A5101606161- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Infectious Aortic and Vascular Conditions
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Disease and Adiposity
- Cardiac electrophysiology and arrhythmias
- Cardiac tumors and thrombi
- Cardiovascular Function and Risk Factors
- Nitric Oxide and Endothelin Effects
- Coronary Artery Anomalies
- Congenital Heart Disease Studies
- Vascular Tumors and Angiosarcomas
- Tracheal and airway disorders
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Metabolism and Genetic Disorders
- Gastric Cancer Management and Outcomes
- Atrial Fibrillation Management and Outcomes
- Cardiac and Coronary Surgery Techniques
- Cardiomyopathy and Myosin Studies
- Pulmonary Hypertension Research and Treatments
- Lymphatic System and Diseases
Teine Keijinkai Hospital
2008-2024
Japan Women's University
2017
Nagatomi Neurosurgical Hospital
2011-2016
Montreal Heart Institute
2015
Virginia Department of Environmental Quality
2015
Kyoto Medical Center
2014
Osaka Medical and Pharmaceutical University
2013
Kyushu University
1980-2006
Nagoya University
2004-2006
Sapporo Medical University
1994-2004
We examined whether coronary risk factors and atherosclerotic lesions in the study artery were associated with impaired endothelium-dependent dilation of resistance arteries. Acetylcholine (ACH) at graded doses (1, 3, 10 30 micrograms/min) papaverine (10 mg) selectively infused into left anterior descending 28 patients, whom was angiographically normal (n = 16) or mild stenosis < 40% 12). Coronary blood flow (CBF) estimated from product mean CBF velocity measured by an intracoronary Doppler...
The relationship between peak isovolumic developed pressure (Pmax) and end-diastolic volume can indicate ventricular contractility. Therefore, we propose a practical method to estimate Pmax from the curve of an ejecting contraction left ventricle. For estimation, first considered ventricle linear time varying hydromotive source (HMP(t)) coupled in series with internal impedance. To formulate HMP(t) Fourier analyzed curves obtained under various conditions six dogs. Since higher order...
Endothelial dysfunction has been implicated as a cause of coronary vasospasm in patients with variant angina. This study aimed to determine if endothelium-dependent vasodilation evoked substance P (SP) was altered at the spastic site where induced by acetylcholine (ACH) It shown that SP evokes no direct effect on vascular smooth muscle excised human arteries. and ACH were infused into arteries nine angina whom arteriograms showed normal or mild atherosclerotic lesions. The vasomotor...
The pathogenesis of histamine-induced coronary spasm was examined angiographically and morphometrically in Göttingen miniature pigs. In five 36 consecutive pigs that were 4 to 5 months age, provoked by the intracoronary administration histamine, left arteries histologically without endothelial denudation (group 1). Endothelial balloon major branch artery performed 31 died during procedure. remaining 26 randomly allotted one two groups, fed a cholesterol-supplemented 2, n = 13) regular...
The outcome of thoracoabdominal or descending aortic aneurysm repair after preoperative demonstration the artery Adamkiewicz (ARM) by magnetic resonance angiography (MRA) was investigated.Between January 2000 and December 2001, 40 consecutive patients who had aneurysms aorta underwent MRA to visualize ARM. Thirty-two replacement aneurysms, 25 (TAAA, 11; TAA, 14) with detection Only intercostal lumbar arteries in which were detected as origin ARM, reattached graft. results operations 11 whom...
Atrial metabolic disturbance contributes to the onset and development of atrial fibrillation (AF). Autophagy plays a role in maintaining cellular energy balance. We examined whether gene expressions related fatty acid metabolism autophagy are altered chronic AF they each other. Right tissue was obtained during heart surgery from 51 patients with sinus rhythm (SR, n = 38) or (n 13). Preoperative fasting serum free-fatty-acid levels were significantly higher patients. The expression binding...
Abstract Epicardial adipose tissue (EAT), a source of adipokines, is metabolically active, but the role EAT mitochondria in coronary artery disease (CAD) has not been established. We investigated association between mitochondrial respiratory capacity, adiponectin concentration EAT, and atherosclerosis. samples were obtained from 25 patients who underwent elective cardiac surgery. Based on angiographycal findings, divided into two groups; (CAD; n = 14) non-CAD (n 11) groups. The capacities...
Effects of leukotriene (LT) C4 and LTD4 on coronary artery spasm in atherosclerotic miniature pigs were examined angiographically. Endothelial balloon denudation the left circumflex was performed 15 Göttingen pigs; 11 fed a 2% cholesterol diet four regular for 3 months. Three months after this denudation, area reduced by 94 +/- 43 5% (p less than .01) denuded nondenuded areas intracoronary administration 10 micrograms/kg histamine pretreatment with 60 mg/kg iv cimetidine. The effects LTC4...
Endothelium-related coronary dilation after balloon denudation was compared with the extent of luminal lining regenerated endothelial cells. Under conditions asepsis, a pair 10-MHz piezoelectric crystals, an electromagnetic flow probe, and cuff occluder were placed on left circumflex artery. Seven to 10 days this instrumentation, dogs anesthetized endothelium removed use catheter. Immediately denudation, dilations following reactive hyperemia (reactive dilation) acetylcholine 3 micrograms/kg...
Primary cardiac sarcomas are extremely rare. Furthermore, the myxofibrosarcomas one of rarest forms sarcomas, and its prognosis is known to be quite poor.This a case 23-year-old man who presented with acute severe congestive heart failure caused by almost complete obstruction mitral valve due large left atrial tumor. The patient required endotracheal intubation before his arrival hospital, underwent an emergent surgical excision tumor had complex shape originated from orifice right upper...
Recent supermicrosurgical techniques have made it possible to anastomose lymph vessels the subdermal venular system. However, because lymphatic fluid is clear and vessel translucent, soft, fragile, with a thinner wall than blood vessels, lymphaticovenular anastomosis demanding technique. One difficulty of identification lumen pass suture into it. This report describes preparatory intravascular stenting technique identify perform accurately. In this technique, we placed 9-0 or 10-0 nylon...
A primary aorto-duodenal fistula (ADF), a rare, spontaneous development of communication between the aorta and duodenum, is disastrous complication an abdominal aortic aneurysm. 73-year-old patient with ADF underwent emergent endovascular aneurysm repair (EVAR), followed by staged omentopexy, without removing stent graft (SG). The received long-term treatment antibiotics, there has been no evidence infection during follow-up period three years. Emergency EVAR coupled may be option for ADF,...
A 36-year-old female patient was admitted to our hospital with a rare case of aneurysm at the origin accessory middle cerebral artery (MCA) manifesting as severe headache and vomiting. Neurological examination did not detect any abnormalities or consciousness disturbance. Computed tomography demonstrated diffuse subarachnoid hemorrhage. Magnetic resonance angiography showed an in horizontal portion left anterior (A(1)). Digital subtraction three-dimensional digital saccular originating...