A5047004084- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Moringa oleifera research and applications
- Medicinal Plants and Neuroprotection
- Cholinesterase and Neurodegenerative Diseases
- Essential Oils and Antimicrobial Activity
- Ginger and Zingiberaceae research
- Chemotherapy-induced organ toxicity mitigation
- Antioxidant Activity and Oxidative Stress
- African Botany and Ecology Studies
- Pharmacological Effects of Natural Compounds
- Nigella sativa pharmacological applications
- Bee Products Chemical Analysis
- Seed and Plant Biochemistry
- Pomegranate: compositions and health benefits
- Hibiscus Plant Research Studies
- Garlic and Onion Studies
- Piperaceae Chemical and Biological Studies
- Agricultural pest management studies
- Biochemical Analysis and Sensing Techniques
- Pharmacological Effects of Medicinal Plants
- Phytochemistry and Biological Activities
- Phytoestrogen effects and research
- Advances in Cucurbitaceae Research
- Botanical Research and Applications
Federal University of Technology
2015-2024
Universidade Federal de Santa Maria
2015-2019
Osun State University
2011-2012
Abstract Background: Chlorogenic acid is a major phenolic compound that forms substantial part of plant foods and an ester caffeic quinic acid. However, the effect structures both chlorogenic acids on their antioxidant antidiabetic potentials have not been fully understood. Thus, this study sought to investigate compare interaction with α-amylase α-glucosidase (key enzymes linked type 2 diabetes) activities in vitro. Methods: The inhibitory was evaluated. Thereafter, as typified by...
Caffeic acid (CAA) and chlorogenic (CHA) are important members of hydroxycinnamic with natural antioxidant cardio-protective properties. The present study aimed to determine the effect CAA CHA on systolic blood pressure, heart rates (HR) as well activity angiotensin-1-converting enzyme (ACE), acetylcholinesterase (AChE), butrylcholinesterase (BChE) arginase in cyclosporine-induced hypertensive rats. Experimental rats were distributed into 7 groups (n = 6): normotensive control rats; (induced...
This study was designed to determine the antioxidant properties and inhibitory effects of extract from Moringa oleifera leaves on angiotensin-I-converting enzyme (ACE) arginase activities in vitro. The prepared phenolic (total phenols flavonoid) contents, radical (nitric oxide (NO), hydroxyl (OH)) scavenging abilities, Fe(2+)-chelating ability were assessed. Characterization constituents done via high performance liquid chromatography-diode array detection (HPLC-DAD) analysis. Furthermore,...
Summary Maize varieties (yellow and white) were roasted for 17 min; allowed to cool, later milled into powder. The nutritional evaluation (proximate composition, mineral antinutrient content determination) antioxidant properties investigation (reducing power, free radicals scavenging ability Fe 2+ chelating ability) of the product was subsequently carried out. result study revealed that roasting caused a significant increase ( P < 0.05) in crude fat, carbohydrate, Ca, Na, Mg Zn content....
The effect of fermentation on the polyphenol distribution and antioxidant activity four underutilized legumes [Cajanus cajan L. Millsp (Pigeon pea), Vigna subterranea Verdc (Bambara groundnut), Sphenostylis stenocarpa Harms (African yam bean), Phaseolus vulgaris (Kidney bean)] were investigated. beans cooked (12 h), soaked in boiled water dehulled, then again (2 h). cotyledons drained, wrapped jute sacks left to ferment at 37°C (4 days) produce condiments. free bound phenolic compounds...
Moringa oleifera leaf is a popular green leafy vegetable which has found its usefulness in the preparation of traditional stews and soups. Like most are not around year-round, usually dried pulverized for storage easier handling, despite popularity this processing technique, there dearth information on how drying affects health-promoting properties leaves. Hence, study sought to investigate effect some methods (freeze-drying, sun, air oven drying) phytoconstituents, antioxidant properties,...
This study sought to investigate the inhibitory effect of aqueous extracts two varieties (red and white) Hibiscus sabdariffa (Roselle) calyces on carbohydrate hydrolyzing enzymes (α-amylase α-glucosidase), with aim providing possible mechanism for their antidiabetes properties. Aqueous were prepared (1:100 w/v) supernatant used analysis. The caused inhibition α-amylase α-glucosidase activities in vitro.The IC(50) revealed that red variety (25.2 μg/mL) exhibited higher activity than white...
Spices are used in soup preparation many homes and serve as ingredients the of several traditional delicacies endowed with natural antioxidants such polyphenols. The aim this study is to evaluate effect aqueous extract garlic, white onion, purple onion on angiotensin-converting enzyme, α-amylase, α-glucosidase activity vitro determine their antioxidant properties via various assays OH*, Fe2+ chelation, 2, 2'-azino-bis 3-ethylbenzothiazoline-6-sulphonic acid (ABTS) radical-scavenging assays....
Abstract Background: Avocado pear ( Persea americana Mill.) leaves and seeds are used in traditional medicine for the treatment/management of Alzheimer disease (AD); however, information on mechanism actions is limited. This study sought to investigate effect P. leaf seed aqueous extracts some enzymes linked with AD (acetylcholinesterase [AChE] butyrylcholinesterase [BChE] activities) their antioxidant potentials vitro. Methods: The inhibitory effects AChE BChE activities (inhibition Fe 2+ -...
Ginger has reportedly been used in folk medicine for the management and prevention of hypertension other cardiovascular diseases. Therefore, this study sought to investigate inhibitory effect aqueous extracts two varieties ginger on a key enzyme linked (angiotensin I–converting [ACE]), pro-oxidants [Fe2+ sodium nitroprusside (SNP)] which have shown induce lipid peroxidation rat's isolated heart vitro. Aqueous (0.05 mg/mL) red (Zingiber officinale var. Rubra) white Roscoe) were prepared...
Raphiodon echinus (R. echinus) is used in Brazilian folk medicine for the treatment of inflammation, coughs, and infectious diseases. However, no information available on potential antioxidant, cytotoxicity genotoxicity this plant. In study, polyphenolic constituents, antioxidant capacity toxic effects aqueous ethanolic extracts R. human erythrocytes leukocytes were investigated first time. showed presence Gallic, chlorogenic, caffeic ellagic acids, rutin, quercitrin quercetin. Aqueous...