A5100342527- Traditional Chinese Medicine Analysis
- Cancer-related molecular mechanisms research
- Systemic Lupus Erythematosus Research
- S100 Proteins and Annexins
- Immune cells in cancer
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune Cell Function and Interaction
- Cancer Immunotherapy and Biomarkers
- Cell Adhesion Molecules Research
- Phagocytosis and Immune Regulation
- Pain Mechanisms and Treatments
- Hippo pathway signaling and YAP/TAZ
- Hepatitis B Virus Studies
- Phytochemistry and Biological Activities
- Cancer-related Molecular Pathways
- Autophagy in Disease and Therapy
- Caveolin-1 and cellular processes
- Vaccine Coverage and Hesitancy
- Gastrointestinal motility and disorders
- Parathyroid Disorders and Treatments
- Extracellular vesicles in disease
- Chromatography in Natural Products
- Vascular Malformations Diagnosis and Treatment
- Fungal Biology and Applications
- CAR-T cell therapy research
Nantong University
2023-2024
Affiliated Hospital of Nantong University
2023-2024
Dalian Medical University
2024
Shanghai Stomatological Hospital
2024
Fudan University
2024
Jinzhou Medical University
2017-2024
Sichuan University
2011-2021
Chongqing Medical University
2021
London School of Hygiene & Tropical Medicine
2021
University of Leeds
2021
Colitis-associated cancer (CAC) is a complication of inflammatory bowel disease (IBD) with poor prognosis because it often diagnosed in advanced stages local progression or metastasis. Compared the more common polyp-induced sporadic colorectal (sCRC), CAC has different molecular mechanisms. Toll-like receptor 2 (TLR2) expression not limited to cells related inflammation and immune function. High levels TLR2 tumor tissues (CRC) patients have been reported. This report investigate effects...
Fractalkine (FKN) is a cytokine which plays an important role in atherosclerosis and other inflammatory diseases. Studies have shown that FKN induces integrin-independent leukocyte adhesion to primary endothelial cells under physiological flow conditions. Further, increased expression of has been demonstrated atherosclerotic lesions induced by low shear stress. However, the signal transduction mechanisms involved stress-induced upregulation are not well characterized. In this study, EA.hy926...
The peripheral B cell compartment is heavily disturbed in systemic lupus erythematosus (SLE), but whether cells develop aberrantly the bone marrow (BM) largely unknown.
In mainland China, HPV vaccines have been available to the public. However, only a few related studies among health care providers, as key information were reported although public concerns on still exist. this study, we aim assess knowledge of HPV, its vaccines, and attitudes toward three most important groups providers in Western China.This was cross-sectional questionnaire-based study. Health including obstetrician-gynecologists (OB-GYNs), pediatricians, immunization service China...
Emerging evidence indicates that gut dysbiosis is involved in the pathogenesis of visceral hypersensitivity (VH). However, how microbiota contributes to development VH unknown. Here, we sought examine signal transduction pathways from dorsal root ganglion (DRG) responsible for this. Therefore, abdominal withdrawal reflex (AWR) scores, fecal output, water content, and total gastrointestinal transit time (TGITT) were assessed Con rats, rats treated with NaB, VSL#3. Fecal its metabolite...
Down-regulated parafibromin is positively linked to the pathogenesis of parathyroid, lung, breast, ovarian, gastric and colorectal cancers. Here, we found that wild-type (WT) overexpression suppressed proliferation, tumor growth, induced cell cycle arrest apoptosis in cancer cells (p<0.05), but it was converse for mutant-type (MT, mutation nucleus localization sequence) (p<0.05). Both WT MT transfectants inhibited migration invasion, caused better differentiation (p<0.05) cells. showed...
In systemic lupus erythematosus (SLE), neutrophil dysregulation and extracellular traps (NETs) formation contribute to disease pathogenesis, potentially worsening the autoimmune response. Although research indicates NETs' involvement in various conditions, their relationship with regulatory T cells (Tregs) SLE remains elusive. this study, vivo experiments were involved administering NET injections C57BL/6 MRL/Ipr mice. vitro, a co-culture system facilitated interaction between Tregs NETs....
Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease characterized by dysregulation in both innate adaptive immunity. Polarization of macrophages into M1/M2 affects the development lupus. Exosomes-miRNA plays crucial role progression. This study aims to explore mechanism circulating exosomes participating pathogenesis SLE seek new therapeutic targets. Plasma derived-exosomes from patients accelerated progression polarization kidney MRL/lpr mice. Exosomes were taken...