A5018506651- Plant Molecular Biology Research
- Plant nutrient uptake and metabolism
- Building Energy and Comfort Optimization
- Plant Reproductive Biology
- Plant tissue culture and regeneration
- Photosynthetic Processes and Mechanisms
- Plant Gene Expression Analysis
- Advanced Topics in Algebra
- Estrogen and related hormone effects
- Advanced Algebra and Geometry
- Cancer-related Molecular Pathways
- Microtubule and mitosis dynamics
- Light effects on plants
- Menopause: Health Impacts and Treatments
- Sustainable Building Design and Assessment
- Building energy efficiency and sustainability
- Advanced Operator Algebra Research
- Ubiquitin and proteasome pathways
- Integrated Energy Systems Optimization
- Folklore, Mythology, and Literature Studies
- Hernia repair and management
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Liver Disease Diagnosis and Treatment
- RNA and protein synthesis mechanisms
- Phytoestrogen effects and research
Institute of Plant Biology
2015-2025
HUN-REN Szegedi Biológiai Kutatóközpont
2015-2025
Hungarian Academy of Sciences
1997-2024
Research Centre for the Humanities
2021-2023
Hungarian Research Network
2021-2022
Institute of Ethnology
2021
Czech Academy of Sciences, Institute of Ethnology
2021
Budapest University of Technology and Economics
2014-2020
University of Debrecen
2019
Péterfy Sándor Utcai Kórház-Rendelőintézet és Baleseti Központ
2016-2017
Transgenic Arabidopsis thaliana plants overproducing the E2Fa-DPa transcription factor have two distinct cell-specific phenotypes: some cells divide ectopically and others are stimulated to endocycle. The decision of undergo extra mitotic divisions has been postulated depend on presence a mitosis-inducing (MIF). Plants possess unique class cyclin-dependent kinases (CDKs; B-type) for which no ortholog is found in other kingdoms. peak CDKB1;1 activity around G2-M boundary suggested that it...
Abstract The molecular mechanisms by which the phytohormone auxin coordinates cell division with growth and differentiation are largely unknown. Here, we show that in Arabidopsis thaliana E2FB, accumulation stability positively regulated auxin. Coexpression of but not E2FA, its dimerization partner A, stimulated proliferation absence tobacco (Nicotiana tabacum) Bright Yellow-2 cells. E2FB entry into both S- M-phases, latter corresponding to activation a plant-specific mitotic regulator,...
Abstract Multicellular organisms depend on cell production, fate specification, and correct patterning to shape their adult body. In plants, auxin plays a prominent role in the timely coordination of these different cellular processes. A well-studied example is lateral root initiation, which triggers founder specification cycle activation xylem pole–positioned pericycle cells. Here, we report that E2Fa transcription factor Arabidopsis thaliana an essential component regulates asymmetric...
Summary Plants sense pathogens through both pathogen‐associated molecular patterns and recognition of race‐specific virulence factors, which induce basal defence or an accelerated (often manifest in the form local cell death), respectively. A mitogen‐activated protein kinase (MAPK) module Arabidopsis was previously proposed to signal from perception bacterial elicitor flagellin activation defence‐related genes. Here, we present evidence for a parallel MAPK‐signalling pathway involved...
The eukaryotic cell division cycle is coordinated by cyclin-dependent kinases (CDKs), represented a single major serine/threonine kinase in yeasts (Cdc2/CDC28) and family of (CDK1 to CDK8) human cells. Previously, two cdc2 homologs, cdc2MsA cdc2MsB, have been identified alfalfa (Medicago sativa). By isolating cDNAs using probe, we demonstrate here that at least four additional homologous genes are expressed the tetraploid alfalfa. Proteins encoded new cdc2MsC cdc2MsF share characteristic...
The EL2 gene of rice (Oryza sativa), previously classified as early response against the potent biotic elicitor N-acetylchitoheptaose and encoding a short polypeptide with unknown function, was identified novel cell cycle regulatory related to recently reported SIAMESE (SIM) Arabidopsis thaliana. Iterative two-hybrid screens, in vitro pull-down assays, fluorescence resonance energy transfer analyses showed that Orysa; binds cyclin-dependent kinase (CDK) CDKA1;1 D-type cyclins. No interaction...
Abstract The rapidly proliferating cells in plant meristems must be protected from genome damage. Here, we show that the regulatory role of Arabidopsis RETINOBLASTOMA RELATED ( RBR ) cell proliferation can separated a novel function safeguarding integrity. Upon DNA damage, and its binding partner E2 FA are recruited to heterochromatic γH2 AX ‐labelled damage foci an ATM ‐ ATR ‐dependent manner. These lesions more dispersedly occupied by conserved repair protein, At BRCA 1, which also...
Abstract In darkness, shoot apex growth is repressed, but it becomes rapidly activated by light. We show that phytochromes and cryptochromes play largely redundant roles in this derepression Arabidopsis thaliana. examined the light activation of transcriptional changes a finely resolved time course, comparing (meristem leaf primordia) cotyledon found >5700 differentially expressed genes. Early events specific to apices included repression genes for Really Interesting New Gene finger...
The DNA of all organisms is constantly damaged by physiological processes and environmental conditions. Upon persistent damage, plant growth cell proliferation are reduced. Based on previous findings that RBR1, the only Arabidopsis homolog mammalian tumor suppressor gene retinoblastoma, plays a key role in damage response plants, we unravel here network RBR1 interactors under stress This led to identification homologs every DREAM component Arabidopsis, including previously not recognized...
How cell size and number are determined during organ development remains a fundamental question in biology. Here, we identified GRAS family transcription factor, called SCARECROW-LIKE28 (SCL28), with critical role determining Arabidopsis. SCL28 is part of transcriptional regulatory network downstream the central MYB3Rs that regulate G2 to M phase cycle transition. We show forms dimer AP2-type AtSMOS1, which defines specificity for promoter binding directly activates specific set...
In plant post-embryonic epidermis mitogen-activated protein kinase (MAPK) signaling promotes differentiation of pavement cells and inhibits initiation stomata. Stomata are specialized to modulate gas exchange water loss. Arabidopsis MAPKs MPK3 MPK6 at the core cascade; however, it is not well understood how activity these pleiotropic constrained spatially so that cell promoted only outside stomata lineage. Here we identified a PP2C-type phosphatase termed AP2C3 (Arabidopsis 2C) expressed...
Abstract Endoreduplication represents a variation on the cell cycle in which multiple rounds of DNA replication occur without subsequent chromosome separation and cytokinesis, thereby increasing cellular content. It is known that ploidy level cells controlled by external stimuli such as light; however, limited knowledge available how environmental signals regulate endoreduplication at molecular level. Previously, we had demonstrated conversion from mitotic into an atypical E2F transcription...
Plants respond to higher ambient temperatures by modifying their growth rate and habitus. This review aims summarize the accumulated knowledge obtained with Arabidopsis seedlings grown at normal elevated temperatures. Thermomorphogenesis in shoot root is overviewed separately, since experiments indicate differences key aspects of thermomorphogenesis two organs. includes variances thermosensors transcription factors, as well predominance cell elongation or division, respectively, even though...
E2F/DP complexes play a pivotal role in the regulation of G1/S transition animals. Recently, plant E2F homologs have been cloned, but DP‐related sequences not identified so far. Here we report that Arabidopsis thaliana contains at least two different genes, AtDPa and AtDPb . They exhibit an overall domain organization similar to their animal counterparts, although phylogenetic analysis demonstrated they form separate subgroup. AtDPs efficiently heterodimerize vitro with E2F‐related proteins,...