- Advanced Sensor and Energy Harvesting Materials
- Neuroscience and Neural Engineering
- Muscle activation and electromyography studies
- EEG and Brain-Computer Interfaces
- Advanced Materials and Mechanics
- Conducting polymers and applications
- Tactile and Sensory Interactions
- Spinal Cord Injury Research
- Photoreceptor and optogenetics research
- Dielectric materials and actuators
- Nerve injury and regeneration
- Advanced Memory and Neural Computing
- Transcranial Magnetic Stimulation Studies
- Nanomaterials and Printing Technologies
- Surface Modification and Superhydrophobicity
- 3D Printing in Biomedical Research
- Adhesion, Friction, and Surface Interactions
- Neural dynamics and brain function
- Neurological disorders and treatments
- Nerve Injury and Rehabilitation
- Thin-Film Transistor Technologies
- Vagus Nerve Stimulation Research
- Hearing Loss and Rehabilitation
- Organic Electronics and Photovoltaics
- Hearing, Cochlea, Tinnitus, Genetics
École Polytechnique Fédérale de Lausanne
2015-2024
Wyss Center for Bio and Neuroengineering
2016-2023
Bioengineering (Switzerland)
2023
Bioengineering Center
2021
ORCID
2020
Lawrence Berkeley National Laboratory
2018-2019
Ben-Gurion University of the Negev
2018-2019
Interface (United States)
2019
University of California, Berkeley
2018-2019
Fondation Bertarelli
2019
The mechanical mismatch between soft neural tissues and stiff implants hinders the long-term performance of implantable neuroprostheses. Here, we designed fabricated with shape elasticity dura mater, protective membrane brain spinal cord. electronic which call e-dura, embeds interconnects, electrodes, chemotrodes that sustain millions stretch cycles, electrical stimulation pulses, chemical injections. These integrated modalities enable multiple neuroprosthetic applications. extracted...
Stripes of thin gold films are made on an elastomeric substrate with built-in compressive stress to form surface waves. Because these waves can be stretched flat they function as elastic electrical conductors. Surprisingly, we observe continuity not only up external strain ∼2% reached by stretching the first (∼0.4%) and then fracture free-standing (∼1%), but ∼22%. Such large strains will permit making stretchable electric conductors that essential three-dimensional electronic circuits.
Elastic electronic surfaces will integrate stiff thin film devices onto compliant polymer substrates. These may be stretched once or many times, by up to tens of percent strain. One way make such an elastic surface is distribute rigid subcircuit islands over the surface, and then fabricate active on islands. need interconnected with stretchable metallization. We describe interconnects made stripes gold patterned elastomeric membranes. membranes can twice their initial length maintain...
Gold films on an elastomeric substrate can be stretched and relaxed reversibly by tens of percent. The initially form in two different structures, one continuous the other containing tribranched microcracks. We have identified mechanism elastic stretchability with metal, which is much stiffer than elastomer, forms a percolating network. To accommodate large elongation substrate, metal network twists deflects out plane but remains bonded to soft substrate. Consequently, film experiences only...
This report demonstrates a wearable elastomer‐based electronic skin including resistive sensors for monitoring finger articulation and capacitive tactile pressure that register distributed along the entire length of finger. Pressure sensitivity in order 0.001 to 0.01 kPa −1 pressures from 5 405 kPa, which includes much range human physiological sensing, is achieved by implementing soft, compressible silicone foam as dielectric stretchable thin‐metal films. Integrating these textile glove...
Stretchable biphasic conductors are formed by physical vapor deposition of gallium onto an alloying metal film. The properties the photolithography-compatible thin films highlighted low sheet resistance (0.5 Ω sq(-1) ) and large stretchability (400%). This novel approach to deposit pattern liquid metals enables extremely robust, multilayer soft circuits, sensors, actuators.
Abstract A spinal cord injury interrupts pathways from the brain and brainstem that project to lumbar cord, leading paralysis. Here we show spatiotemporal epidural electrical stimulation (EES) of 1–3 applied during neurorehabilitation 4,5 (EES REHAB ) restored walking in nine individuals with chronic injury. This recovery involved a reduction neuronal activity humans walking. We hypothesized this unexpected reflects activity-dependent selection specific subpopulations become essential for...
Epidural electrical stimulation (EES) of lumbosacral sensorimotor circuits improves leg motor control in animals and humans with spinal cord injury (SCI). Upper-limb involves similar circuits, located the cervical cord, suggesting that EES could also improve arm hand movements after quadriplegia. However, ability to selectively modulate specific upper-limb nuclei remains unclear. Here, we combined a computational model experiments macaque monkeys explore mechanisms motoneuron recruitment...
Many flexible electronic surfaces comprise inorganic films on organic substrates. Mechanical failure of such integrated structures stiff and compliant materials poses a significant challenge. This letter studies the stretchability metal elastomer Our experiment shows that, when stretched, elastomer-supported rupture at strains larger than those reported for freestanding films. We use finite element code to simulate process A film ruptures by forming single neck. By contrast, an substrate may...
We prepare stretchable electrical conductors of 25-nm-thick gold films on elastomeric substrates prestretched by 15%. When the relax from prestretch, stripes form surface waves with /spl sim/8.4-μm wavelength and sim/1.2-μm amplitude. strain is cycled between 0 15%, both wave pattern resistance change in reproducible cycles. Such repeatedly metallization can serve as interconnects for skin-like, conformal, electroactive polymer circuits.
We present a stretchable and multifunctional capacitive sensor made of gold thin films embedded in silicone rubber. The mechanical compliance the membranes allow device to be bent, folded, or stretched without damage, making it suitable candidate for electronic skin applications. can detect strains up 20%, human touch, pressure 160 kPa, reliably function when is held relaxed.
Gold thin-films (50 nm thick) on silicone membranes are reversibly stretchable. They exhibit continuous electrical conduction when pulled and relaxed by tens of percent. Here, we show that gold thin-film conductors elastomeric substrates can withstand extensive uniaxial stretch cycling without failure. The film develops into an interconnected network islands, which move the surface elastomer with applied strain. resulting resistance conductor remains finite reproducible over 250 000 cycles to 20%
A monolithically integrated bifunctional frontplane is introduced to large area electronics. The element based on a composite foil of piezoelectric ceramic lead titanate nanoparticles embedded in ferroelectric poly(vinylidene fluoride trifluoroethylene) polymer matrix. Bifunctionality pressure and temperature changes achieved by sequential, selective two-step poling process, where the polarization directions are adjusted independently. Thereby, sensor elements that only or pyroelectric...
Ferroelectrets generate an electric field large enough to modulate the conductance of source-drain channel a thin-film field-effect transistor. Integrating ferroelectret with transistor produces The authors made such transistors by laminating cellular polypropylene films and amorphous silicon on polyimide substrates. They show that these ferrroelectret respond in static capacitive or dynamic piezoelectric mode. A touch sensor, pressure-activated switch, microphone are demonstrated. structure...
Stretchable gold conductors embedded in polydimethylsiloxane (PDMS) films were successfully prepared using standard photolithography. The minimum feature sizes patterned the metal film and PDMS encapsulation are 10 µm 20 µm, respectively. micro-patterned robust to uni-axial (1D) radial (2D) stretching with applied strains of tens percent. electrical response follows a nonlinear increase strain, is reversible. extensive stretchability relies on randomly independently distributed network...