Ifeoluwakiisi Adejoorin

ORCID: 0000-0001-8967-5896
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About
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Research Areas
  • Systemic Lupus Erythematosus Research
  • T-cell and B-cell Immunology
  • Cancer Immunotherapy and Biomarkers
  • SARS-CoV-2 and COVID-19 Research
  • CAR-T cell therapy research
  • Rheumatoid Arthritis Research and Therapies
  • Dermatological and COVID-19 studies
  • interferon and immune responses
  • Monoclonal and Polyclonal Antibodies Research
  • Cytokine Signaling Pathways and Interactions
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Immunotherapy and Immune Responses

Brigham and Women's Hospital
2022-2025

Harvard University
2023-2024

Immune checkpoint inhibitor (ICI) therapies used to treat cancer, such as anti–PD-1 antibodies, can induce autoimmune conditions in some individuals. The T cell mechanisms mediating iatrogenic autoimmunity and their overlap with spontaneous diseases remain unclear. Here, we compared cells from the joints of 20 patients an inflammatory arthritis induced by ICI therapy (ICI-arthritis) two archetypal arthritides, rheumatoid (RA) psoriatic (PsA). Single-cell transcriptomic antigen receptor...

10.1126/sciimmunol.add1591 article EN Science Immunology 2023-07-28
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