A5002096365- Cardiac Ischemia and Reperfusion
- Alcohol Consumption and Health Effects
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroscience and Neuropharmacology Research
- Eicosanoids and Hypertension Pharmacology
- Glaucoma and retinal disorders
- Cancer, Hypoxia, and Metabolism
- Neurological Disease Mechanisms and Treatments
- Cancer Mechanisms and Therapy
- Cancer Treatment and Pharmacology
- Anesthesia and Neurotoxicity Research
- Epigenetics and DNA Methylation
- Corneal surgery and disorders
- Angiogenesis and VEGF in Cancer
- Traditional Chinese Medicine Analysis
- Estrogen and related hormone effects
- Retinal Diseases and Treatments
- Cancer, Stress, Anesthesia, and Immune Response
- Inflammatory mediators and NSAID effects
- Chromatography in Natural Products
- Retinal and Macular Surgery
- MicroRNA in disease regulation
- Neurological Disorders and Treatments
- Phytochemistry and Bioactive Compounds
- Extracellular vesicles in disease
Yixing People's Hospital
2025
Jiangsu University
2025
Eye & ENT Hospital of Fudan University
2022-2024
Integrated Chinese Medicine (China)
2021-2024
Louisiana State University Health Sciences Center Shreveport
2017-2024
Fudan University
2015-2024
Beijing Chest Hospital
2024
Capital Medical University
2023-2024
Beijing Geriatric Hospital
2023
Nanjing Medical University
2006-2022
<h3>Background</h3> The rapid spread of multidrug-resistant tuberculosis (MDR-TB) has attracted global concerns. This study aimed to identify factors contributing the high prevalence MDR-TB in China9s Heilongjiang province. <h3>Methods</h3> A cross-sectional survey following WHO/International Union Against Tuberculosis and Lung Disease guidelines was conducted with consecutive recruitment patients TB 30 counties selected at random 2004. total 1995 were tested for MDR-TB. Factors associated...
Background: Recently, internet hospitals have been emerging in China, saving patients time and money during the COVID-19 pandemic. In addition, pharmacy services that link doctors are becoming essential improving patient satisfaction. However, existing hospital service mode relies primarily on manual operations, making it cumbersome, inefficient, high-risk. Objective: To establish an based artificial intelligence (AI) provide new insights into Methods: An AI-based was established. Initially,...
Peripheral neuropathy is the major dose-limiting side effect of paclitaxel (PTX), affecting both quality life and survival cancer patients. Nab-paclitaxel (nab-PTX) was developed to provide additional clinical benefits overcome safety drawbacks solvent-based PTX. However, prevalence peripheral induced by nab-PTX reported higher than that Upon investigation, oxidative stress plays a role in toxicity nab-PTX. In order assess if antioxidant alphalipoic acid ( α -LA) could prevent...
Salvianolic acid A (Sal A), the water-soluble component from root of Salvia miltiorrhiza plant, possesses antioxidant, antiproliferative, and antiplatelet properties. However, whether it plays a role in protection against ischemia–reperfusion (I/R) injury rat hearts has yet to be elucidated. In present study, we tested cell viability, shortening amplitude, necrosis, apoptosis, expression levels Akt, phosphorylated Bcl-2, Bax, caspase-3 after 3-hour simulated ischemia 2- or 6-hour reperfusion...
Chronic ethanol consumption dose-dependently affects both incidence and prognosis of ischemic stroke. Our goal was to determine whether the influence chronic on stroke is related an altered inflammatory profile in brain. Male C57BL/6J mice were divided into six groups gavage fed with 0.175, 0.35, 0.7, 1.4, 2.8 g/kg/day or volume-matched water once a day for 8 weeks. Adhesion molecules, microglial activation, neutrophil infiltration, pro- anti-inflammatory cytokines/chemokines, blood-brain...
Abstract It has been reported that tripartite motif containing 26 (TRIM26) is involved in the tumorigenesis of some cancers, but its function non‐small cell lung cancer (NSCLC) still unclear. In this study, we found TRIM26 was markedly down‐regulated both NSCLC tumor tissues and lines. Additionally, high expression patients predicted a positive index for patients' overall survival. What more, overexpression significantly suppressed growth. Our further studies indicated inhibited...
Objectives The study was intended to investigate which commonly used anesthetic in intact animals has the least effect on function of isolated hearts and cardiomyocytes among anesthetized animals. Methods male Sprague–Dawley rats were removed after they with ketamine, chloral hydrate or pentobarbital sodium, respectively, cervically dislocated. They mounted a Langendorff shelf. Heart rate (HR), left ventricular systolic pressure (LVSP), maximal increase (+dp/dt) observed recorded. Cell...
Increasing evidence suggest that low-dose alcohol consumption (LAC) reduces the incidence and improves functional outcome of ischemic stroke. We determined influence LAC on post-ischemic inflammation. Male Sprague-Dawley rats were divided into 3 groups, an ethanol (13.5% alcohol) group, a red wine (Castle Rock Pinot Noir, 13.5% control group. The amount given to groups was 1.4 g/kg/day. After 8 weeks, animals subjected 2-hour middle cerebral artery occlusion (MCAO) sacrificed at 24 hours...