A5074841220- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Substance Abuse Treatment and Outcomes
- Neurotransmitter Receptor Influence on Behavior
- Alcohol Consumption and Health Effects
- Genetic Associations and Epidemiology
- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Receptor Mechanisms and Signaling
- Child and Adolescent Psychosocial and Emotional Development
- Attention Deficit Hyperactivity Disorder
- Prenatal Substance Exposure Effects
- Suicide and Self-Harm Studies
- Heart Rate Variability and Autonomic Control
- Biochemical Analysis and Sensing Techniques
- Advanced Neuroimaging Techniques and Applications
- Mental Health Research Topics
- Neuroscience and Music Perception
- Cardiac electrophysiology and arrhythmias
- Child Abuse and Trauma
- Stress Responses and Cortisol
- Smoking Behavior and Cessation
- Cognitive Abilities and Testing
SUNY Downstate Health Sciences University
2016-2025
State University of New York
2010-2024
Washington University in St. Louis
1998-2009
Indiana University – Purdue University Indianapolis
1998-2009
UConn Health
1998-2009
University of California, San Diego
2009
University of Iowa Hospitals and Clinics
2009
RELX Group (United States)
2006
Texas Biomedical Research Institute
1998-2002
University of Iowa
1998-2002
Introduction: Research has identified multiple risk factors associated with suicide attempt (SA) among individuals psychiatric illness. However, there is limited research those an alcohol use disorder (AUD), despite their disproportionately higher rates of SA. Methods: We examined lifetime SA in 4,068 AUD from the Collaborative Study on Genetics Alcoholism (23% SA; 53% female; mean age: 38). explored for across other clinical conditions ascertained a interview, polygenic scores comorbid...
Human brain oscillations represent important features of information processing and are highly heritable. A common feature beta (13–28 Hz) is the critical involvement networks inhibitory interneurons as pacemakers, gated by γ-aminobutyric acid type (GABA ) action. Advances in molecular statistical genetics permit examination quantitative traits such frequency human electroencephalogram conjunction with DNA markers. We report a significant linkage disequilibrium between set GABA receptor...
Objective: Impulsivity is an important characteristic of many psychiatric disorders, including substance‐related disorders. These disinhibitory disorders have a similar underlying genetic diathesis, with each disorder representing different expression the same liability. This study assessed whether there relationship between impulsivity and alcohol dependence, their correlations P3 (P300) amplitude, proposed endophenotype alcoholism. Methods: Healthy control subjects ( n =58) DSM‐IV...
Abstract Oscillatory activity is crucial for information processing in the brain, and has a long history as biomarker psychopathology. Variation oscillatory highly heritable, but current understanding of specific genetic influences remains limited. We performed largest genome‐wide association study to date power during eyes‐closed resting electroencephalogram (EEG) across range frequencies (delta 1–3.75 Hz, theta 4–7.75 alpha 8–12.75 beta 13–30 Hz) 8,425 subjects. Additionally, we KGG...
Recent data collected at six identical electrophysiological laboratories from the large national multisite Collaborative Study on Genetics of Alcoholism provide evidence for considering P3 amplitude event‐related potential as a phenotypic marker risk alcoholism. The distribution to target stimuli Pz electrode in individuals 16 years age and over 163 randomly ascertained control families ( n = 687) was compared with those 219 densely affected alcoholic 1276) which three directly interviewed...
Event-related oscillations (EROs) represent highly heritable neuroelectric correlates of cognitive processes that manifest deficits in alcoholics and offspring at high risk to develop alcoholism. Theta ERO targets the visual oddball task has been shown be an endophenotype for A family-based genome-wide association study was performed frontal theta phenotype using 634 583 autosomal single nucleotide polymorphisms (SNPs) genotyped 1560 family members from 117 families densely affected by...
Abstract Predictive models for recovering from alcohol use disorder (AUD) and identifying related predisposition biomarkers can have a tremendous impact on addiction treatment outcomes cost reduction. Our sample ( N = 1376) included individuals of European (EA) African (AA) ancestry the Collaborative Study Genetics Alcoholism (COGA) who were initially assessed as having AUD (DSM-5) reassessed years later either or in remission. To predict this difference recovery status, we analyzed initial...