A5002671654- Vibrio bacteria research studies
- Fungal Biology and Applications
- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Infective Endocarditis Diagnosis and Management
- Food Quality and Safety Studies
- Agriculture, Soil, Plant Science
- Streptococcal Infections and Treatments
- Ecology and Conservation Studies
- Impact of Light on Environment and Health
- Respiratory viral infections research
- Helicobacter pylori-related gastroenterology studies
- Mycorrhizal Fungi and Plant Interactions
- Mycobacterium research and diagnosis
- Acute Myeloid Leukemia Research
- Viral gastroenteritis research and epidemiology
- Antifungal resistance and susceptibility
- Antimicrobial Resistance in Staphylococcus
- Enterobacteriaceae and Cronobacter Research
- Chemical synthesis and alkaloids
- Hepatitis B Virus Studies
- Pneumonia and Respiratory Infections
- Cervical Cancer and HPV Research
- Tuberculosis Research and Epidemiology
Ewha Womans University
2015-2024
Ewha Womans University Medical Center
2010-2024
Chungnam National University
2009-2024
Sogang University
2014-2021
Kyung Hee University
2011-2020
Inje University Busan Paik Hospital
2019
Seoul National University
2013-2014
Gachon University
2014
Hankuk University of Foreign Studies
2006-2011
Korea Research Institute of Chemical Technology
2011
Cefoxitin-resistant Escherichia coli and Klebsiella pneumoniae are relatively prevalent in Korea, suggesting dissemination of plasmid-mediated AmpC beta-lactamases. In this study, 238 isolates cefoxitin-resistant E. K. (not including subspecies ozaenae rhinoscleromatis) were collected 2003 from 16 Korean hospitals. The prevalence beta-lactamases was determined by PCR. gene alleles detected bla(DHA-1), 10 (8.6%) 93 (76.2%); bla(CMY-1)-like, 14 (12.1%) 2 (1.6%); bla(CMY-2)-like, 38 (32.7%) 1...
Clostridium difficile (C. difficile) is a common causative agent of pseudomembranous colitis (PMC). C. difficile-associated diarrhea (CDAD) ranges from mild to life threatening PMC. Recently, highly virulent strain polymerase chain reaction ribotype 027 was found in North America, Europe, and Japan. A 52-yr-old woman with anti-tuberculosis medication neurogenic bladder due traffic accident experienced five episodes PMC after taking antibiotics for pneumonia along septic shock acute renal...
We evaluated the performance of Vitek MS for identification Gram-positive cocci routinely isolated in clinical microbiology laboratories. With a total 424 well-characterized isolates, results were compared to those conventional methods and 16S rRNA gene sequencing. The correctly identified 97.9 % isolates tested species level. 97.2 staphylococci (95.9 coagulase-negative staphylococci), 97.8 streptococci, 100 enterococci. For overall concordance rate between was 94.5 %. matrix-assisted laser...
The pathogenic bacterium Vibrio vulnificus exhibits the ability to form biofilm, for which initiation is dependent upon swimming motility by virtue of a polar flagellum. filament its flagellum composed multiple flagellin subunits, FlaA, -B, -C, and -D. In V. genomes, however, open reading frames (ORFs) annotated FlaE -F are also present. Although neither nor FlaF involved in formation cellular motility, they well expressed secreted extracellular milieu through secretion apparatus flagellar...
ABSTRACT The prevalence of furazolidone, nitrofurantoin, and metronidazole resistance among Helicobacter pylori strains was assessed with 431 clinical isolates. Fifty-two percent were resistant, compared to 2% (7 431) furazolidone nitrofurantoin. All seven furazolidone- nitrofurantoin-resistant isolates also resistant. rdxA , frxA fdxB knockouts did not result in or nitrofurantoin resistance. These data suggest that may be good alternatives for treating H. infection.
Vibrio vulnificus causes diseases through actions of various virulence factors, including the elastase encoded by vvpE gene. Through transposon mutagenesis V. vulnificus, expression was shown to be increased luxO mutation. Since gene is known positively regulated SmcR via direct binding promoter, role LuxO in smcR investigated. The luxAB-transcriptional fusions containing different lengths promoter region indicated that transcription negatively and a specific upstream required for this...
Several factors contribute to differences in Streptococcus pneumoniae serotype distribution. We investigated the distribution and antimicrobial resistance of S. isolated between 2014 2016 Korea.We collected a total 1,855 isolates from 44 hospitals May 2016, analyzed serotypes by sequential multiplex PCR. each patient age, source clinical specimen, pattern.The most common were 11A (10.1%), followed 19A (8.8%), 3 (8.5%), 34 (8.1%), 23A (7.3%), 35B (6.2%). The major invasive (12.6%), (7.8%),...
The aim of this study was to investigate the molecular mechanisms ertapenem resistance among Enterobacteriaceae isolates in a clinical microbiology laboratory at tertiary university hospital. A total 40 including 20 resistant and intermediate were collected from August 2012 July 2013. Ertapenem susceptibility confirmed by broth microdilution method. PCR sequencing analysis carbapenemase, AmpC β-lactamase, extended-spectrum β-lactamase (ESBL) genes performed. Outer membrane proteins (OMPs)...
The extracellular polysaccharides of Vibrio vulnificus play different roles during biofilm development. Among them, the effect lipopolysaccharide (LPS), which is crucial for bacterial adherence to surfaces initial stage formation, on formation process was examined using various types LPS extracts. Exogenously added strongly inhibited in a dose-dependent manner. In addition, exogenous addition deacylated form (dLPS) also formation. However, an fraction extracted from mutant not able produce...
Salmonella is one of the major causes food-borne infections. We investigated serotype distribution and antimicrobial resistance isolates collected in Korea between January 2016 December 2017. In total, 669 were from clinical specimens at 19 university hospitals. Serotyping was performed according to Kauffmann-White scheme, susceptibility tested using Sensititre EUVSEC plates or disk diffusion. Among strains, C (39.8%) B (36.6%) most prevalent serogroups. 51 serotypes identified, common S....
본 연구는 후지를 이용하여 다양한 건조방법에 의해 제조된 육포의 품질특성을 측정하여 가장 적합하고 안전하게 섭취할 수 있는 제조조건을 확립하기 위해 실시하였다. 대조구가 다른 처리구들에 비해 유의적으로 낮은 수분함량 및 수분활성도와 높은 TBA값을 나타내었다. 또한, 건조조건에 따른 색도를 비교한 결과, 명도(lightness)를 나타내는 <TEX>$L^*$</TEX>-값은 T1처리구가 T2처리구에 비하여 낮게 나타났으며, 적색도(redness)를 <TEX>$a^*$</TEX>-값은 처리구에 높게 나타났고, 황색도(yellowness)를 <TEX>$b^*$</TEX>-값은 T2처리구가 값을 보였다. 건조수율 측정 수율을 나타내어(p<0.05), 최종제품의 수율 측면에서는 T2처리구의 건조방법이 효과적인 건조방법으로 사료되었다. 각 물성측정 hardness, cohesiveness, gumminess, chewiness값과 springiness값을 나타내었으며(p<0.05),...
We evaluated the performance of various commercial assays for molecular detection human papillomavirus (HPV); recently developed AdvanSure HPV Screening real-time PCR assay (AdvanSure PCR) and Abbott RealTime High Risk (Abbott were compared with Hybrid Capture 2 DNA Test (HC2).All 3 tests performed on 177 samples, any sample that showed a discrepancy in was genotyped using INNO-LiPA genotyping and/or sequencing. On basis these results, we obtained consensus result, each test evaluated. also...
Background Multidrug-resistant Acinetobacter baumannii is an important causal pathogen of healthcare-associated infections, and colistin-resistant strains have recently emerged owing to the increased use colistin. Using next-generation sequencing (NGS), a single whole-genome (WGS) protocol can identify type pathogens, analyze genetic relationships among different predict pathogenic transmissions, detect antibiotic resistance genes. However, only few studies applied NGS in studying mechanism...
ABSTRACT EpsC, one of the components comprising type II secretion system (T2SS), was isolated from a human-pathogenic bacterium, Vibrio vulnificus , to evaluate its role in eliciting virulence. An espC -deleted mutant V. displayed reduced cytotoxicity human cell line HEp-2 and an attenuated virulence mouse model. This exhibited dramatic defects diverse extracellular proteins, such as outer membrane transporters, known secreted factors, notably, hemolysin (VvhA) elastase (VvpE). A defect...
The aim of this study was to investigate whether a water extract L. cladonioides (LC) has an anti-obesity effect in 3T3-L1 cells and obese mice. Treatment differentiated adipocytes with LC caused significant increase glycerol release reduced the protein expression adipogenic transcription factors, PPARγ C/EBPα. In animal model, mice were artificially induced by high fat diet for 10 weeks. Experimental groups treated (100 mg/kg/day) gavage next At end experiment, body weight group 14.2%...
Replacing glazing with polishing is still controversial in terms of the surface roughness dental porcelains. This study investigated performance a ceramic-polishing rubber wheel (CP-RW), which contains large uniform and rounded silicon carbide particles small diamond particles, improving two feldspathic porcelains for sintering CAD/CAM milling. Using confocal laser scanning microscopy, changes parameters were evaluated before after or three treatment groups: SofLex polishing, CP-RW Glazing....
This study was designed to develop machine-learning models predict COVID-19 mortality and identify its key features based on clinical characteristics laboratory tests. For this, deep-learning (DL) (ML) were developed using receiver operating characteristic (ROC) area under the curve (AUC) F1 score optimization of 87 parameters. Of two, DL model exhibited better performance (AUC 0.8721, accuracy 0.84, 0.76). However, we also blended with ML, ensemble performed best 0.8811, 0.85, 0.77). The is...
Coagulase-negative staphylococci (CoNS) are reported to be the leading cause of nosocomial bloodstream infections. Staphylococcus pettenkoferi is a novel member CoNS that was first isolated from human blood and bursitis wound in 2002. We have cases 6 S. strains specimens, including one pathogen 5 contaminants catheter colonizers. Brucker Biotyper (Brucker Daltonics, Bremen, Germany) molecular typing with 16S rRNA gene sequencing confirmed isolates as pettenkoferi. The conventional phenotypic...