A5040610189- Gut microbiota and health
- Ruminant Nutrition and Digestive Physiology
- Probiotics and Fermented Foods
- Fermentation and Sensory Analysis
- Food Quality and Safety Studies
- Pharmacological Effects of Natural Compounds
- Vitamin K Research Studies
- Plant and fungal interactions
- Genetic and phenotypic traits in livestock
- Microbial Metabolism and Applications
- Environmental Toxicology and Ecotoxicology
- Anaerobic Digestion and Biogas Production
- Pesticide and Herbicide Environmental Studies
- Weed Control and Herbicide Applications
- Wastewater Treatment and Nitrogen Removal
- Biofuel production and bioconversion
- Aquaculture Nutrition and Growth
- Cancer Research and Treatments
- Mycotoxins in Agriculture and Food
- Pharmaceutical and Antibiotic Environmental Impacts
- Meat and Animal Product Quality
- Animal Nutrition and Physiology
- Lichen and fungal ecology
- GABA and Rice Research
- Food composition and properties
Taiyuan University of Science and Technology
2022-2025
Nanjing Agricultural University
2018-2024
Northwest A&F University
2023
Qilu Hospital of Shandong University
2021-2023
Beijing University of Technology
2022
Shanghai Jiao Tong University
2022
Chinese PLA General Hospital
2022
Nanjing Medical University
2022
Shandong University
2016-2021
Taiyuan University of Technology
2019-2020
Abstract Background Gastrointestinal tract (GIT) microbiomes in ruminants play major roles host health and thus animal production. However, we lack an integrated understanding of microbial community structure function as prior studies are predominantly biased towards the rumen. In this study, used shotgun metagenomics to profile microbiota 370 samples that represent 10 GIT regions seven ruminant species. Results Our analyses reconstructed a reference catalog with > 154 million...
The development of the rumen is an important physiological challenge for young ruminants. Previous studies have shown that starter feeding can effectively facilitate growth and in However, mechanism through which stimulates not clear. Here, we performed integrated analysis ruminal microbiota a host transcriptomic profile lamb model with intervention feed to understand microbiome-host crosstalk stimulating epithelium. Decreased pH increased acetate butyrate concentrations rumen, followed by...
Abstract Although the importance of bile acid (BA)-related microbial strains and enzymes is increasingly recognized for monogastric animals, a lack knowledge about BA metabolism in dairy cows limits functional applications aimed at targeted modulation microbe–host interactions animal production health. In present study, 108 content samples from six intestinal regions were used shotgun metagenomic sequencing. Overall, 372 high-quality metagenome-assembled genomes (MAGs) involved...
Abstract Background Methanomassiliicoccales are a recently identified order of methanogens that diverse across global environments particularly the gastrointestinal tracts animals; however, their metabolic capacities defined via limited number cultured strains. Results Here, we profile and analyze 243 genomes assembled from representatives uncultured metagenomes recovered various biomes, including different animal species. Our analyses reveal presence numerous undefined genera genetic...
The present study aimed to investigate the effects of sodium butyrate on intestinal barrier and mast cell activation, as well inflammatory mediator production, determine whether mitogen-activated protein kinase signaling pathways are involved in these processes. A total 72 piglets, weaned at 28 ± 1 d age, were allotted two dietary treatments (control vs. 450 mg/kg butyrate) for 2 wk. results showed that supplemental increased daily gain, improved morphology, indicated by greater villus...
In traditional fermentation process of Chinese strong-flavor liquor, composition, dynamic succession, and interaction microbial community in the fermented grains (FG) are fluctuant, resulting instability inconsistency liquor flavor quality. It is therefore important to reveal core microbiota FG from different pit ages layers cellars this study. Firstly, Venn analysis showed that 14 13 ubiquitous bacterial fungal genera were respectively observed. Meanwhile, Lactobacillus, Aquabacterium,...
Abstract Background B and K 2 vitamins, essential nutrients in host metabolism, can be synthesized by the rumen microbiome ruminants subsequently absorbed host. However, vitamin biosynthesis whole gastrointestinal their abundances different dietary strategies are largely unknown. Here, we reanalyzed our previous large-scale metagenomic data on of seven ruminant species recruited 17,425 nonredundant microbial genomes from published datasets to gain a comprehensive understanding...
Abstract Background The function of diverse ruminal microbes is tightly linked to rumen development and host physiology. system an excellent model clarify the fundamental ecological relationships among complex nutrient–microbiome–host interactions. Here, neonatal lambs are introduced different dietary regimes investigate influences early-life crosstalk between nutrients microbiome on development. Results We find starchy corn-soybean starter-fed exhibit thickest epithelia fiber-rich alfalfa...
Microplastics (MPs), as frequent pollutants, persist in aquatic environments and have an impact on the growth biomass production of microalgae. This study employed MPs polyethylene (PE), polystyrene (PS), polypropylene (PP) at concentrations 250 mg/L with MP sizes 50, 100, 300, 500 µm to investigate their influences bio-production Scenedesmus quadricauda. The results revealed that suppressed S. quadricauda increased algal lipid production. order terms inhibitory effect was following: PP >...
The cecum serves as an additional fermentation site for ruminants, but it lacks buffering capacity and has a relatively simple epithelial structure compared to the rumen. role of high-grain (HG) diets in manipulating rumen microbiome been well elucidated, yet microbial response such subsequent microbe-host interactions remain largely unexplored. Here, we describe modification cecal host gene expression based on data from 20 sheep grouped feed HG diet 7, 14, 28 days. Our indicate that...
Huangshui (HS), a by-product of solid-state fermentation Baijiu, is being given more attention on comprehensive utilization because its abundant microbial and nutritional resources. To effectively utilize HS for improving the economic benefits, correlations between community flavor compounds in different samples were uncovered present study. Lactobacillus, Methanobacterium, Methanobrevibacter, Methanoculleus, Methanosarcina dominant genera all samples. Additionally, Caproiciproducens...
Eleven new p-terphenyls, floricolins K–U (1–11), together with 13 biosynthetically related known compounds (12–24) were isolated from an endolichenic fungus, Floricola striata. Their structures elucidated by extensive spectroscopic analyses and single-crystal X-ray diffraction measurements. The newly p-terphenyls inhibited the growth of A2780, MCF-7, A549 cell lines. Further evaluation for multidrug resistance (MDR) reversal activity compound 5 revealed it enhanced sensitivity MCF-7/ADR...