A5014380244- Health disparities and outcomes
- Frailty in Older Adults
- Stress Responses and Cortisol
- Geriatric Care and Nursing Homes
- Palliative Care and End-of-Life Issues
- Nutrition and Health in Aging
- Health Systems, Economic Evaluations, Quality of Life
- Health, psychology, and well-being
- Migration, Aging, and Tourism Studies
- Aging and Gerontology Research
- Childhood Cancer Survivors' Quality of Life
- Cancer survivorship and care
- Optimism, Hope, and Well-being
- Global Health Care Issues
- Tryptophan and brain disorders
- Psychological Well-being and Life Satisfaction
- Cancer-related cognitive impairment studies
- Balance, Gait, and Falls Prevention
- Stroke Rehabilitation and Recovery
- Heart Rate Variability and Autonomic Control
- Cardiac Health and Mental Health
- Menstrual Health and Disorders
- Musculoskeletal pain and rehabilitation
- Healthcare and Venom Research
- Chronic Disease Management Strategies
University of Rochester Medical Center
2014-2024
University of Rochester
2015-2024
Institute on Aging
2018-2019
Johns Hopkins University
2005-2015
Medical College of Wisconsin
2015
Temple University
2015
The Centers
2013
Miriam Hospital
2013
University of California, San Diego
2013
Johns Hopkins Medicine
2012
Background.Frailty assessment provides a means of identifying older adults most vulnerable to adverse outcomes. Attention frailty in clinical practice is more likely with better understanding its prevalence and associations patient characteristics. We sought provide national estimates people.
<h3>Background:</h3> Frailty is a common risk factor for morbidity and mortality in older adults. Although both low socioeconomic status (SES) frailty are important sources of vulnerability, there limited research examining their relationship. A study was undertaken to determine (1) the extent which SES associated with increased odds (2) whether race frailty, independent SES. <h3>Methods:</h3> cross-sectional analysis Women's Health Aging Studies using multivariable ordinal logistic...
To determine effect size and acceptability of a multicomponent behavior home repair intervention for low-income disabled older adults.Prospective randomized controlled pilot trial.Participants' homes.Forty adults with difficulties in one or more activities daily living (ADLs) two instrumental (IADLs).The Community Aging Place, Advancing Better Living Elders (CAPABLE), coordinated occupational therapy, nursing, handyman visits, was compared attention-control visits. The consisted up to six...
Few studies have addressed changes in physical activity participation over time among the elderly. The authors hypothesized that there were distinct trajectories of level and identifiable predictors such trajectories, as well maintenance regular activity, even below recommended levels, was associated with lower mortality risk. Using longitudinal data (1994–2009) from 433 initially high-functioning older women aged 70–79 years at baseline, a joint latent class survival mixture model...
Activity is associated with health among older adults yet adults' favorite activities have rarely been investigated. We analyzed the community dwelling, cognitively-intact sample of NHATS, a nationally representative ≥65, who had named their (N = 5247). Logistic regression models estimated odds choosing physical activity controlling for demographics, self-rated health, and disability. For all ages, four top five most common were active: walking/jogging (14%), outdoor maintenance (13%),...
We describe the decision-making process used by emergency medical services (EMS) providers in order to understand how 1) injured patients are evaluated prehospital setting; 2) field triage criteria applied in-practice; and 3) selection of a destination hospital is determined. conducted separate focus groups with advanced basic life support from rural urban/suburban regions. Four exploratory were identify overarching themes five additional confirmatory verify initial group findings provide...
Importance Older adults with advanced cancer are less likely to tolerate treatment cytotoxic chemotherapy compared younger patients due their aging-related conditions. Hence, oncologists sometimes opt employ primary modifications (deviation from standard of care) during the first cycle chemotherapy. Objective To examine association between modification and tolerability in older who were starting new palliative regimens. Design, Setting, Participants This cohort study was a secondary analysis...
We use a population-based representative sample of older Taiwanese to investigate links between respondents' perceived levels stress and broad set biological measures. These biomarkers were collected at single time (2000) reflect sympathetic nervous system (SNS)-activity, hypothalamo-pituitary-adrenal (HPA)-activity, immune function, cardiovascular metabolic pathways. model the relationship (1) extreme values for each 16 individual indicators; (2) measure cumulative physiological...
We investigate how biological markers of individual responses to stressful experiences are associated with profiles physical and mental functioning in a national sample middle-aged elderly Taiwanese. Data come from population-based Taiwanese 2000. The data combine rich measures self-reported information on health. Grade membership methods used summarize functional status, multinomial logit models provide the association between function. analysis identifies significant associations...
Frailty involves decrements in many physiologic systems, is prevalent older ages, and characterized by increased vulnerability to disability mortality. It yet unclear how this geriatric syndrome relates a preclinical cumulative marker of multisystem dysregulation. The purpose study was evaluate whether allostatic load (AL) associated with the frailty community-dwelling women.We examined cross-sectional relationship between AL validated measure baseline examination two complementary...
Recommended levels of physical activity may represent challenging targets for many older adults at risk disability, leading to the importance evaluating whether low-intensity is associated with health benefits. We examined cross-sectional association between walking (<100 steps/min) and function in a group adults. Participants ( N = 187; age 66.8; 91.4% African American; 76.5% female) wore StepWatch Activity Monitor measure components activity. Only 7% participants met guidelines...
<h3>Importance</h3> A poor prognostic understanding regarding curability is associated with lower odds of hospice use among patients cancer. However, the association between or discordance and health care older adults advanced incurable cancers not well characterized. <h3>Objective</h3> To evaluate patient-oncologist hospitalization cancers. <h3>Design, Setting, Participants</h3> This was a post hoc secondary analysis cluster randomized clinical trial that recruited from October 29, 2014, to...
Background This study examined the correlation of classroom ventilation (air exchanges per hour (ACH)) and exposure to CO 2 ≥1,000 ppm with incidence SARS-CoV-2 over a 20-month period in specialized school for students intellectual developmental disabilities (IDD). These were at higher risk respiratory infection from due challenges tolerating mitigation measures (e.g. masking). One in-school measure proposed help mitigate schools is increased ventilation. Methods We established...
Objectives.Studies of late-life disablement typically address the role advancing age as a factor in developing disability, and some cases have pointed out importance time to death (TTD) understanding changes functioning. However, few studies addressed both factors simultaneously, none dealt satisfactorily with problem missing data on TTD panel studies.
Participation in social and community activities that require leaving one's home is important to older adults; however, many adults have difficulty or are unable leave their dwellings, little known from national samples about issues related remaining active outside the barriers faced by these adults. We used National Health Aging Trends Study, a nationally representative study of (n = 7197), understand following: (1) importance homebound semi-homebound place on involvement activities, (2)...
Few studies focus on "preclinical" warning signs associated with mortality. In this article, we investigate associations between all-cause mortality and two clusters of biological risk factors: (i) standard clinical measures related to cardiovascular disease metabolic function; (ii) nonclinical pertaining hypothalamic-pituitary-adrenal axis activity, sympathetic nervous system inflammatory response.Data come from the 2000 Social Environment Biomarkers Aging Study, a national sample Taiwanese...
Abstract Introduction “Frailty” has attracted attention for its promise of identifying vulnerable older adults, hence potential use to better tailor geriatric health care. There remains substantial controversy, however, regarding nature and ascertainment. Recent years have seen a proliferation frailty assessment methods. We argue that the development assessments should be grounded in “validation”—the process substantiating measurement accurately precisely measures what it intends, identify...