A5008722736- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Pregnancy and Medication Impact
- Anesthesia and Pain Management
- Pharmacological Effects and Toxicity Studies
- Anesthesia and Sedative Agents
- Pregnancy-related medical research
- Birth, Development, and Health
- Maternal Mental Health During Pregnancy and Postpartum
- Maternal and Perinatal Health Interventions
- Cardiovascular Issues in Pregnancy
- Obesity, Physical Activity, Diet
- Maternal and fetal healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Global Maternal and Child Health
- Electrolyte and hormonal disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and Neonatal Healthcare
- Alcoholism and Thiamine Deficiency
- Pancreatic function and diabetes
- Neonatal Respiratory Health Research
- Reproductive Health and Contraception
- Ovarian function and disorders
- Nutritional Studies and Diet
- Prenatal Substance Exposure Effects
Universidade de São Paulo
2015-2024
Universidade de Ribeirão Preto
2005-2024
Seevic College
2021
Universidade Federal de São Carlos
2012
Objective To generate a global reference for caesarean section ( CS ) rates at health facilities. Design Cross‐sectional study. Setting Health facilities from 43 countries. Population/Sample Thirty eight thousand three hundred and twenty‐four women giving birth 22 countries model building 10 045 875 testing. Methods We hypothesised that mathematical models could determine the relationship between clinical‐obstetric characteristics . These generated probabilities of be compared with observed...
There is an urgent need to find consensus on screening, diagnosing and treating all degrees of dysglycemia that may occur during pregnancies in Brazil, considering many cases pregnant women are currently not diagnosed, leading maternal fetal complications. For this reason the Brazilian Diabetes Society (SBD) Federation Gynecology Obstetrics Societies (FEBRASGO), got together introduce proposal. We present here a joint regarding standardization clinical management for with any degree...
A sensitive, selective, and reproducible in‐tube solid‐phase microextraction liquid chromatographic (in‐tube SPME/LC‐UV) method for determination of lidocaine its metabolite monoethylglycinexylidide (MEGX) in human plasma has been developed, validated, further applied to pharmacokinetic study pregnant women with gestational diabetes mellitus (GDM) subjected epidural anesthesia. Important factors the optimization SPME performance are discussed, including draw/eject sample volume, cycle...
The aim of this study is to determine the concentrations lidocaine and its metabolite, monoethylglycine xylidide (MEGX), enantiomers bupivacaine in maternal fetal compartments. Ten healthy pregnant women were submitted epidural anesthesia. Drug determined vein, umbilical artery placental intervillous space. highest MEGX metabolite detected plasma transfer was 33% for (+)-(R)-bupivacaine enantiomer 31% (-)-(S)-bupivacaine enantiomer. For respective transfers 60% 43%. Lidocaine concentration...
Aims Diabetes mellitus can inhibit cytochrome P450 3A4, an enzyme responsible for the metabolism of nifedipine, used treatment hypertension in pregnant women. We aimed to assess effect type 2 diabetes (T2DM) on pharmacokinetics, placental transfer and distribution nifedipine amniotic fluid hypertensive Methods The study was conducted 12 women [control group (CG)] 10 with T2DM taking slow‐release (20 mg, 12/12 h). On 34th week gestation, serial blood samples were collected (0–12 h) after...
Aim To investigate the influence of gestational diabetes mellitus ( GDM ) on kinetic disposition and transplacental amniotic fluid distribution metoprolol its metabolites O ‐desmethylmetoproloic acid α‐hydroxymetoprolol stereoisomers in hypertensive parturients receiving a single dose racemic drug. Methods The study was conducted with well‐controlled n = 11) non‐diabetic 24), all 100 mg oral tartrate before delivery. Serial maternal blood samples (0–24 h) umbilical were collected for...
Nutrition during pregnancy influences perinatal outcomes and predispositions to chronic diseases. A prospective cohort study was carried out with the objectives of describing dietary patterns in pregnant population city Quito, Ecuador analysing sociodemographic lifestyle factors that influence adherence each pattern. The body mass index calculated for patient, patients were classified according Atalah criteria. Global Physical Activity Questionnaire also applied. assessed using a survey 24 h...
To identify sociodemographic and reproductive risk factors associated with MetS in women their fourth decade of life.
Disrespectful and abusive treatment of women during childbirth is a worldwide problem. This research aimed to develop implement Mother Baby-Friendly Hospital Initiative (MBFHI) in an academic maternity hospital Brazil evaluate how change could be sustained. Change Laboratory principles guided process action research, which was conducted between 2017 2019. Clinicians managers joined the researchers discussion sessions redesign routines care pathways. Observation, interviews, focus groups,...
Here, we describe the case of a patient diagnosed with locally advanced breast cancer 8 years ago. Her treatment course was neoadjuvant chemotherapy, followed by mastectomy and then adjuvant radiotherapy trastuzumab (TTZ). During use targeted therapy, an incidental pregnancy diagnosed. Four later, she developed bone cerebral metastases, since then, has received courses TTZ, capecitabine, lapatinib, intermittent control disease. 7-year-old son presents normal physical long-term neurological...
Obesity and lack of physical exercise are associated with the increase diabetes mellitus in women reproductive age during gestational period. The objective present study was to evaluate activity levels pregnancy postpartum periods influence body mass index (BMI) (GDM) or low risk pregnancy. Pregnancy Physical Activity Questionnaire (PPAQ), translated validated for Portuguese, used evaluation (PA) level. sample stratified according preconception BMI presence absence diagnosis GDM, resulting...