Zinc (Zn) alloy porous scaffolds produced by additive manufacturing own customizable structures and biodegradable functions, having a great application potential for repairing bone defect. In this work, hydroxyapatite (HA)/polydopamine (PDA) composite coating was constructed on the surface of Zn-1Mg fabricated laser powder bed fusion, loaded with bioactive factor BMP2 an antibacterial drug vancomycin. The microstructure, degradation behavior, biocompatibility, performance osteogenic...

Abstract Objectives A patient with extensive atrophy of the alveolar ridge in posterior portion maxilla was selected to complete an experimental and clinical case robotic zygomatic implant investigate viability system use. Methods The preoperative digital information collected, implantation position personalized optimization marks needed for robot surgery were designed advance a repair-oriented way. resin models patient’s mandible are all printed 3D. Custom-made special precision drills...

Abstract The combination of bioactive Zn‐2Mg alloy and additively manufactured porous scaffold is expected to achieve customizable biodegradable performance enhanced bone regeneration. Herein, scaffolds with different porosities, including 40% (G‐40‐2), 60% (G‐60‐2), 80% (G‐80‐2), unit sizes, 1.5 mm (G‐60‐1.5), 2 2.5 (G‐60‐2.5), are by a triply periodic minimal surface design reliable laser powder bed fusion process. With the same size, compressive strength (CS) elastic modulus (EM)...

The aim of the study was to test feasibility using commercially available computer-aided design and manufacturing (CAD/CAM) technology including 3Shape Dental System 2013 trial version, WIELAND V2.0.049 ZENOTEC T1 milling machine fabricate complete dentures. modeling process full denture in version used virtual dentures on basis 3-dimensional (3D) digital edentulous models generated from physical models. designed were exported CAM software V2.0.049. A controlled by dentitions baseplates...

Abstract Segmentation of a complete set teeth from three-dimensional (3D) intra-oral scanner images is crucial step in tooth identification procedures. In large-scale disasters with many victims, are often the preferred and reliable source for victim due to their hard non-deformable characteristics. this paper we present study on automatic segmentation images. We propose method based an improved PointNet++ architecture. To address problem inadequate capability teeth-gingival boundary...

Aims It has been reported that cardiac ankyrin repeat protein is associated with heart development and diseases. This study aimed to investigate the role of CARP in hypertrophy vivo. Methods Results We generated a cardiac-specific CARP-overexpressing transgenic mouse. Although such animals did not display any overt physiological abnormality, they developed less response pressure overload than wildtype mice, as indicated by weight/body weight ratios, echocardiographic histological analyses,...

Abstract Background In the current study, we aimed to evaluate accuracy of indirect bonding by either three-dimensional (3D) printing guides or double-layer guide plates. The results may serve as a clinical reference for bracket placements. Methods total, 140 teeth were collected and arranged into five pairs full dentition. marking points labeled on buccal/labial surface crown in these orthodontic study models. (1) 3D : A digital profile was generated using an intraoral scanner. Two types...

Soil frost heave acts as a driver of the emerged fracture in concrete lining irrigation canals and subsequent water leakage seasonal frozen ground. A model test was carried out on U‐shaped canal with lining. The heat migration during freezing, heave‐induced deformation, force normal direction were live monitored by high‐precision transducers. results prove that freezing front descends downward over time at specified thermal boundary, considerable within scope 0–40 cm. maximum deformation...

Aggregation and neurotoxicity of the presynaptic protein α-synuclein progressive loss nigral dopaminergic neurons are believed to be key hallmarks Parkinson's disease (PD). A53T mutant causes early onset PD more severe manifestations. A growing body evidence shows that misfolding or deposition is linked maintenance mitochondrial dynamics, which has been proven play an important role in pathogenesis PD. It observed Dl-3-n-butylphthalide (NBP) may safe effective improving non-tremor-dominant...

Abstract How to ensure dental stability in new positions and reduce the likelihood of relapse is a major clinical concern orthodontic field. Occlusal contacts between arches may affect transmission masticatory forces, thereby influencing biological response periodontal oromandibular system. Occlusion factors that influence after tooth movement (OTM) remain largely unknown. Hence, this research was conducted order investigate different occlusal contact patterns on system including masseter...

Coalbed methane (CBM), recognized as a sustainable and environmentally friendly energy source, plays crucial role in mitigating global climate change advancing low-carbon solutions. However, the prevalence of low-permeability coal seams poses significant challenge to effective CBM extraction. Improving permeability has emerged viable strategy address issue coal. Conventional stimulation methods fall short overcoming this obstacle. In contrast, enhanced technique extraction by water-based...

The aim of the study is to evaluate effect modifying collagen matrices with Arg-Gly-Asp (RGD) peptide through periodate oxidation. were modified RGD peptide, by activation. and unmodified characterized scanning electron microscopy (SEM), differential calorimetry (DSC), spectroscopy for chemical analysis (ESCA). Mesenchymal stem cells (MSCs) used cell compatibility matrices. In terms growth, MSCs attached much better on matrix than one. But there was no significant difference between two...

The demand for complete dentures is expected to increase worldwide, but are mainly designed and fabricated manually involving a broad series of clinical laboratory procedures. Therefore, the quality largely depends on skills dentist technician, leading difficulty in control. Computer-aided design manufacturing (CAD/CAM) has been used fabricate various dental restorations including inlays, veneers, crowns, partial fixed (FPDs). It envisioned that application CAD/CAM technology could reduce...

Intraoral scans (IOS) provide precise 3D data of dental crowns and gingival structures. This paper explores an application IOS in human identification.

Anti-vascular endothelial growth factor (VEGF) has been used as a therapeutic drug for the treatment of some human diseases. However, no systematic evidence is performed assessing role VEGF in periodontitis. We carried out comprehensive analysis to explore patients with

Background: This study attempts to detect the potential effects of local bone morphogenetic protein -2 (BMP-2) on orthodontic tooth movement and periodontal tissue remodeling. Methods: Forty adult SD rats were randomly divided into four groups: blank control group, unilateral injection BMP-2 pressure side or tension teeth bilateral BMP-2. Their maxillary first molar was moved by a 30 g constant force closed coil spring. 60 μL with concentration 0.5 μg/mL injected each part at time. In...

Abstract The human permanent dentition has been commonly used for personal identification due to its uniqueness. Limited research, however, is conducted using 3D digital dental models. We propose develop a new superimposition method the contours of and further evaluate feasibility. A total 270 intraoral scan models were collected from 135 subjects. After one‐year interval, 52 subjects chosen at random secondary obtained. first extracted form resource dataset test dataset. Through application...

Background: Osteotome sinus floor elevation is a less invasive approach to augment an insufficient alveolar bone at the posterior maxilla for dental implantation. However, this has some limitations due lack of lift tools available clinical use and small transcrestal access maxillary floor. We recently invented shape-memory Ni/Ti alloy wire containing tube elevators detaching mucosa, developed goat ex vivo models direct visualizing effectiveness mucosa in real time during elevation. Methods:...

The objective of this study was to comparatively evaluate 3 different sinus lift tools, namely umbrella-shaped curette YSL-04, our recently designed probe-improved curettes, and newly invented elevator 014, using previous developed goat ex vivo models for direct visualizing the effectiveness detaching mucosa in real time. Goat time were generated according previously protocol. each tool evaluated through length detached mesial distal directions or buccal palatal directions, space volume...