A5101595123- Advanced Polymer Synthesis and Characterization
- Block Copolymer Self-Assembly
- Silicone and Siloxane Chemistry
- Synthesis and properties of polymers
- Pluripotent Stem Cells Research
- CRISPR and Genetic Engineering
- Synthetic Organic Chemistry Methods
- Renal and related cancers
- Polyoxometalates: Synthesis and Applications
- Liquid Crystal Research Advancements
- Supramolecular Chemistry and Complexes
- Supercapacitor Materials and Fabrication
- Advanced Sensor and Energy Harvesting Materials
- Barrier Structure and Function Studies
- Synthesis and characterization of novel inorganic/organometallic compounds
- Glycosylation and Glycoproteins Research
- Liver Disease Diagnosis and Treatment
- Alcohol Consumption and Health Effects
- 3D Printing in Biomedical Research
- Advanced Battery Materials and Technologies
- Rheology and Fluid Dynamics Studies
- Advancements in Battery Materials
- Textile materials and evaluations
- Analytical Chemistry and Chromatography
- Conducting polymers and applications
Peking University
2008-2024
Beijing National Laboratory for Molecular Sciences
2014-2024
China Three Gorges University
2021
Ministry of Education
2015-2019
Jilin University
2016
Center for Life Sciences
2013
State Council of the People's Republic of China
2007
Shandong University
2007
Pluripotent stem cells can be induced from somatic cells, providing an unlimited cell resource, with potential for studying disease and use in regenerative medicine. However, genetic manipulation technically challenging strategies such as nuclear transfer used reprogramming limit their clinical applications. Here, we show that pluripotent generated mouse at a frequency up to 0.2% using combination of seven small-molecule compounds. The chemically resemble embryonic terms gene expression...
Hepatitis C virus (HCV) is a global challenge to public health. Several factors have been proven be critical for HCV entry, including the newly identified claudin-1 (CLDN1). However, mechanism of entry still obscure. Presently, among 20 members claudin family in humans so far, CLDN1 has only member shown necessary entry. Recently, we discovered that Bel7402, an HCV-permissive cell line, does not express but expresses other family. Among these claudins, CLDN9 was able mediate just as...
A series of brush block copolymers (BBCPs) with polynorbornene backbones containing poly{2,5-bis[(4-methoxyphenyl)oxycarbonyl]styrene} (PMPCS, which is a rigid chain) and poly(ethylene oxide) (PEO) side chains were synthesized by tandem ring-opening metathesis polymerizations. The weight fractions PEO in BBCPs are similar, the degrees polymerization (DPs) same while DPs PMPCS different. bulk self-assembling behaviors studied small-angle X-ray scattering (SAXS). neat cannot form ordered...
The self-assembly of a rod-coil amphiphilic block copolymer (ABCP) led to Im3‾ m and Pn3‾ polymer cubosomes p6mm hexasomes. This is the first time that these structures are observed in system. By varying hydrophobic chain length, initial concentration solution, or solubility parameter mixed solvent, head-tail asymmetry adjusted control formation mechanism was also studied. research opens up new way for further study bicontinuous inverse phases different ABCP systems.
We synthesized a new series of MJLCPs with polynorbornene main chain, PNbnPT (n = 8, 10, 12, 14, 16, 18, which is the number carbons in side-chain alkyl tails), through ring-opening metathesis polymerization and investigated their phase behaviors. The monomers were facilely satisfactory yields key intermediate, N-(2,5-dicarboxylphenyl)-cis-5-norbornene-exo-2,3-dicarboximide. Differential scanning calorimetry, polarized light microscopy, wide-angle X-ray diffraction results demonstrate that...
A series of organic–inorganic hybrid polymers, PnPOSS (n = 6, 10, which is the number carbon atoms in flexible alkyl spacers), containing a mesogen-jacketed liquid crystalline polymer (MJLCP) as main chain and nanobuilding block, polyhedral oligomeric silsesquioxane (POSS), side chains were designed synthesized for constructing inclusion complex. The phase structures transitions investigated by differential scanning calorimetry, polarized light microscopy, wide-angle X-ray diffraction,...
A polynorbornene-based mesogen-jacketed liquid crystalline polymer containing side-chain POSS moieties was synthesized through ROMP. It self-assembles into an organic–inorganic hybrid inclusion complex on the sub-10 nm scale.
MJLCPs with a polynorbornene main chain and different side groups have been precisely synthesized for investigating the effect of side-chain structures on liquid crystalline phase behaviors.
A series of main-chain/side-chain combined liquid crystalline polymers (MCSCLCPs) with a polynorbornene backbone and multi-benzene mesogens in the side chain, PNbnPP (n = 2, 6, 10), were synthesized through controllable polymerization method: ring-opening metathesis (ROMP). Differential scanning calorimetry, polarized light microscopy, one-/two-dimensional wide-angle X-ray diffraction utilized to investigate phase behavior PNbnPP. Experimental results reveal that two fundamentally different...
Supramolecular liquid crystalline block copolymers prepared <italic>via</italic> hydrogen bonding exhibit hierarchical structures that can be tuned by varying the molar ratio of discotic hydrogen-bonding acceptor to copolymer donor.
Obtaining nanoscale-ordered structures is important for the development of nanotechnology. We designed and synthesized a series disk-cube triads containing one hexa-peri-hexabenzocoronene (HBC) two polyhedral oligomeric silsesquioxane (POSS) moieties, HBC-2POSS. The POSS units were linked via ester or amide bonds. With linkage used, hydrogen bonding that was introduced affected balance between π-π interaction HBC cores crystallization units. Hierarchically ordered obtained from HBC-2POSS...
In order to investigate the factors affecting hierarchically ordered structures of rod–rod block copolymers, SmPn based on two polynorbornene-based mesogen-jacketed liquid crystalline (LC) polymers PNb12POSS [having side-chain polyhedral oligomeric silsesquioxane (POSS) units] and PNb10PP (with a calamitic mesogen) was designed synthesized by ring-opening metathesis polymerization, in which S P refer segments PNb10PP, respectively, whereas m n ratios monomer catalyst during polymerization...
Abstract The self‐assembly of a rod–coil amphiphilic block copolymer (ABCP) led to Im m and Pn polymer cubosomes p6mm hexasomes. This is the first time that these structures are observed in system. By varying hydrophobic chain length, initial concentration solution, or solubility parameter mixed solvent, head–tail asymmetry adjusted control formation mechanism was also studied. research opens up new way for further study bicontinuous inverse phases different ABCP systems.