A5006894730- Escherichia coli research studies
- Vector-borne infectious diseases
- Insect and Pesticide Research
- Venomous Animal Envenomation and Studies
- Insect Resistance and Genetics
- Insect Pest Control Strategies
- Vector-Borne Animal Diseases
- Enterobacteriaceae and Cronobacter Research
- Aquaculture Nutrition and Growth
- Bacteriophages and microbial interactions
- Marine Invertebrate Physiology and Ecology
- Aquaculture disease management and microbiota
- Drug Transport and Resistance Mechanisms
- T-cell and Retrovirus Studies
- Antibiotic Resistance in Bacteria
- Toxin Mechanisms and Immunotoxins
- Enzyme Production and Characterization
- Entomological Studies and Ecology
- Helminth infection and control
- Ion channel regulation and function
- Protein Hydrolysis and Bioactive Peptides
- Mycobacterium research and diagnosis
- Pharmacological Effects and Toxicity Studies
- Reproductive biology and impacts on aquatic species
- Inflammasome and immune disorders
Instituto Butantan
2023-2025
Universidade Federal do Rio Grande do Sul
2005-2018
Universidade de São Paulo
2014-2017
Universität Innsbruck
1998
Centre Hospitalier Universitaire de Saint-Pierre
1986
In ticks, the digestion of blood occurs intracellularly and proteolytic hemoglobin takes place in a dedicated type lysosome, digest vesicle, followed by transfer heme moiety to specialized organelle that accumulates large aggregates, called hemosomes. present work, we studied uptake fluorescent metalloporphyrins, used as analogs, amitraz, one most regularly acaricides control cattle tick infestations, Rhipicephalus (Boophilus) microplus midgut cells. Both compounds were taken up cells vitro...
The tick Rhipicephalus (Boophilus) microplus (formerly Boophilus microplus) is the major ectoparasite affecting livestock in America, Asia, Africa, and Oceania.Conventional control based on use of acaricides but immunization bovines with gut proteins induces only a partial protective immune response.Based this information, distinct research groups have explored possibility protecting animals by inducing an response against other proteins.However, antigens so far described do not induce...
Background The caterpillar of Premolis semirufa , known as Pararama, is found in the Brazilian Amazon, primarily on rubber trees genus Hevea . Pararamosis an inflammatory disease resulting from accidental contact with caterpillar’s bristles, leading to acute and chronic symptoms. Chronic exposure can cause significant osteoarticular deformities, similar those seen osteoarthritis rheumatoid arthritis, due cartilage degradation synovial inflammation. Currently, there are no specific treatments...
Dermonecrosis resulting from Loxosceles spider envenomation, primarily driven by the enzyme sphingomyelinase D (SMase D), is characterized severe inflammation and nonhealing wounds. SMases can be classified as Class I or II based on their structural characteristics. exhibits greater dermonecrotic activity than II; however, intracellular mechanisms responsible for this difference remain poorly understood. The differential transcriptomics analysis of human keratinocytes treated with each toxin...
Boophilus microplus é um ectoparasita hematófago de bovinos, presente em áreas tropicais e subtropicais no mundo. É causador enormes perdas econômicas pela espoliação que causa ao hospedeiro, além ser transmissor Anaplasma sp. Babesia spp. O principal método controle utilizado atualmente o químico, que, embora eficiente, caro, danos meio ambiente deixa resíduos na carne. Além disso, crescente número relatos apontam aumento das populações resistentes carrapatos a diversos princípios químicos...
The cattle tick Rhipicephalus microplus is one of the most economically damaging livestock ectoparasites, and its widespread resistance to acaricides a considerable challenge control. In this scenario, establishment resistant cell lines useful approach understand mechanisms involved in development acaricide resistance, identify drug markers, develop new acaricides. This study describes an ivermectin (IVM)-resistant R. embryonic line, BME26-IVM. cells were obtained after exposure...
It is well known that reactive oxygen species (ROS) and nitrogen (RNS) are involved in the control of pathogens microbiota insects. However, knowledge role ROS RNS tick-pathogen tick-microbiota interactions limited. Here, we evaluated immune-related redox metabolism embryonic cell line BME26 from cattle tick Rhipicephalus microplus response to Anaplasma marginale infection. A high-throughput qPCR approach was used determine expression profile 16 genes encoding proteins either production or...
The cattle tick Rhipicephalus microplus is widely distributed in tropical and subtropical regions, causing high economic impact on production. control of infestations regarded worldwide as critical has been based the use organophosphates, synthetic pyretroids, amitraz recently ivermectin fipronil. present study reports analysis by gas chromatography/mass spectrometry constituents leaf extracts Croton sphaerogynus results acaricidal activity against R. microplus. larval package test using...
Pararamosis, also known as Pararama-associated phalangeal periarthritis, is a neglected tropical disease primarily affecting rubber tappers in the Amazon region. It caused by contact with urticating hairs of