A5100655262- Epigenetics and DNA Methylation
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Histone Deacetylase Inhibitors Research
- Educational Reforms and Innovations
- Plant-Microbe Interactions and Immunity
- Ferroelectric and Piezoelectric Materials
- Medical Research and Treatments
- Mycorrhizal Fungi and Plant Interactions
- Noise Effects and Management
- Autophagy in Disease and Therapy
- Ubiquitin and proteasome pathways
- PI3K/AKT/mTOR signaling in cancer
- Plant Pathogens and Fungal Diseases
- Nanoplatforms for cancer theranostics
- vaccines and immunoinformatics approaches
- Environmental Quality and Pollution
- Environmental DNA in Biodiversity Studies
- Inflammasome and immune disorders
- Geoscience and Mining Technology
- CRISPR and Genetic Engineering
- Growth Hormone and Insulin-like Growth Factors
- Bamboo properties and applications
- Magnesium Oxide Properties and Applications
- Face recognition and analysis
Northwest University
2019-2025
Yibin University
2023-2025
Chongqing Three Gorges University
2024
University of Science and Technology of China
2024
Xi'an Medical University
2024
Zhejiang University
2024
Third Affiliated Hospital of Guangzhou Medical University
2024
Guangzhou Medical University
2024
Hangzhou Medical College
2023
Zhejiang Provincial People's Hospital
2023
Breast cancer (BC) subtypes exhibit distinct epigenetic landscapes, with triple-negative breast (TNBC) lacking effective targeted therapies. This study investigates histone biomarkers and therapeutic vulnerabilities across BC subtypes. The immunohistochemical profiling of >20 biomarkers, including modifications, modifiers, oncohistone mutations, was conducted on a discovery cohort validation tissues, healthy controls, cell line models. Transcriptomic growth analyses were to evaluate the...
Bamboo is a sustainable and degradable resource for sustenance, high-strength cellulose microfibers, synthetic fiber in China. Endophytic bacteria enhance root development ethylene levels, benefiting the host plants' physiology. We investigated population, diversity, abundance of endophytic leaves three bamboo species-Phyllostachys edulis, Bambusa rigida, Pleioblastus amarus-using high-throughput 16S rDNA sequencing. A total 1,159 operational taxonomic units (OTUs) were obtained further...
Osteoporosis (OP) is the result of bone mass reduction and structure disorder. Bone marrow mesenchymal stem cells (BMSCs) are main source osteogenic precursor involved in adult remodeling. The involvement deubiquitinating enzyme CYLD OP has recently been discovered. However, detailed role mechanism remain unknown.
Abstract: All-solid-state thin film lithium batteries (TFBs) are regarded as the ideal power source for microelectronics in upcoming era of Internet Things, owing to their solid-state architecture, flexible size and shape, long cycle life, low self-discharge rate, facile miniaturization. Even though tremendous improvements have been made TFBs last decades, recycling TFBs, which is supposed be a serious issue future, rarely studied. With continuous TFB market expansion, sustainable...
Combining a tetra-primer ARMS-PCR with LFA for simultaneous visual detection of both alleles.
Abstract In this paper, we theoretically and experimentally reported a lead‐free pyroelectric infrared (PIR) detector using (Bi 1/2 Na TiO 3 )‐BaTiO (BNT‐BT) ferroelectric ceramics as the sensitive material. The variation of noise density, voltage response rate ( R V ), specific detection D *) with modulation frequency under current mode amplification circuit was investigated, it found that PIR showed high in low band. * reached 1.51 × 10 5 V/W 2.02 8 cmHz W −1 at Hz, respectively. results...
Presently, clopidogrel is the standard therapeutic drugs for antiplatelet therapy. Variants in CYP2C19 gene influence clinical response of clopidogrel. Thus, US Food and Drug Administration suggested genotyping needs to identify before taking medicine. Due high cost, time consuming, sophisticated instruments, current single nucleotide polymorphism detection methods are limited application. In present study, we established a method CYP2C19, which combines amplification refractory mutation...
This study aimed to observe the effects of puerarin on glycolysis and cisplatin sensitivity in oral squamous cell carcinoma (oSCC) cells explore underlying mechanisms. CAL27 over- or under-expressing FBXW7 were treated with puerarin, levels proteins involved as well activity respective enzymes assessed. Glucose uptake lactate production also evaluated, IC50 value was determined. overexpression significantly downregulated HK2, PKM2, LDH; suppressed corresponding hexokinase, pyruvate kinase,...
Aucuba japonica Thunb is an evergreen woody ornamental plant with significant economic and ecological values. It also produces aucubin, showing a variety of biological activities. widely planted in the southwest region China, including karst landscape areas Guizhou Province. In January 2022, serious leaf blight disease was observed on leaves A. outdoor gardens University, Guiyang, Guizhou, China. The causal agent identified as Colletotrichum aenigma through amplification sequencing internal...
Fungal endophytes in plant leaf mesophyll form mutually beneficial associations through carbon assimilation, synthesis of biologically active chemicals, and enhancement aesthetic nutritional value. Here, we compared community structure, diversity, richness endophytic fungi the leaves three bamboo species, including Phyllostachys edulis (MZ), Bambusa rigida (KZ), Pleioblastus amarus (YT) via high-throughput Illumina sequencing. In total, 1070 operational taxonomic units (OTUs) were retrieved...
Insertions/deletions (indels) variations have been recognized as a promising marker for the development of various diseases. However, methods used genotyping indels in studies were tedious, complicated, and required sophisticated or expensive instruments, well complex data analysis, which makes it difficult to meet demand point care testing. Herein, we presented fast accurate biosensor (T-ARMS-PCR-LFA) by combination tetra-primer amplification refractory mutation system polymerase chain...
Abstract In order to improve the construction technology level of connection nodes prefabricated buildings and mechanical properties, fluidity economy mortar, this paper adopts orthogonal experimental design cement mortar by adding polymer dispersible powder. A modified high-performance with 1d compressive strength 11Mpa, 3d 19Mpa, 7d 26Mpa, 102 mm final higher than M25 was studied. The factors levels test are: ratio 1:3,1:4,1:5; silica powder content 4%,6%,8%; 3%,5%,7%. After research,...
Optical and magnetic signals facilitate the result interpretation 0.1% target variant can be distinguished within 90 min from sequence discrepancy.