A5080456789- Reconstructive Surgery and Microvascular Techniques
- Burn Injury Management and Outcomes
- Multiple Myeloma Research and Treatments
- Global Cancer Incidence and Screening
- Anesthesia and Pain Management
- Wound Healing and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Chronic Lymphocytic Leukemia Research
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Lung Cancer Research Studies
- Lymphoma Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Renal Transplantation Outcomes and Treatments
- Multiple and Secondary Primary Cancers
- Catalytic C–H Functionalization Methods
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Delphi Technique in Research
- Spine and Intervertebral Disc Pathology
- ECG Monitoring and Analysis
- Airway Management and Intubation Techniques
- Catalytic Cross-Coupling Reactions
- Healthcare Technology and Patient Monitoring
- Cancer Treatment and Pharmacology
Tufts Medical Center
2020-2025
Peking University
2000-2025
Peking University Cancer Hospital
2025
MaineHealth
2025
Beijing Jishuitan Hospital
2000-2023
Third Affiliated Hospital of Sun Yat-sen University
2020-2021
Sun Yat-sen University
2020-2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2020
Peking Union Medical College Hospital
2017-2018
Yale University
2016-2017
Immune-checkpoint inhibitors (ICIs) have revolutionized lung cancer (LC) treatment; however, immune-related adverse effects (irAEs) may occur. The risk factors of irAEs and the impact on patient outcomes in LC remain uncertain. within 12 months ICI initiation patients who initiated ICIs 2018-2021 were identified. Cause-specific Cox regression was used to assess for with competing death; a subset analysis done among non-small cell (NSCLC) group. Multivariable regressions evaluate...
ABSTRACT Background and objective Lung function tests are widely used in clinical public health practice; however, no valid spirometry reference values were available for the general population China. This study aimed to provide predictive equations China, evaluate performance of previously equations. Methods Data from China National Health Survey 2012–2015 ‘Generalized Additive Models Location, Scale Shape’ statistical modelling method establish forced expiratory volume 1 s ( FEV ), vital...
Ischemia reperfusion injury (IRI) is a major challenge for renal transplantation. This study was performed to explore the mechanisms and potential molecular targets involved in IRI. In this study, gene datasets GSE43974 GSE126805 from Gene Expression Omnibus database, which include ischemic reperfused specimens, were analyzed determine differentially expressed genes (DEGs). ontology annotations, Kyoto Encyclopedia of Genes Genomes analysis, set enrichment analysis pathways that are...
A ruthenium-catalyzed sulfonamide-directed ortho aryl C-H alkenylation/annulation to afford five-membered sultam by using of molecular oxygen as an oxidant is reported in this article. Compared the previous transition-metal-catalyzed alkenylation sulfonamides, no excess metal salt was required method. wide sulfonamide substrates scope and good regioselectivity site-selectivity make Ru-catalyzed method more attractive. Importantly, can not only be used effectively prepare biologically active...
The data on immune checkpoint inhibitors (ICI) use in lung cancer individuals generally underrepresented clinical trials are limited. We aimed to examine the ICI access, safety, and outcome these populations using real-world data. Patients with newly started ICIs from 2018 2021 were included. Patient factors (age, sex, race, insurance, Charlson comorbidity index (CCI), Eastern Cooperative Oncology Group (ECOG) performance status, histories of autoimmune disease (AD), infection within 3...
Spirometry reference values specifically designed for Asian Americans are currently unavailable. The performance of Global Lung Function Initiative 2012 (GLI-2012) equations on assessing spirometry in has not been evaluated. This study aimed to assess the fitness relevant GLI-2012 Americans. subjects who never smoked and had qualified data were extracted from National Health Nutrition Examination Survey (NHANES) 2011–2012. Z-scores forced expiratory volume 1 s (FEV1), vital capacity (FVC),...
Higher dose of palonosetron versus lower plus droperidol to prevent postoperative nausea and vomiting after eye enucleation orbital hydroxyapatite implant surgery: a randomized, double-blind trial Xiao Hu, Fang Tan, Lan Gong Department Anesthesiology, The Eye, Ear, Nose Throat Hospital Fudan University, Shanghai Medical College Shanghai, China Objective: Postoperative (PONV) is commonly observed surgery. This prospective, was conducted investigate the hypothesis that compared with...
The aim of the present study was to report a failed inhalation induction anesthesia with sevofluran in pediatric patient grade III laryngeal obstruction caused by papillomatosis. Inhalation is recommended for patients. In case, due respiratory depression properties anesthetics, partial airway developed into complete obstruction, followed cardiac arrest. survived after surgeon managed reconvert through removal part papillomas. conclusion, reaction case sevoflurane suggests that this technique...
Abstract Background Data on the care of Asian patients with lung cancer in US are limited; however, is leading cause death this population. Methods Demographics, low-dose computed tomography (LDCT) screening, disease characteristics, and treatment history were compared between White newly diagnosed from 2014 to 2019 identified Tufts Medical Center registry. The influence race presenting stage was assessed via ordinal logistic regression. Time initiation (TTI) overall survival (OS) analyzed...
115 Background: Cancer is the leading cause of death in Asian Americans (AA), fastest growing racial/ethnic group US. Lung cancer a diagnosis and AA. Yet data on quality lung care AA are limited. This retrospective study examines racial disparities at an urban academic medical center serving large proportion patients. Methods: Newly diagnosed patients with from 01/01/2014 to 12/31/2019 were identified Tufts Medical Center registry; clinical collected through 05/31/2022. Patient demographics,...
Objectives: We aimed to analyze the effect of cold ischemia time (CIT) on post-transplant graft function through mixed-effect model analysis reduce bias caused by paired mate kidneys. Methods: reviewed all kidney transplantation records from 2015 2019 at our center. After applying exclusion criteria, 561 cases were included for analysis. All donor characteristics, preservation and matching information, recipient characteristics collected. Transplant outcomes delayed (DGF) estimated...
12130 Background: Immune checkpoint inhibitors (ICIs) have emerged as a core pillar of lung cancer (LC) therapy, but ICIs are commonly associated with spectrum immune-related adverse effects (irAEs). The real-world patterns and risk factors irAEs in LC remain uncertain. Methods: Patients newly started on between 10/01/2018 09/30/2021 were retrospectively collected from the Tufts Medical Center registry pharmacy records. occurring within 12 months after initiation identified. Univariable...
To explore the expression pattern and clinical significance of TEAD1 in hepatocellular carcinoma (HCC). The prognostic TEAD-1 is also evaluated.TEAD1 was detected by immunohistochemistry (IHC) method western blot. association between HCC tissues variables evaluated Chi-squared test. Survival analysis used to determine prognosis effect TEAD1.Expression significantly increased compared with adjacent normal liver IHC (p = 0.002) blot 0.020). difference for ratio low, medium, high staining...
Objective: To investigate the effects of flap or myocutaneous combined with fascia lata composite mesh on repairing wounds in abdomen patients severe high-voltage electrical burn. Methods: From January 2010 to May 2017, 11 burn were hospitalized our wards. In 3 hours 7 days after burn, operation was performed when stable condition. After debridement, intestines necrosis perforation 4 peritoneal defects resected and intestinal anastomosis performed. The size abdominal debridement ranged from...