-nc-nd Lipids in Health and Disease 2025-02-25

Abstract This study examined the underlying types of intergenerational relationship and social support network among impaired older adults in China explained how they may influence home- community-based service (HCBS) purchase intentions these individuals. Based on 2018 2020 waves Chinese Longitudinal Aging Social Survey, a total 3,397 (aged ≥ 60 years, with at least one child) were selected. First, we used K-means cluster analysis to identify five families: ‘tight-knit proximal’,...

10.1017/s0144686x25000091 article EN Ageing and Society 2025-04-08

A mixed-methods design was employed to explore classroom teachers' perceptions of using movement in the classroom. Questions on a written survey and interviews were focused gaining understandings knowledge connections between learning, their about as teaching strategy, role schools addressing physical inactivity. Teachers reported lack related but willing learn more add "teaching toolbox" with support training. They also believe that should have increasing activity opportunities youth.

10.18666/tpe-2016-v73-i1-5316 article EN The Physical Educator 2016-01-01

While many American colleges and universities are providing a First Year Experience (FYE) course or program for their first year students, those programs not often customized to take into account international students’ (IS) unique challenges. Using quantitative qualitative methods, this study evaluated FYE that was IS in college setting. Nineteen eight domestic students (DS) who attended classes completed survey; 18 of the 19 were interviewed. Overall, class successful terms helping...

10.32674/jis.v6i1.395 article EN Journal of International Students 2016-01-01

Abstract Rationale: Autoimmune polyendocrine syndrome type 1 (APS-1), also referred as the autoimmune polyendocrinopathy candidiasis-ectodermal dystrophy (APECED), is a rare autosomal inherited disease predominantly among Caucasians from Northern Europe. This very in East Asian population. Patients concerns: Here, we describe case of 15-year-old Chinese boy admitted due to 1-month history intermittent fatigue, nausea, vomiting, and diarrhea. His symptom became worse accompanied with chest...

10.1097/md.0000000000020000 article EN cc-by-nc Medicine 2020-05-01

This study explored the effects of an 8-week peer coaching program on physical activity (PA), diet, sleep, social isolation, and mental health among college students in United States. A total 52 were recruited randomized to (n = 28) or control group 24). The met with a trained coach once week for 8 weeks focusing self-selected wellness domains. Coaching techniques included reflective listening, motivational interviews, goal setting. received handbook. PA, self-efficacy eating healthy foods,...

10.3390/nu15051284 article EN Nutrients 2023-03-04

Chinese female international students (CFIS) have been identified as one of the least physically active groups in United States. In an effort to better understand this situation, study's purpose was examine CFIS American higher education terms meaning they assigned physical activity and facilitators barriers experienced with regard participation.Twenty from a university Northwest region States were recruited interviewed. All interviews conducted Mandarin translated transcribed into English....

10.1080/02701367.2013.813895 article EN Research Quarterly for Exercise and Sport 2013-08-22

Outdoor education programs have been shown to a positive effect on the educational, physical and emotional development of youth. They are increasingly being used foster sense community in schools provide students with learning opportunities related environment. This article describes an integrated outdoor program aimed at increasing activity science knowledge among elementary school children economically disadvantaged urban community. Results from study that was conducted showed levels were...

10.1080/07303084.2017.1390506 article EN Journal of Physical Education Recreation & Dance 2018-01-02

Abstract It has been recognized that myocardial apoptosis is one major factor in the development of heart dysfunction and autophagy shown to influence apoptosis. In previous studies, we reported anti-β 1 -adrenergic receptor autoantibodies (β -AABs) decreased autophagy, but role cardiomyocyte remains unclear. present study, used a β -AAB-immunized rat model investigate We level autophagic flux increased early then an actively model. Rapamycin, mTOR inhibitor, restored presence -AABs....

10.1038/s41419-018-0445-9 article EN cc-by Cell Death and Disease 2018-03-14

It has been recognized that changes in mitochondrial structure plays a key role development of cardiac dysfunction, and autophagy shown to exert maintenance homeostasis effects. Our previous study found anti-β1-adrenergic receptor autoantibodies (β1-AABs) could lead dysfunction along with abnormalities structure. The present tested the hypothesis β1-AABs may induce decline membrane potential (ΔΨm) by suppression autophagy, which contributed dysfunction. Male adult rats were randomized...

10.1371/journal.pone.0081296 article EN cc-by PLoS ONE 2013-11-20

Salvage radiotherapy (SRT) is the first-line treatment for prostate cancer patients with biochemical recurrence following radical prostatectomy, and new specific radiosensitizers are in urgent need to enhance SRT effect. MLN4924 (also known as Pevonedistat), a inhibitor of NEDD8-activating enzyme, has recently entered phase I/II clinical trials several malignancies. By inhibiting cullin neddylation, inactivates Cullin-RING ligases (CRL), which have been validated an attractive...

10.18632/oncotarget.9526 article EN Oncotarget 2016-05-20

The process of acculturation often results in changes the health behavior international students. This study employed an open-ended, qualitative approach attempt to gain in-depth understanding for physical activity, diet, and drinking among Eighteen undergraduate students (average age 19.20, standard deviation 1.21) were interviewed 45-60 min. Most became more physically active after they arrived United States. Facilitators included accessibility, weight management, free time, role modeling....

10.1111/nhs.12232 article EN Nursing and Health Sciences 2015-08-14

Aim and objectives: In the USA, undergraduate students gain more weight in first year college than at any other point their lives. However, factors that predict are unknown. The purpose of this study was to explore predictors among first-year a US over 3-month period. Design: Correlational longitudinal using baseline follow-up self-report survey data. Setting: A private Northeastern USA. Methods: total 110 were invited complete both surveys 3 months apart. examined participants’ knowledge,...

10.1177/0017896919865758 article EN Health Education Journal 2019-07-24
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