Janina Brucker

ORCID: 0000-0001-9101-3402
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About
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Research Areas
  • Cervical Cancer and HPV Research
  • Endometrial and Cervical Cancer Treatments
  • Ovarian cancer diagnosis and treatment
  • Ectopic Pregnancy Diagnosis and Management
  • Intraperitoneal and Appendiceal Malignancies
  • Angiogenesis and VEGF in Cancer
  • Sex and Gender in Healthcare
  • Pelvic floor disorders treatments
  • Urinary Bladder and Prostate Research
  • Genital Health and Disease
  • Urinary Tract Infections Management
  • Animal health and immunology
  • Vascular Tumors and Angiosarcomas
  • Congenital Anomalies and Fetal Surgery
  • Historical Gender and Feminism Studies
  • Global Cancer Incidence and Screening
  • Renal and related cancers
  • Reproductive tract infections research
  • MRI in cancer diagnosis
  • Atherosclerosis and Cardiovascular Diseases
  • Gestational Trophoblastic Disease Studies
  • Iron Metabolism and Disorders
  • Cytokine Signaling Pathways and Interactions
  • dental development and anomalies
  • Assisted Reproductive Technology and Twin Pregnancy

Heidelberg University
2015-2020

University Hospital Heidelberg
2015-2020

Frauenklinik Heidelberg
2016-2018

University of Münster
1985

Institutul Cantacuzino
1969

Introduction Vaginal intraepithelial neoplasia (VAIN) is a pre-malignant lesion, potentially leading to vaginal cancer. It rare disease, representing less than 1% of all the female genital tract. Similar cervical (CIN), there are three different grades VAIN. VAIN 1 also known as low-grade squamous lesion (LSIL), whereas 2 and 3 both represent high-grade lesions (HSIL). Risk factors for development similar those neoplasia, i.e. promiscuity, starting sexual activity at an early age, tobacco...

10.1371/journal.pone.0167386 article EN cc-by PLoS ONE 2016-12-01

Patients with non-platinum-sensitive recurrent ovarian cancer have a poor prognosis. Non-pegylated liposomal doxorubicin (Myocet®) is promising drug that may be able to improve treatment for such patients. In the current study, patients relapsing within 12 months after primary received non-pegylated at 75 mg/m2 d1q22 and 60 study dose modification, respectively. There were 29 enrolled in trial, 124 cycles of administered total. All evaluable toxicity. The clinical benefit rate (defined as...

10.3892/ol.2016.4740 article EN Oncology Letters 2016-06-16

Background MRI with contrast material enhancement is the imaging modality of choice to evaluate sonographically indeterminate adnexal masses. The role diffusion-weighted MRI, however, remains controversial. Purpose To diagnostic performance ultra-high-b-value diffusion kurtosis in discriminating benign and malignant ovarian lesions. Materials Methods This prospective cohort study evaluated consecutive women masses between November 2016 December 2018. at 3.0 T was performed, including (b...

10.1148/radiol.2020191700 article EN Radiology 2020-06-16

Cancer patients have a higher risk for thromboembolic events compared to healthy individuals and are often treated with heparins. A beneficial effect of heparins on tumor above beyond the classic anticoagulation has been reported, leading an increased focus use in anticancer treatment. In recent years, it become apparent that microenvironments greatly affect development can be major source tumor-promoting factors. Cytokines play important role microenvironments, inducing carcinogenesis...

10.1055/s-0043-119289 article DE cc-by Geburtshilfe und Frauenheilkunde 2017-10-01

A 24-year-old woman, who had undergone neither fertility treatment nor uterine surgery other than a cesarean section, presented with an intramural ectopic pregnancy. laparotomy wedge resection including the embryonic tissue was performed. The postoperative course uneventful, falling βHCG levels. Two months after she again intrauterine

10.1016/j.crwh.2020.e00215 article EN cc-by-nc-nd Case Reports in Women s Health 2020-05-06

Hintergrund: Die Konisation ist eine der häufigsten gynäkologischen Eingriffe. Sie erfolgt bei Verdacht auf oder bereits histologisch gesicherter höhergradiger Dysplasie. Infolge können sowohl physische als auch psychische Beschwerden auftreten. Beispielsweise kann es zu einem erhöhten Risiko für Frühgeburten, Vernarbungen und Dyspareunie kommen. Weiterhin werden die Frauen durch Sorge einer erneuten Dysplasie Entstehung eines Zervixkarzinoms belastet. Dies in Literatur nur unzureichend...

10.1055/s-0036-1571384 article DE Geburtshilfe und Frauenheilkunde 2016-02-29

Zielsetzung: Die Konisation ist eine der häufigsten gynäkologischen Eingriffe. Infolgedessen können physische und psychische Beschwerden auftreten. Durch die Studie sollen Sorgen Beeinträchtigungen nach einer sowie Relevanz guten Nachbetreuung objektiviert werden. Ziel ist, individualisierte Nachsorgeempfehlungen herauszuarbeiten so zur Verbesserung Frauengesundheit beizutragen.

10.1055/s-0036-1593044 article DE Geburtshilfe und Frauenheilkunde 2016-10-13

Anamnese Eine 24jährige Patientin IIGIP (Z.n. Sectio 07/19) in rechnerisch 8+3SSW ohne relevante Vorerkrankungen wurde uns mit Verdacht auf EUG im Isthmus tubae links aus einem Kreiskrankenhaus zu verlegt.

10.1055/s-0040-1718303 article DE Geburtshilfe und Frauenheilkunde 2020-10-01
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