Daniel Antunes Maciel Villela

ORCID: 0000-0001-8371-2959
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About
Contact & Profiles
Research Areas
  • COVID-19 epidemiological studies
  • Mosquito-borne diseases and control
  • Malaria Research and Control
  • Education during COVID-19 pandemic
  • SARS-CoV-2 and COVID-19 Research
  • Vaccine Coverage and Hesitancy
  • Viral Infections and Outbreaks Research
  • Data-Driven Disease Surveillance
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Viral Infections and Vectors
  • Zoonotic diseases and public health
  • COVID-19 Pandemic Impacts
  • Caching and Content Delivery
  • COVID-19 Clinical Research Studies
  • Insect symbiosis and bacterial influences
  • Healthcare Regulation
  • Network Traffic and Congestion Control
  • Science and Education Research
  • Software-Defined Networks and 5G
  • Evolution and Genetic Dynamics
  • Healthcare during COVID-19 Pandemic
  • Peer-to-Peer Network Technologies
  • Insect and Pesticide Research
  • Global Public Health Policies and Epidemiology
  • Health, Nursing, Elderly Care

Fundação Oswaldo Cruz
2016-2025

Princeton University
2024

Impact
2023

Secretaria Municipal de Saúde
2022

Faculdades Oswaldo Cruz
2022

Universidade Federal Rural do Rio de Janeiro
2022

Ordem dos Médicos
2021

Interface (United States)
2021

Ministério Público
2021

Walker (United States)
2021

que o trabalho original seja corretamente citado.Coronavírus são RNA vírus causadores de infecções respiratórias em uma variedade animais, incluindo aves e mamíferos 1 .Sete coronavírus reconhecidos como patógenos humanos.Os sazonais estão geral associados a síndromes gripais.Nos últimos 20 anos, dois deles foram responsáveis por epidemias mais virulentas síndrome respiratória aguda grave (SRAG).A epidemia SARS emergiu Hong Kong (China), 2003, com letalidade aproximadamente 10% 2 do Oriente...

10.1590/0102-311x00019620 article PT cc-by Cadernos de Saúde Pública 2020-01-01

Traditional vector control approaches such as source reduction and insecticide spraying have limited effect on reducing Aedes aegypti population. The endosymbiont Wolbachia is pointed a promising tool to mitigate arbovirus transmission has been deployed worldwide. Models predict rapid increase the frequency of Wolbachia-positive Ae. mosquitoes in local settings, supported by cytoplasmic incompatibility (CI) high maternal rate associated with wMelBr strain.Wolbachia strain was released for 20...

10.1371/journal.pntd.0007023 article EN cc-by PLoS neglected tropical diseases 2019-01-08

In this paper we present a programmable networking model that provides common framework for understanding the state-of-the-art in networks. A number of projects are reviewed and discussed against set network characteristics. We believe important innovations creating paradigm shift leading to higher levels programmability. These include separation between transmission hardware control software, availability open interfaces, accelerated virtualization infrastructure, rapid creation deployment...

10.1145/505733.505735 article EN ACM SIGCOMM Computer Communication Review 1999-04-01

The study aims to describe patients hospitalized for severe acute respiratory illness (SARI) due COVID-19 (SARI-COVID) in Brazil according demographic characteristics and comorbidities up the 21st Epidemiological Week of 2020. aimed compare these with those SARI influenza 2019/2020 (SARI-FLU) Brazilian general population. proportions characteristics, comorbidities, pregnant postpartum women among SARI-COVID SARI-FLU were obtained from SIVEP-Gripe database, estimates population projections...

10.1590/0102-311x00149420 article EN cc-by Cadernos de Saúde Pública 2020-01-01

Brazil detected community transmission of COVID-19 on March 13, 2020. In this study we identified which areas in the country were most vulnerable for COVID-19, both terms risk arrival cases, sustained and their social vulnerability. Probabilistic models used to calculate probability spread from São Paulo Rio de Janeiro, initial hotspots, using mobility data pre-epidemic period, while multivariate cluster analysis socio-economic indices was done identify with similar The results consist a...

10.1371/journal.pone.0238214 article EN cc-by PLoS ONE 2020-09-18

Background The symbiotic bacterium Wolbachia is currently being trialled as a biocontrol agent in several countries to reduce dengue transmission. can invade and spread infect all individuals within wild mosquito populations, but requires high rate of maternal transmission, strong cytoplasmic incompatibility low fitness costs the host order do so. Additionally, extensive differences climate, field-release protocols, urbanization level human density amongst sites where this has been deployed...

10.1371/journal.pntd.0003689 article EN cc-by PLoS neglected tropical diseases 2015-04-23

Resumo: A vigilância de síndrome respiratória aguda grave (SRAG) no Brasil visa a caracterizar circulação dos vírus Influenza e B em casos hospitalizados óbitos, tendo sido ampliada 2012 para incluir outros respiratórios. COVID-19 foi detectada pela primeira vez na 9ª semana epidemiológica 2020 o teste SARS-CoV-2 incluído protocolo partir da 12ª epidemiológica. O objetivo deste estudo investigar padrão hospitalizações por SRAG país após entrada do SARS-CoV-2, comparando perfil temporal,...

10.1590/0102-311x00070120 article PT cc-by Cadernos de Saúde Pública 2020-01-01

One difficulty for real‐time tracking of epidemics is related to reporting delay. The delay may be due laboratory confirmation, logistical problems, infrastructure difficulties, and so on. ability correct the available information as quickly possible crucial, in terms decision making such issuing warnings public local authorities. A Bayesian hierarchical modelling approach proposed a flexible way correcting delays quantify associated uncertainty. Implementation model fast use integrated...

10.1002/sim.8303 article EN cc-by Statistics in Medicine 2019-07-10

Mathematical modelling and statistical inference provide a framework to evaluate different non-pharmaceutical pharmaceutical interventions for the control of epidemics that has been widely used during COVID-19 pandemic. In this paper, lessons learned from previous are highlight challenges future pandemic control. We consider availability use data, as well need correct parameterisation calibration model frameworks. discuss arise in describing distinguishing between interventions, within...

10.1016/j.epidem.2022.100546 article EN cc-by-nc-nd Epidemics 2022-02-11

Brazil started the COVID-19 mass vaccination in January 2021 with CoronaVac and ChAdOx1, followed by BNT162b2 Ad26.COV2.S vaccines. By end of 2021, more than 317 million vaccine doses were administered adult population. This study aimed at estimating effectiveness primary series booster shots protecting against severe cases deaths during first year vaccination.A cohort dataset over 158 records linked from official national registries was analyzed via a mixed-effects Poisson model, adjusted...

10.1016/j.lana.2023.100465 article EN cc-by-nc-nd The Lancet Regional Health - Americas 2023-03-13

Server providers that support e-commerce applications as a service for multiple Web sites traditionally use tiered server architecture. This architecture includes an application tier to process requests dynamically generated content. How this is provisioned can significantly impact provider's profit margin. In article we study methods provision servers in the serving increase profits. First, examine actual traces of request arrivals site, and show arrival effectively Poisson. Next, construct...

10.1145/1189740.1189747 article EN ACM Transactions on Internet Technology 2007-02-01

SUMMARY Zika virus infection was declared a public health emergency of international concern in February 2016 response to the outbreak Brazil and its suspected link with congenital anomalies. In this study, we use notification data disease natural history parameters estimate basic reproduction number ( R 0 ) Rio de Janeiro, Brazil. We also obtain estimates dengue from time series cases outbreaks registered 2002 2012 city, when DENV-3 DENV-4 serotypes, respectively, had just emerged. Our for...

10.1017/s0950268817000358 article EN Epidemiology and Infection 2017-02-27

Mosquitoes that carry Wolbachia endosymbionts may help control the spread of arboviral diseases, such as dengue, Zika and chikungunya. frequencies systematically increase only when frequency-dependent advantage due to cytoplasmic incompatibility exceeds frequency-independent costs, which be intrinsic and/or can associated with genetic background into are introduced. Costs depend on field conditions environmental pesticide load. Introduced mosquitoes need adequate protection against...

10.1038/s41598-019-56766-4 article EN cc-by Scientific Reports 2020-01-09

A nationwide Severe Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) vaccination campaign was initiated in Brazil January 2021 with CoronaVac (Sinovac Biotech) and ChAdOx1 nCoV-19 (AstraZeneca) followed by BNT162b2 mRNA (Pfizer–BioNTech) Ad26.COV2.S (Johnson & Johnson–Janssen) vaccines. Here we provide estimates of the number severe cases deaths due to coronavirus disease (COVID-19) averted during first year mass Brazil. Data on COVID-19 COVID-19-related illness death were obtained from...

10.1016/j.lana.2022.100418 article EN cc-by-nc-nd The Lancet Regional Health - Americas 2022-12-22

The estimation of parameters and model structure for informing infectious disease response has become a focal point the recent pandemic. However, it also highlighted plethora challenges remaining in fast robust extraction information using data models to help inform policy. In this paper, we identify discuss four broad paradigm relating modelling, namely Uncertainty Quantification framework, estimation, model-based inference prediction, expert judgement. We postulate priorities methodology...

10.1016/j.epidem.2022.100547 article EN cc-by-nc-nd Epidemics 2022-02-10

Abstract Background As malaria endemic countries strive towards elimination, intensified spatial heterogeneities of local transmission could undermine the effectiveness traditional intervention policy. Methods The dynamic nature large-scale and long-term heterogeneity across Brazilian Amazon basin were explored by (1) exploratory analysis Brazil’s rich clinical reporting database from 2004 to 2018, (2) adapting Gini coefficient study distribution cases in region. Results declined, increased...

10.1186/s12936-021-03614-4 article EN cc-by Malaria Journal 2021-02-12

Background Despite recent intensification of control measures, Plasmodium vivax poses a major challenge for malaria elimination efforts. Liver-stage hypnozoite parasites that cause relapsing infections can be cleared with primaquine; however, poor treatment adherence undermines drug effectiveness. Tafenoquine, new single-dose treatment, offers an alternative option preventing relapses and reducing transmission. In 2018, over 237,000 cases were reported to the Brazilian health system, which...

10.1371/journal.pmed.1003535 article EN cc-by PLoS Medicine 2021-04-23

Malaria transmission modelling has demonstrated the potential impact of semiquantitative glucose-6-phosphate dehydrogenase (G6PD) testing and treatment with single-dose tafenoquine for Plasmodium vivax radical cure but not investigated associated costs. This study evaluated cost-effectiveness P. after G6PD using a model.

10.1371/journal.pmed.1004255 article EN cc-by PLoS Medicine 2024-01-09

This study introduces a model for developing dengue vaccine program children aged 10-14 in Rio de Janeiro, Brazil. We simulate spread and vaccination impacts over three years, focusing on efficacies, timing, stochastic rates within SIRS-V framework. Our findings highlight the importance of efficacy timing reducing infections managing outbreaks. Even with lower efficacy, early significantly reduces infection peaks delays epidemic onset. While there are discrepancies actual data, suggesting...

10.5540/03.2025.011.01.0379 article EN Proceeding Series of the Brazilian Society of Computational and Applied Mathematics 2025-01-20

Background We quantified the national- and state-level burden of COVID-19 in Brazil its states during 2020 contrasted it to from other causes disease injury. Methods used national surveillance data on cases, hospitalisations deaths between February/2020 December/2020. calculated disability-adjusted life years (DALYs) based consensus model methods developed by European Burden Disease Network, which includes mild moderate, severe, critical long covid due COVID-19. DALYs estimates Global...

10.1371/journal.pone.0319941 article EN cc-by PLoS ONE 2025-03-27
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