Donghui Li

ORCID: 0000-0001-8466-8697
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About
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Research Areas
  • Viral Infections and Immunology Research
  • Traditional Chinese Medicine Analysis
  • Complex Network Analysis Techniques
  • Transplantation: Methods and Outcomes
  • Traditional Chinese Medicine Studies
  • Vacuum and Plasma Arcs
  • Ocular Surface and Contact Lens
  • Pharmacological Effects of Natural Compounds
  • Web Data Mining and Analysis
  • Pickering emulsions and particle stabilization
  • Proteins in Food Systems
  • Ophthalmology and Eye Disorders
  • Electrical Fault Detection and Protection
  • Food Chemistry and Fat Analysis
  • Advanced Drug Delivery Systems
  • Flavonoids in Medical Research
  • Medicinal Plant Pharmacodynamics Research
  • Wastewater Treatment and Nitrogen Removal
  • Tissue Engineering and Regenerative Medicine
  • Electrical Contact Performance and Analysis
  • Spam and Phishing Detection
  • Inflammasome and immune disorders
  • Atmospheric Ozone and Climate
  • Freezing and Crystallization Processes
  • Computational Drug Discovery Methods

Shandong Provincial Hospital
2025

Shandong First Medical University
2025

Huazhong Agricultural University
2023-2024

Harbin Institute of Technology
2021-2023

Harbin Engineering University
2023

Gansu University of Traditional Chinese Medicine
2021-2022

Sorrento Therapeutics (United States)
2022

Jimei University
2022

Harbin University of Science and Technology
2021

Xiamen University
2017

The natural product berberine (BBR), present in various plants, arouses great interests because of its numerous pharmacological effects. However, the further development and application BBR had been hampered by poor oral bioavailability. In this work, we report on polymer–lipid hybrid nanoparticles (PEG–lipid–PLGA NPs) loaded with phospholipid complex using a solvent evaporation method for enhancing efficiency. advantage new drug delivery system is that BBR–soybean phosphatidylcholine...

10.1080/10717544.2017.1321062 article EN cc-by-nc Drug Delivery 2017-01-01

Black carbon (BC), brown (BrC), and mineral dust (DU) are three major light absorbing aerosols, playing important roles in climate change. Better knowledge of their concentrations is necessary for more accurate estimates radiative forcing effects climate. We present a method to retrieve columnar contents BC, BrC, DU simultaneously from spectral refractive indices single scattering albedo obtained the sun‐sky radiometer measurements. Then, this applied investigate volume fractions mass...

10.1002/jgrd.50356 article EN Journal of Geophysical Research Atmospheres 2013-04-23

Atherosclerosis and aortic aneurysms are prevalent cardiovascular diseases in the elderly, characterized by chronic inflammation oxidative stress. This study explores role of CircXYLT1 regulating stress vascular remodeling age-related diseases. RNA sequencing revealed a significant upregulation tissues aged mice, highlighting its potential Using carotid artery wire injury model, we performed adeno-associated virus (AAV)-mediated knockdown overexpression CircXYLT1. Key markers, including...

10.1016/j.exger.2025.112690 article EN cc-by-nc-nd Experimental Gerontology 2025-02-07

The numerous health benefits of olive oil are widely known, however, it also provides anti-allergic properties that have not yet been fully defined. In this study, the activity was evaluated by analyzing clinical symptoms and immune-related factors in BALB/c mice had ingested 600 mg/(kg∙day) for two weeks prior to evaluation. An allergy model subsequently constructed analysis, results which showed reduced scores allergic mice, up-regulated hypothermia decline immune organ index. Moreover,...

10.1016/j.fshw.2022.09.015 article EN cc-by-nc-nd Food Science and Human Wellness 2022-10-15

Hedysari Radix Praeparata Cum Melle (HRPCM) and Astragali (ARPCM) are used interchangeably in clinics to treat spleen-qi deficiency (SQD) symptom mainly including gastrointestinal dysfunction decreased immunity, which has unknown differences efficacy.To investigate the between HRPCM ARPCM on intervening gastrointestinal- immune-function with SQD syndrome.After model was established, Sprague-Dawley (SD) rats were randomly divided into nine groups (n = 10): normal; model; Bu-Zhong-Yi-Qi Pills;...

10.1080/13880209.2022.2086990 article EN cc-by Pharmaceutical Biology 2022-06-28

ABSTRACT The continual emergence of SARS-CoV-2 variants concern, in particular the newly emerged Omicron (B.1.1.529) variant, has rendered ineffective a number previously EUA approved neutralizing antibody therapies. Furthermore, even those antibodies with activity against are reportedly subset that contain R346K substitution, demonstrating continued need for discovery and characterization candidate therapeutic breadth potency required to treat diagnosed COVID-19 linked recently concern....

10.1101/2022.01.19.476998 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-01-20

Sina Weibo, as one of the most popular and fast growing social network, has gradually become field where hot topics appear, propagate, outbreak.In order to discriminate find out in micro-blog information, we conduct a series studies on our key findings is that opinion leaders play very important role propagation topics.A smart discriminant model proposed this paper detect time, which takes structure information characteristics Weibo well users' influence into consideration.Moreover, word...

10.2991/ccit-14.2014.47 article EN cc-by-nc 2014-01-01

Abstract Produced water is the main by-product of oilfield extraction process. Due to its high emulsification degree and density close water, micron oil droplets are inefficiently separated by ordinary cyclone, it difficult meet standards external discharge reinjection after treatment. In this study, bubbles were prepared mixing hydrocarbon components as gas passed into cyclone separator enhance oil-water separation effect. After entered due pressure environment inside, heavier in found...

10.1088/1742-6596/2834/1/012102 article EN Journal of Physics Conference Series 2024-10-01

Early classification and diagnosis of lung diseases is essential to increase the best chance patient recovery survival. Using deep learning make it possible, key how improve robustness model accuracy image classification. In order classify five diseases, we used transfer fine-tune fully connected layer VGG16, cross entropy loss function, combined with gradient boosting decision tree (GBDT), establish a called classifier. The was trained using ChestX-ray14 dataset. On test set, our for...

10.1142/s0219519421500421 article EN Journal of Mechanics in Medicine and Biology 2021-05-01

This Radix study cum aims Melle to explore(HRPM)the on efficacy spleen differences deficiency between syndrome.modeling Astragali A of Praeparata110cum rats were(ARPM)randomized fatigue),and into Hedysari a Praeparata(n qi total irregular HRPM male diet,SD diarrhea,control were(n Yiqi=10)the=100).Pill group fied and model modeling group,group Buzhong After(BYP)(through ARPM the HRPM-H),classimedium-dose into(ARPM-M raised group,and high-dose(ARPM-H each Rats BYP under HRPM-M),normal low-dose...

10.19540/j.cnki.cjcmm.20210310.301 article EN PubMed 2021-11-01

The first micro-blog service appeared in China was Sina Weibo, it has developed very fast recent years. Some hot topics have a significant impact on the public opinion formation and dissemination. Also, potential security risks are absolutely not being underestimated. In order to extract topics, this paper proposes an algorithm called CBOS (Clustering Based Sentence) compares with classic K-means so on. results show that is different, offers new perspective people topics. And research...

10.1109/uic-atc-scalcom-cbdcom-iop.2015.128 article EN 2015-08-01

To investigate the effect of bone marrow mesenchymal stem cells (BMSCs) on ureteral injury repair via renal artery transplantation.The left obstruction model was set up in 49 Balb/c mice by micro vascular clamp. The microscopic clamp taken out to lift after 10 days. were randomly divided into an experimental group (n=25) and a control (n=24). BMSCs transfected luciferase (Luc) transplanted immediately through removing from group; while closed incision removed without transplant. Magnetic...

10.11817/j.issn.1672-7347.2014.03.010 article EN PubMed 2014-03-01

Probability of arc re-strike increases with the increment break voltage, especially in an chamber DC bridge-type contacts equipped permanent magnets. Among all types re-strikes, most dangerous one is that part re-enters contact gap, which defined as swirl this paper. In paper, images and voltage waveforms were analyzed, typical features identified. addition, probability when supply voltages range from 270 V to 730 magnetic flux densities ranges 30 mT 70 revealed. Mechanism explained it due...

10.1109/access.2023.3341511 article EN cc-by-nc-nd IEEE Access 2023-01-01
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