A5072708651- Dementia and Cognitive Impairment Research
- Health disparities and outcomes
- Cardiovascular Health and Risk Factors
- Sleep and related disorders
- Healthcare Policy and Management
- Health, Environment, Cognitive Aging
- Aging and Gerontology Research
- Global Health Care Issues
- Sleep and Wakefulness Research
- Migration, Health and Trauma
- Nutritional Studies and Diet
- Obstructive Sleep Apnea Research
- Cardiac Health and Mental Health
- Neurobiology of Language and Bilingualism
- Geriatric Care and Nursing Homes
- Genetic Associations and Epidemiology
- Mental Health Treatment and Access
- Child and Adolescent Psychosocial and Emotional Development
- Primary Care and Health Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Stress Responses and Cortisol
- Diet and metabolism studies
- Hearing Loss and Rehabilitation
- Racial and Ethnic Identity Research
- Blood Pressure and Hypertension Studies
Wayne State University
2016-2025
San Diego State University
2012-2025
University of California, San Diego
2014-2024
Illinois College
2024
Office of Minority Health
2024
University of Illinois Chicago
2024
Brigham and Women's Hospital
2014-2023
Boston University
2023
Harbor–UCLA Medical Center
2023
Michigan United
2019-2023
To determine the prevalence and adequacy of depression care among different ethnic racial groups in United States.Collaborative Psychiatric Epidemiology Surveys (CPES) data were analyzed to calculate nationally representative estimates care.The 48 coterminous States.Household residents 18 years older (N = 15 762) participated study.Past-year pharmacotherapy psychotherapy using American Association guideline-concordant therapies. Depression severity was assessed with Quick Inventory...
We sought to examine and describe neurocognitive function among middle-aged older Hispanic/Latino Hispanic Community Health Study/Study of Latinos (HCHS/SOL) participants. analyzed baseline cross-sectional data from the (ages 45–74 years old) participants (n = 9,063) calculate scores their correlates. Older age higher depressive symptoms were associated with lower average performance, whereas greater educational attainment household income performance. heritage groups significantly varied in...
We estimated the prevalence and correlates of mild cognitive impairment (MCI) among middle-aged older diverse Hispanics/Latinos.Middle-aged Hispanics/Latinos enrolled (n = 6377; 50-86 years) in this multisite prospective cohort study were evaluated for MCI using National Institute on Aging-Alzheimer's Association diagnostic criteria.The overall was 9.8%, which varied between Hispanic/Latino groups. Older age, high cardiovascular disease (CVD) risk, elevated depressive symptoms significant...
<i>Objectives:</i> To examine the relationship between patients’ English proficiency, patient-provider language concordance, and health care quality among foreign-born Latinos in United States. <i>Methods:</i> National probability sample data (from Pew Hispanic Center/Robert Wood Johnson Foundation Latino Health Survey) were analyzed from telephone interviews with adults (n = 2921; aged 18 years older). There 3 main outcomes related to clinical experiences using self-reports of confusion,...
Abstract Introduction The aim was to examine associations between midlife cardiovascular health (CVH) and 20‐year cognitive decline among blacks whites. Methods Midlife CVH metrics (American Heart Association's Life's Simple 7) were calculated examined in relation change function 13,270 whites from the Atherosclerosis Risk Communities Cohort Study. We used linear mixed models estimate adjusted of with status change. Results Higher (Life's scores individual metrics, particularly blood...
Despite the joy of parenting, burden daily caregiving for children with autism spectrum disorders (ASD) can be overwhelming and constant. Parents expect to provide enduring care their ASD. Given that majority individuals remain in family homes well into adulthood, often need assistance activities living (ADLs) is placed on parents. Providing ongoing support adult who have difficulty completing ADLs increase parental demands. Therefore, purpose this study was examine relationship between...
<h3>Importance</h3> The Mediterranean diet may reduce the burden of Alzheimer disease and other associated dementias in Hispanic or Latino people. <h3>Objective</h3> To investigate association a with cognitive performance among community-dwelling adults. <h3>Design, Setting, Participants</h3> This cohort study analyzed data from Community Health Study/Study Latinos (HCHS/SOL) Study Latinos–Investigation Neurocognitive Aging (SOL–INCA), an HCHS/SOL ancillary study. Cognition tests were...
Hearing loss appears to have adverse effects on cognition and increases risk for cognitive impairment. These associations not been thoroughly investigated in the Hispanic Latino population, which faces hearing health disparities.
Cerebral white matter hyperintensities (WMH) on magnetic resonance imaging are part of the spectrum brain vascular injury accompanying aging and associated with an increased risk stroke dementia. WMH burden is greater among Hispanic than non-Hispanics (NHW) adults. highly heritable genome-wide association studies (GWAS) in older community-dwelling NHW African American (AA) individuals have identified several genetic loci. However, architecture Hispanic/Latino adults remains largely unknown....
Background: High adherence to the Mediterranean Diet (MeDi) was associated with better cognitive performance and decreased memory decline among Hispanic or Latino adults. Objective: Investigate if higher MeDi improves white matter (WM) integrity Hispanic/Latino adults this effect is mediated by cardiovascular health (CVH). Methods: We included 2,774 participants from Study of Latinos-Investigation Neurocognitive Aging-MRI Ancillary Study. Participants completed 24-hour dietary recalls at...
<b><i>Background/Aims:</i></b> To examine the cognitive reserve hypothesis by comparing contribution of early childhood and life course factors related to functioning in a nationally representative sample older Americans. <b><i>Methods:</i></b> We examined prospective, national probability cohort study (Health Retirement Study; 1998-2010) adults (n = 8,833) contiguous 48 United States. The main outcome was 35-point composite memory (recall),...
We evaluated the association between obstructive sleep apnea (OSA) and neurocognitive function among community-dwelling Hispanic/Latino individuals in United States.Cross-sectional analysis of Hispanic Community Health Study/Study Latinos middle-aged older adults, aged 45 to 74 years, with test scores at baseline measurements from 2008 2011. Neurocognitive were measured using Word Fluency (WF) Test, Brief-Spanish English Verbal Learning Test (SEVLT), Digit Symbol Substitution (DSS) Test. OSA...
Abstract Introduction Apolipoprotein E ( APOE ) alleles are associated with cognitive decline, mild impairment (MCI), and Alzheimer's disease in Whites, but have weaker inconsistent effects reported Latinos. We hypothesized that this heterogeneity is due to ancestry‐specific genetic effects. Methods investigated the associations of significant decline MCI 4183 Latinos, stratified by six Latino backgrounds, explored whether proportion continental ancestry (European, African, Amerindian)...
Background Cardiovascular disease (CVD) risk factors are highly prevalent among Hispanic/Latino adults, while the prevalence of MRI infarcts is not well-documented. We, therefore, sought to examine relationships between CVD and with brain structure individuals. Methods Participants included 1,886 adults (50–85 years) who underwent magnetic resonance imaging (MRI) as part Study Latinos—Investigation Neurocognitive Aging-MRI (SOL-INCA-MRI) study. was measured approximately 10.5 years before...
Abstract Background and Objectives While Hispanic/Latino populations in the U.S. are remarkably diverse terms of birthplace age at migration, we poorly understand how these factors associated with cognitive aging. Our research seeks to operationalize a life course perspective migration health contribute new understanding Alzheimer’s disease / related dementias among U.S.-based older adults. Research Design Methods Harnessing Hispanic Community Health Study/Study Latinos (n=16,415) Study...
This study examined the associations between anxious-depression symptoms with cognitive change and prevalent mild impairment (MCI) in middle-aged older Hispanics/Latinos. Participants were enrolled Study of Latinos-Investigation Neurocognitive Aging (SOL-INCA) Hispanic Community Health Study/Study Latinos (HCHS/SOL). Anxiety depression measured at Visit 1 using 10-item Spielberger State-Trait Inventory Center for Epidemiologic Studies Depression Scale, latent class analysis applied to derive...
BACKGROUND: Modifiable risk factors play a central role in the development and course of neurodegenerative disorders later life, including dementias. Although past research has focused on independent associations modifiable factors, cardiovascular disease using Framingham score, physical activity, dietary quality, body mass index, sleep, neurodegeneration, impact all 5 simultaneously multimodal model not been studied. We examined an overall combined with white matter injury, recognized...
Better cardiovascular health (CVH), measured using the Life's Simple 7 (LS7) score, is associated with improved cognitive function. However, its effect on brain imaging in Hispanics/Latinos has not been reported. We investigated association of LS7 score MRI outcomes a diverse Hispanic/Latino population. Hispanic Community Health Study/Study Latinos (HCHS/SOL) largest prospective cohort study adults United States. was assessed at baseline (2008-2011). The SOL-Investigation Neurocognitive...
BACKGROUND: Lp(a) (lipoprotein[a]) is a risk factor for cardiovascular disease; however, its association with cerebrovascular disease not as well established. METHODS: Data from population-based cohort of Hispanics/Latinos included 16 333 individuals baseline levels (nmol/L) and self-reported prevalent stroke or transient ischemic attack (TIA). A subset 2642 brain magnetic resonance imaging was also included. Linear multivariate logistic regression assessed the (1) TIA, (2) cerebral injury...