- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Lipoproteins and Cardiovascular Health
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrhythmias and Treatments
- Infective Endocarditis Diagnosis and Management
- Oral microbiology and periodontitis research
- Cardiac Structural Anomalies and Repair
- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Aortic Disease and Treatment Approaches
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Temporomandibular Joint Disorders
- Advanced MRI Techniques and Applications
- Dental Erosion and Treatment
- Glioma Diagnosis and Treatment
- Congenital heart defects research
- Coronary Artery Anomalies
Hôpital Roger Salengro
2020-2022
University of Liège
2000-2022
Weatherford College
2021
Centre Hospitalier Universitaire de Lille
2020-2021
Centre Hospitalier Universitaire de Liège
2009-2018
Segeberger Kliniken
2015
EMO GVM Centro Cuore Columbus
2015
Guy's and St Thomas' NHS Foundation Trust
2015
Mayo Clinic
2013
Onze Lieve Vrouwziekenhuis Hospital
2009
Balloon-expandable coronary-artery stents were developed to prevent coronary restenosis after angioplasty. These devices hold vessels open at sites that have been dilated. However, it is unknown whether stenting improves long-term angiographic and clinical outcomes as compared with standard balloon
Background —Dual therapy with ticlopidine and aspirin has been shown to be as effective or more than conventional anticoagulation in patients an optimal result after implantation of intracoronary metallic stents. However, the safety efficacy antiplatelet alone unselected population not evaluated. Methods —Patients were randomized treatment alone. Indications for stenting classified elective (decided before procedure) unplanned (to salvage failed angioplasty optimize results balloon...
Valve thrombosis has yet to be fully evaluated after transcatheter aortic valve implantation. This study aimed report the prevalence, timing, and treatment of heart (THV) thrombosis.THV was defined as follows (1) THV dysfunction secondary diagnosed based on response anticoagulation therapy, imaging modality or histopathology findings, (2) mobile mass detected suspicious thrombus, irrespective in absence infection. Between January 2008 September 2013, 26 (0.61%) thromboses were reported out...
Transcatheter aortic valve implantation has become an alternative to surgery in higher risk patients with symptomatic stenosis. The aim of the ADVANCE study was evaluate outcomes following a self-expanding transcatheter system fully monitored, multi-centre 'real-world' patient population highly experienced centres.Patients severe stenosis at surgical whom CoreValve System decided by Heart Team were included. Endpoints composite major adverse cardiovascular and cerebrovascular events (MACCE;...
Cardiopoietic cells, produced through cardiogenic conditioning of patients' mesenchymal stem have shown preliminary efficacy. The Congestive Heart Failure Regenerative Therapy (CHART-1) trial aimed to validate cardiopoiesis-based biotherapy in a larger heart failure cohort.
Background Our aims were to compare coronary artery bypass grafting (CABG) and stenting for the treatment of diabetic patients with multivessel disease enrolled in Arterial Revascularization Therapy Study (ARTS) trial determine costs these 2 strategies. Methods Results Patients (n=1205) randomly assigned stent implantation (n=600; diabetic, 112) or CABG (n=605; 96). Costs per patient calculated as product each patient’s use resources corresponding unit costs. Baseline characteristics similar...
Background: Periodontitis has recently been identified as a potential risk factor for systemic pathologies such cardiovascular disease, the hypothesis being that periodontal pockets could release pro‐inflammatory bacterial components, instance endotoxins, into bloodstream. It is known oral cavity can be source of circulating bacteria, but this never shown and no evidence exists so far injury related to severity periodontitis. The aim present study was test influence gentle mastication on...
The primary results of Arterial Revascularization Therapy Study reported a greater need for repeated revascularization after percutaneous coronary intervention with stenting (PCI). However, PCI was less expensive than artery bypass grafting (CABG) and offered the same degree protection against death, stroke, myocardial infarction.Patients multivessel disease (n=1205) were randomly assigned to either CABG or followed up 3 years. Survival rates without stroke infarction similar in each group...
Background: There is increasing evidence that chronic infections, such as periodontal diseases, could play a role in the initiation and development of coronary artery disease (CAD). The present study was intended to test for possible association between presence severity periodontitis Belgian population. Methods: A total 108 CAD patients (mean age 59.2 ± 11 years) 62 presumably healthy controls 57.7 9 were enrolled study. Probing depth, pocket bleeding index (PPBI), plaque index, furcation...
Background— We assessed the safety and feasibility of permanent implantation a novel coronary sinus mitral repair device (PTMA, Viacor Inc). Methods Results— Symptomatic (New York Heart Association class 2 or 3) patients with primarily functional regurgitation (MR) were included. A diagnostic PTMA procedure was performed in venous continuity. MR adjusted to optimize efficacy. If reduction (≥1 grade) observed, placement implant attempted. Implanted evaluated echocardiographic, quality life,...
Abstract The aim of this multicenter pilot study was to evaluate the acute safety and efficacy dexamethasone‐eluting stent (0.5 μg/mm 2 stent) implanted in patients with de novo single‐vessel disease. This included 71 patients, 42% whom had unstable angina pectoris. An appropriately sized BiodivYsio Matrix Lo loaded a total dexamethasone dose 0.5 used. Technical device success rate 95%. Six‐month MACE occurred two (3.3%). Binary restenosis 13.3%. Late loss 0.45. percent diameter stenosis...
Aims: To determine whether there are gender-based differences in in-hospital outcomes among patients undergoing percutaneous coronary intervention (PCI). Methods and results:We studied a large cohort using clinical data from registry of 130,985 PCI procedures Belgium, January 2006 to February 2011.Compared males, females were significantly older (70.3 vs. 64.8years), more frequently diabetic or hypertensive.Men smoked had previous myocardial infarction (MI), artery bypass graft (CABG)...