A5100407583- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Disease and Adiposity
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Cardiovascular Effects of Exercise
- Cardiovascular Health and Disease Prevention
- HIV Research and Treatment
- Liver Disease and Transplantation
- HIV/AIDS drug development and treatment
- Liver Disease Diagnosis and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- HIV/AIDS Research and Interventions
- Congenital Heart Disease Studies
- Acute Myocardial Infarction Research
- Bariatric Surgery and Outcomes
- MicroRNA in disease regulation
- Vascular anomalies and interventions
- Diabetes Management and Research
- Cardiac pacing and defibrillation studies
- Case Reports on Hematomas
- Breast Implant and Reconstruction
China-Japan Friendship Hospital
2021-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2024
First Affiliated Hospital of Zhengzhou University
2023-2024
Sun Yat-sen University
2024
Peking Union Medical College Hospital
2022-2023
Peking University
2020-2023
Nanjing Medical University
2023
Jiangsu Province Hospital
2023
Peking University First Hospital
2020-2023
Beijing University of Chinese Medicine
2023
Abstract Background Stress hyperglycemia and glycemic variability (GV) can reflect dramatic increases acute fluctuations in blood glucose, which are associated with adverse cardiovascular events. This study aimed to explore whether the combined assessment of stress ratio (SHR) GV provides additional information for prognostic prediction patients coronary artery disease (CAD) hospitalized intensive care unit (ICU). Methods Patients diagnosed CAD from Medical Information Mart Intensive Care-IV...
Insulin resistance (IR) is involved in the pathophysiological processes of arrhythmias. Increasing evidence suggests triglyceride and glucose (TyG) index, metabolic score for insulin (METS-IR), glucose-body mass index (TyG-BMI), to high-density lipoprotein cholesterol (TG/HDL-C) ratio are simple reliable surrogates IR. Although they have been associated with atrial fibrillation (AF), supporting this limited. Here, first study investigate association between TyG-BMI AF recurrence following...
To study the dynamics of HIV drug resistance (HIVDR) and its association with virologic immunologic failure as well mortality among patients on combination antiretroviral therapy (cART) in China.We recruited 365 cART two rural Chinese counties 2003-2004 followed them every 6 months until May 2010.Virologic failure, HIVDR, death were documented. We used Kaplan-Meier proportional hazards models to identify timing events, risk factors for mortality.At end study, had been 1974.3 person-years, a...
HPTN 083 demonstrated that injectable cabotegravir (CAB) was superior to oral tenofovir disoproxil fumarate-emtricitabine (TDF-FTC) for HIV prevention in cisgender men and transgender women who have sex with men. We previously analyzed 58 infections the blinded phase of (16 CAB arm 42 TDF-FTC arm). This report describes 52 additional occurred up 1 year after study unblinding (18 34 Retrospective testing included testing, viral load quantification drug concentrations, resistance testing. The...
Background: Large epicardial adipose tissue (EAT) volume is associated with the incidence of premature ventricular beats. The relationship between EAT and idiopathic tachycardia (IVT) not yet clear. We aimed to investigate effect on risk IVT. Methods: This a retrospective consecutive case-control study from January 2020 September 2022. IVT patients (n=81) control (n=162) undergoing coronary computed tomography angiography (CCTA) were retrospectively recruited. in group all hospitalized for...
Aim Advanced liver fibrosis is independently associated with new onset of atrial fibrillation (AF). Non-invasive scores are considered an effective strategy for assessing fibrosis. This study aimed to investigate the association between advanced and AF recurrence after ablation in patients non-alcoholic fatty disease (NAFLD). Materials methods A total 345 NAFLD who underwent de novo 2019 2020 at two large hospitals China were included this study. was defined as occurrence arrhythmia more...
Abstract Introduction Individual variability of rivaroxaban was observed in clinical application. This study aimed to identify genetic variants associated with the pharmacodynamics and bleeding risk rivaroxbaban patients nonvalvular atrial fibrillation (NVAF). Materials Methods From June 2017, July 2019, this enrolled 257 NVAF receiving rivaroxaban. Pharmacodynamics assessed by determining anti‐Factor Xa (anti‐FXa) level 3 h after administration as peak concentration. Whole‐exome sequencing...
Purpose Cardiovascular magnetic resonance imaging exams can be performed during free‐breathing. This may especially important for boys with Duchenne muscular dystrophy (DMD) given their frequently limited breath‐hold abilities. The impact of the respiratory compensation method on quantitative measurements left ventricular (LV) rotational mechanics is incompletely understood. purpose this study was to evaluate differences in LV acquired breath‐holding (BH), free‐breathing averaging (AVG), and...
Background Index of cardiac electrophysiological balance (iCEB) has been widely used in clinical practice but no studies investigated the association between iCEB and prognosis general population. Objective To assess correlation Methods This retrospective cohort study involved adults aged 40–65 years who participated Third National Health Nutrition Examination Survey (NHANES-III) whose electrocardiograms were sinus rhythm. The corrected (iCEBc) was ratio QT interval (QTc) to QRS duration,...
Background The Age–D-dimer–Albumin (ADA), the CREDO-Kyoto, and PARIS scores have been established to predict thrombotic events. However, prognostic performance of these compared GRACE score in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) has not reported. Methods Consecutive AMI treated PCI were retrospectively enrolled at a teaching hospital China from January 2016 December 2019. primary endpoint was all-cause mortality secondary...
Background Epicardial adipose tissue (EAT) is related to atrial fibrillation. The association between EAT volume and premature ventricular complexes (PVCs) remains unclear. Our study aimed investigate the effect of on risk frequent PVCs burden levels PVCs. Methods This observational retrospectively recruited consecutive patients who had consultation 2019 2021 at First Affiliated Hospital Zhengzhou University. Frequent PVC ( n = 402) control undergoing non-contrast computed tomography (CT)...
Pulmonary vein stenosis (PVS) is a known complication after radiofrequency ablation of atrial fibrillation (RAAF) and often misdiagnosed owing to lack awareness regarding PVS among noncardiologists. Misdiagnosis results in unnecessary treatment; therefore, greater understanding can improve the management these patients.We report case 38-year-old man with history RAAF who presented massive hemoptysis. His symptoms persisted despite undergoing transcatheter bronchial artery embolization on two...
Background: The rivaroxaban dose regimen for patients with nonvalvular atrial fibrillation (NVAF) is complex in Asia. Given the high interindividual variability and risk of bleeding caused by Asians, influencing factors relationship between outlier biomarkers events need exploration. Methods: integrated pharmacokinetics (PK)/pharmacodynamics (PD) models were characterized based on rich PK/PD data from 304 healthy volunteers sparse PD [anti-factor Xa activity (anti-Xa) prothrombin (PT)] 223...
Background Apixaban is a superior direct oral anticoagulant exihibiting interindividual variability in concentration and response the real world. The present study aimed to identify genetic biomarkers associated with pharmacokinetics (PK) pharmacodynamics (PD) of apixaban healthy Chinese subjects.Methods This multicenter included 181 adults taking single dose 2.5 mg or 5 assessed their PK PD parameters. Genome-wide nucleotide polymorphism (SNP) genotyping was performed using Affymetrix Axiom...
Background: Epicardial adipose tissue (EAT) thickness is an independent predictor for the recurrence of premature ventricular beats after ablation. However, it unclear whether EAT volume associated with idiopathic tachycardia (IVT) following This study sought to investigate association between and IVT radiofrequency ablation patients. Methods: retrospective included 69 patients undergoing computed tomography examination before who underwent their first catheter 2017 2021. The predictive...
Inflammation plays a vital role in the occurrence and progression of atrial fibrillation (AF). The association between pericoronary adipose tissue attenuation (PCATA) AF recurrence following ablation has not been fully clarified.We aimed to evaluate PCATA after radiofrequency catheter (RFCA).Patients who underwent first RFCA for performed coronary computed tomography angiography before 2018 2021 were enrolled. predictive values investigated. area under curve (AUC), relative integrated...
Liver fibrosis scores have been demonstrated to be associated with poor prognosis after percutaneous coronary intervention (PCI). However, no studies compared the prognostic value of these in acute myocardial infarction (AMI) patients and without diabetes. We retrospectively enrolled 1576 AMI who underwent PCI. There were 177 all-cause deaths 111 cardiac during follow-up (median 3.8 years). The non-alcoholic fatty liver disease score (NFS) showed a better than fibrosis-8 (FIB-8) (Harrell’s...