Chiara Franceschini

ORCID: 0000-0001-8683-1320
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Research Areas
  • Cutaneous lymphoproliferative disorders research
  • Cutaneous Melanoma Detection and Management
  • Dermatology and Skin Diseases
  • Hidradenitis Suppurativa and Treatments
  • Nonmelanoma Skin Cancer Studies
  • Colorectal and Anal Carcinomas
  • Hair Growth and Disorders
  • Cancer and Skin Lesions
  • Fungal Infections and Studies
  • Skin and Cellular Biology Research
  • Dermatologic Treatments and Research
  • Oral Health Pathology and Treatment
  • Chemotherapy-related skin toxicity
  • Dermatological and Skeletal Disorders
  • Nail Diseases and Treatments
  • Autoimmune Bullous Skin Diseases
  • Skin Protection and Aging
  • Contact Dermatitis and Allergies
  • Genetic and rare skin diseases.
  • Optical Coherence Tomography Applications
  • Pathogenesis and Treatment of Hiccups
  • Tumors and Oncological Cases
  • Urticaria and Related Conditions
  • Hepatitis C virus research
  • Dupuytren's Contracture and Treatments

San Gallicano Hospital
2018-2024

Istituti di Ricovero e Cura a Carattere Scientifico
2018-2024

University of Rome Tor Vergata
2013-2022

Policlinico Tor Vergata
2019

<b><i>Background:</i></b> Plaque psoriasis (PP) and seborrheic dermatitis (SD) are chronic inflammatory skin diseases with similar clinical pathological features. Differential diagnosis can be difficult, especially when particular areas of the face involved. Reflectance confocal microscopy (RCM) has been demonstrated to useful for ‘real-time' diseases. <b><i>Objective:</i></b> To define distinctive criteria SD evaluate usefulness this technique...

10.1159/000363289 article EN Dermatology 2014-01-01

<b><i>Background/Aims:</i></b> The association between hidradenitis suppurativa (HS) and multiple comorbidities has been widely investigated but data about the coexistence of Down syndrome (DS) are scarce. We sought to evaluate prevalence DS among a population HS patients assess their clinical features. <b><i>Methods:</i></b> collected demographic affected with referred three Italian outpatient dermatology clinics....

10.1159/000487799 article EN Dermatology 2018-01-01

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that impairs patients' quality of life. Various psychiatric or psychological conditions have been associated with HS, however, no data are available on alexithymia, construct characterized by the inability to express, describe, and recognize feelings. To assess presence alexithymia in HS patients. Demographic clinical from patients were collected. Alexithymia was assessed using Toronto Scale (TAS)-20 questionnaire define...

10.1684/ejd.2018.3368 article EN European Journal of Dermatology 2018-07-01

Reflectance confocal microscopy (RCM) is a high-resolution, noninvasive imaging technique being increasingly used as an aid to diagnosis in the dermatology setting. RCM applied of both melanoma and nonmelanoma skin tumors, but also interpretation management inflammatory diseases. Two different devices with designs for specific indications are available market: static handheld probe. Several clinical presentations lesion could affect examination, such presence ulceration or hyperkeratosis;...

10.5826/dpc.1002a32 article EN cc-by-nc Dermatology Practical & Conceptual 2020-04-03

Background: Actinic keratosis (AK) is considered an "in situ" non-melanoma skin cancer induced by ultraviolet chronic exposure. Sunscreen and topical anti-inflammatory agents like diclofenac could improve the evolution of this kind lesions. A product containing piroxicam 0.8% sun filters (50 SPF) (ACTX) has been shown to be very effective in reducing AK So far, no data are available regarding effects on modifications evaluated reflectance confocal microscopy (RCM) dermoscopy at lesion sites...

10.1080/03007995.2019.1626227 article EN Current Medical Research and Opinion 2019-05-31

Actinic keratosis is an intraepithelial proliferation of atypical keratinocytes that could progress into invasive squamous cell carcinoma. Most evidence suggests important role the dermal matrix metalloproteinases in progression skin epithelial lesions. We evaluated clinical efficacy three different therapeutic modalities (a medical device containing 0.8% piroxicam cream and 50+ sunscreen, photodynamic therapy, ingenol mebutate gel) to treat suspicious actinic keratoses, which were biopsied...

10.3390/ijms231911351 article EN International Journal of Molecular Sciences 2022-09-26

Xerosis and atopic dermatitis (AD) are chronic skin conditions that occur in children adults which can result scaling, flaking itching. Risk factors for xerosis include sunlight, friction, low humidity use of soaps. is also a symptom cutaneous such as psoriasis, ichthyosis. AD has complex pathogenesis but there increased evidence genetically-impaired barrier plays primary role its development.The aim this study to evaluate the efficacy combination product topical application be used daily...

10.23736/s0392-0488.18.06002-9 article EN Giornale Italiano di Dermatologia e Venereologia 2019-01-01

Chemotherapy-induced alopecia (CIA) affects 65% of patients receiving chemotherapy regimens and is often identified with the massive hair loss stage. Reflectance confocal microscopy (RCM) a noninvasive technique used in assessment for disease characterization state activity.To describe RCM features CIA different timing identify specific phases development.A total 16 treated underwent dermoscopy evaluations four times during observation: 2 4-6 weeks after starting 3 6 months end chemotherapy....

10.1111/srt.12790 article EN Skin Research and Technology 2019-09-26

The differential diagnosis between regressing nevi and melanoma might be challenging; areas can represent a confounding factor for the histology still remain mandatory to rule out melanoma. Reflectance confocal microscopy may add valuable information by revealing features suggestive of nature melanocytic proliferation.To assess impact in management regressive lesions.The dermoscopic analysis 92 lesions showing that more than 30% regressions have been retrospectively considered, among them,...

10.1111/srt.12382 article EN Skin Research and Technology 2017-05-21

Citation: Persechino F, Giordano D, Marini CD, Franceschini C, ArdigM, S. Dermoscopy, optical coherence tomography, and histological correlation of pseudoxanthoma elasticum. Dermatol Pract Concept. 2019;9(3):209-210. DOI: https://doi.org/10.5826/dpc.0903a07

10.5826/dpc.0903a07 article EN cc-by-nc Dermatology Practical & Conceptual 2019-07-31

Abstract Introduction Small‐sized pigmented lesions (SSPL) <3 mm in diameter are common pitfall the daily dermatology practice. Dermoscopy alone is hampered by lack of specific features inversely proportional to and its performance highly operator‐dependent. Reflectance confocal microscopy (RCM) has been demonstrated be effective diagnosis several difficult where dermoscopy lacks provide conclusive information. Materials Methods A total 179 with uncertain or equivocal clinical appearance...

10.1111/srt.12863 article EN Skin Research and Technology 2020-03-24

BACKGROUND: Enlarging melanocytic lesions with peripheral globular pattern (EMLPGP) are a pitfall in dermoscopy. Our aim was to evaluate the meaning of EMLPGP and assess use dermoscopy reflectance confocal microscopy (RCM) order improve clinical management this subtype lesions.METHODS: A total 135 were recruited and, accordingly features, removed; later, an expert dermoscopist reviewed blinded histology. Moreover, subgroup 63 who underwent also RCM, by confocalist.RESULTS: Patients had...

10.23736/s2784-8671.19.06471-x article EN Italian Journal of Dermatology and Venereology 2021-10-01

BACKGROUND Enlarging melanocytic lesions with peripheral globular pattern (EMLPGP) are a pitfall in dermoscopy. Our aim was to evaluate the meaning of EMLPGP and assess use dermoscopy reflectance confocal microscopy (RCM) order improve clinical management this subtype lesions. METHODS A total 135 were recruited and, accordingly features, removed; later, an expert dermoscopist reviewed blinded histology. Moreover, subgroup 63 who underwent also RCM, by confocalist. RESULTS Patients had median...

10.23736/s0392-0488.19.06471-x article EN Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia 2021-08-01

Pseudoxanthoma elasticum (PXE) is a rare genetic autosomal recessive metabolic disease characterized by progressive mineralization and fragmentation of elastic fibers from soft connective tissues. The objective our study was to analyze the epidemiological, genetic, cutaneous, extracutaneous clinical data largest Italian monocentric cohort PXE patients.

10.23736/s2784-8671.24.07949-0 article EN Italian Journal of Dermatology and Venereology 2024-07-01
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