A5038492645- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Obstructive Sleep Apnea Research
- Cardiac electrophysiology and arrhythmias
- Neuroscience of respiration and sleep
- Cardiac Structural Anomalies and Repair
- Tracheal and airway disorders
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular and Diving-Related Complications
- Congenital Heart Disease Studies
- Voice and Speech Disorders
- Lanthanide and Transition Metal Complexes
- Cardiovascular Syncope and Autonomic Disorders
- Advanced MRI Techniques and Applications
- Heart Rate Variability and Autonomic Control
- Dysphagia Assessment and Management
- Gene expression and cancer classification
- Antibiotics Pharmacokinetics and Efficacy
- Respiratory Support and Mechanisms
- Pneumonia and Respiratory Infections
- Cardiac and Coronary Surgery Techniques
- Drug Transport and Resistance Mechanisms
- Ultrasound and Hyperthermia Applications
Heart and Diabetes Center North Rhine-Westphalia
2013-2023
Herford Hospital
2020-2022
Asklepios Klinik St. Georg
2020
Ruhr University Bochum
2010-2017
University Hospitals of the Ruhr-University of Bochum
2014
LWL-Universitätsklinikum Bochum
2014
Klinikum Coburg
2006-2012
Cegep de Sainte Foy
2012
University of Utah
2006
Freie Universität Berlin
1997
Catheter ablation for ventricular tachycardia (VT) reduces the recurrence of VT in patients with implantable cardioverter-defibrillators (ICDs). The appropriate timing and its effects on mortality heart failure progression remain a matter debate. In life-threatening arrhythmias necessitating ICD implantation, we compared outcomes preventive (undertaken before implantation to prevent shocks VT) deferred after 3 VT. BERLIN study (Preventive Ablation Ventricular Tachycardia Patients With...
Oesophageal injury has been reported with delivery of radio-frequency lesions at the left atrium posterior wall in catheter ablation procedures for atrial fibrillation (AF). In this observational study we prospectively assessed endoscopical oesophageal changes after pulmonary vein antrum isolation (PVAI) patients presenting treatment AF. Twenty eight (18 men; mean age 55 ± 11 years) were ablated using either a cooled-tip or an 8 mm tip catheter. Endoscopy oesophagus was performed 24 h PVAI....
The aim of this study was to evaluate chronic, transvenous, unilateral phrenic nerve stimulation treat central sleep apnea (CSA) in a prospective, multicenter, nonrandomized study. CSA occurs predominantly patients with heart failure and increases the risk for morbidity mortality. Established therapies are lacking, those available limited by poor patient adherence. Fifty-seven underwent baseline polysomnography followed transvenous system implantation follow-up. Feasibility assessed success...
Periodic breathing with central sleep apnoea (CSA) is common in heart failure patients and associated poor quality of life increased risk morbidity mortality. We conducted a prospective, non-randomized, acute study to determine the feasibility using unilateral transvenous phrenic nerve stimulation for treatment CSA patients. Thirty-one from six centres underwent attempted lead placement. Of these, 16 qualified undergo two successive nights polysomnography—one night one without stimulation....
Cardiac resynchronization therapy (CRT) is sometimes complicated by elevated pacing thresholds and phrenic nerve stimulation (PNS), both of which may require that the coronary sinus lead be repositioned. The purpose this study was to evaluate performance a novel quadripolar electrode cardiac therapy-defibrillator (CRT-D) device enables electrical repositioning, potentially obviating reposition procedure. Patients indicated for CRT were enrolled received CRT-D (Quartet®model 1458Q Promote Q®;...
Predictors of AF Recurrence After Cryoballoon PVI. Introduction: In patients with atrial fibrillation (AF) undergoing pulmonary vein isolation, cryoballoon technique (cryoPVI) has been adopted in many centers. This study aimed to evaluate predictors recurrence including impact sleep‐disordered breathing (SDB). Methods and Results: 82 consecutively assigned cryoPVI cardiorespiratory screening for SDB, assessment medical history, ECG, echocardiography, standard laboratory measurement, blood...
Cheyne‐Stokes Respiration and Arrhythmias Objective This study aimed to investigate whether adequate treatment of respiration (CSR) reduces the risk arrhythmic events in patients with chronic heart failure (CHF). Methods A cohort 403 registry CHF (LVEF≤45%, NYHA‐class≥2) implanted cardioverter‐defibrillator devices (ICD) was studied. They underwent overnight polygraphy, 221 having mild or no CSR (apnea‐hypopnea index [AHI]<15/h), 182 moderate severe (AHI>15/h). Latter ones were offered...
cryoballoon ablation has been adopted for pulmonary vein (PV) isolation (PVI) in many centers. Complete occlusion of PV by an adequately sized balloon is crucial effectiveness cryoenergy delivery. The aim this study was to evaluate intracardiac echocardiography (ICE) as alternative imaging technique compared angiographic PVI.a total 75 PVs were treated 22 patients (61 ± 13 years, 17 male) undergoing drug refractory paroxysmal atrial fibrillation. Decision adequate size based on diameters the...
The population treated with cryoballoon (CB) ablation is relatively young, and radiation protection of major importance. We aimed to demonstrate that exposure can be markedly reduced by intracardiac echocardiography (ICE) optimized settings the X-ray system. analysed 100 patients undergoing CB pulmonary vein isolation (PVI) for treatment paroxysmal atrial fibrillation. In 50 consecutive (25 male, 59 ± 13 years; Group 1), we used ICE, skipped PV angiography prior inflation, avoided...
Studies have shown that remote magnetic navigation is safe and effective for ablation of atrial arrhythmias, although optimal outcomes often require frequent manual manipulation a circular mapping catheter. The Vdrive robotic system ('Vdrive') was designed catheters to enable fully procedure. This study details the first human clinical experience with catheter in left atrium.This prospective, multi-centre, non-randomized consecutive case series included patients presenting arrhythmias....
Background Sleep‐disordered breathing (SDB) and Cheyne‐Stokes respiration (CSR) are associated with shorter survival in patients heart failure. A novel treatment method for this patient group is unilateral phrenic nerve stimulation by the remedē® system (Respicardia Inc., Minnetonka, MN, USA), a transvenously implantable neurostimulation device, which has recently been studied large randomized, controlled trial. Previous literature shown efficacy safety of first‐generation but hardly any...
Background: Pulmonary vein antrum isolation (PVAI) is a potentially curative, nonpharmacologic treatment of atrial fibrillation (AF). Several procedural complications have been described, including esophageal wall lesions ranging from erythema and esophagitis, necrosis ulcer, to atrio‐esophageal fistula. We prospectively studied changes in acid levels before after PVAI. Methods: performed 24‐hour pH‐metry 1.3 ± 1.6 days PVAI, 25 patients (mean age = 62 12 years, 17 men) with symptomatic AF....
Pulmonary vein isolation (PVI) using cryoballoon ablation (CBA) is an established procedure for treating symptomatic paroxysmal and persistent atrial fibrillation (AF). The safety efficacy of PVI performed at community hospitals are unknown. We aimed to determine the acute CBA with limited annual case numbers.This registry study included 1004 consecutive patients who had (n = 563) or AF 441) from January 2019 September 2020 20 hospitals. Each hospital fewer than 100 CBA-PVI procedures/year...
Image integration of three-dimensional (3D) reconstructions left atrial (LA) and pulmonary vein (PV) anatomy into electroanatomical mapping (EAM) plays a major role in fibrillation (AF) ablation. Point-by-point EAM is commonly used for registration imported LA PV anatomy. We aimed to assess the accuracy intraprocedural rotational angiography-based imaging registered by spatial reconstruction intracardiac echocardiography (ICE) patients undergoing AF Twenty-two (11 males, 66 ± 12 years) were...
AimsRotational angiography (RA) of the coronary sinus (CS) provides more anatomical insights compared with static angiographies. We evaluated intraprocedural three-dimensional (3D) CS reconstruction (RC) based on RA, using syngo® DynaCT Cardiac to guide lead implantation.
Six months after subcutaneous implantable cardioverter defibrillator (S-ICD) implantation a 26-year-old Brugada patient presented because of beeping tone emitted by his device. Chest X-ray displayed two functionless transvenous shock leads and the S-ICD system with lead fracture. During revision procedure, extensive preparation from unexpectedly firm surrounding fibrous tissue encapsulating was necessary before it could be removed, new implanted. This is first report an exchange due to very...
Cardiac resynchronization therapy (CRT) using left- (LV) or biventricular pacing is widely applied in selected heart failure patients. However, transvenous LV-lead placement into coronary sinus (CS) branches can be challenging. A 77-year-old female patient with New York Heart Association class III symptoms due to dilated cardiomyopathy [LV ejection fraction (LVEF): 10%, QRS-duration: 150 ms], despite optimal medical treatment presented for CRT. Coronary angiograms were performed after CS...