A5086417219- Lung Cancer Diagnosis and Treatment
- Neuroscience of respiration and sleep
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Respiratory Support and Mechanisms
- Tracheal and airway disorders
- Dietary Effects on Health
- Diet and metabolism studies
- Bacterial biofilms and quorum sensing
- Cardiovascular and Diving-Related Complications
- Obstructive Sleep Apnea Research
- Occupational and environmental lung diseases
- Burkholderia infections and melioidosis
- Medical Imaging and Pathology Studies
- Inhalation and Respiratory Drug Delivery
- Pulmonary Hypertension Research and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Photodynamic Therapy Research Studies
- Bacterial Infections and Vaccines
- Diet, Metabolism, and Disease
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Biosensors and Analytical Detection
- Lymphatic System and Diseases
- Nutritional Studies and Diet
- Venous Thromboembolism Diagnosis and Management
Nanjing Medical University
2016-2023
Dongguan People’s Hospital
2023
Nanjing Jiangning Hospital
2020
Both low-carbohydrate (LC) and calorie-restricted (CR) diets have been shown to metabolic benefits. However, the two regimens yet be thoroughly compared. We conducted a 12-week randomized trial compare effects of these separately in combination on both weight loss risk factors overweight/obese individuals.
Obstructive sleep apnea syndrome (OSAS) is known to be a risk factor for atherosclerosis (AS), derived from series of chronic inflammatory reactions caused by hypoxia. However, the association between inflammation and high blood pressure hypoxia remains fully elucidated. The aim present study was investigate effect continuous positive airway (CPAP) therapy on cytokines AS. A total 100 patients with OSAS 50 healthy control subjects were enrolled. Fresh venous samples collected prior following...
Despite evidence of a relationship among obstructive sleep apnea (OSA), metabolic dysregulation, and diabetes, it is uncertain whether OSA treatment can improve parameters. We sought to determine effects long-term continuous positive airway pressure (CPAP) on glycemic control diabetes risk in patients with cardiovascular disease (CVD) OSA.Blood, medical history, personal data were collected substudy 888 participants the Sleep Apnea cardioVascular Endpoints (SAVE) trial which stable CVD...
Pseudomonas aeruginosa (P. aeruginosa) infections lead to a high mortality rate for cystic fibrosis or immunocompromised patients. The alginate of the biofilm was believed be key factor disabling immune therapy and antibiotic treatments. A silver nanocomposite consisting nanoparticles mesoporous organosilica layer created deliver two pharmaceutical compounds (alginate lyase ceftazidime) degrade eradicate P. from lungs. introduction thioether-bridged into nanocomposites greatly benefited...
Idiopathic pulmonary fibrosis (IPF) is a common interstitial disease with high mortality rate. Adiponectin (APN) reportedly an effective therapy for fibrosis-related diseases. This study aimed to investigate the potential effects of APN on IPF. Male BALB/c mice were injected bleomycin (BLM) and treated different doses (0.1, 0.25, 0.5 mg/kg). The body weights recorded. Immunohistochemical, hematoxylin eosin, Masson staining performed evaluate histopathological changes. Enzyme-linked...
While previous trials have indicated that the use of corticosteroids for patients with acute respiratory distress syndrome (ARDS) is effective, dosage and time-course remain a subject controversy. The present study aimed to address resolve these problems. PubMed, Embase Cochrane Library databases were searched from inception March 2017 randomized controlled (RCTs), which included ARDS using corticosteroids. Related data extracted independently by two investigators. Mantel-Haenszel method was...
Abstract Background: The aim of this study was to evaluate the diagnostic utility virtual bronchoscopic navigation (VBN) combined with endobronchial ultrasound (EBUS) guided transbronchial lung biopsy for solitary pulmonary nodules (SPN). Methods: A total 115 patients suspected SPN who underwent were evaluated. randomly divided into an EBUS group and a (VBN+EBUS) group. yield examination time compared. Results: There no significant difference in between VBN+EBUS (83.6% vs 66.7%, P = .419)....
Many recent studies have reported that autofluorescence bronchoscopy (AFB) has a superior sensitivity and decreased specificity in the diagnosis of bronchial cancers when compared with white-light (WLB). We specifically analyzed diagnostic performances imaging video (AFI) performed Evis Lucera Spectrum from Olympus, which is relatively novel approach detecting delineating cancers, it to older WLB method.We searched PubMed, Embase, Web Science, CNKI databases inception July 12th, 2018 for...
Objective: X-ray guided transbronchial ultrasound-guided lung biopsy (EBUS-TBLB) can improve the diagnostic yield of peripheral pulmonary lesions (PPLs), but it needs special requirements. The purpose this study was to investigate clinical value virtual bronchoscopy navigation (VBN) combined with EBUS-TBLB in diagnosis PPLs without guidance. Methods: 105 patients underwent or VBN randomly. yield, operation time and complications were evaluated 2 groups. Results: No significant difference...
Objective: This study aims to investigate whether there was a collaborative weight-loss effect or other metabolic benefits between low-carbohydrate (LCD) and calorie restriction (CR) on overweight/obese subjects from South China. Methods: We enrolled 290 overweight/overweight adults with similar dietary habits 13 hospitals in different areas of Participants were randomly assigned into four diets for 12-week intervention, including normal diet, calorie-restricted diet combined diet....
Pseudomonas aeruginosa (P. aeruginosa) infections present a grave threat to immunocompromised individuals, particularly those with cystic fibrosis due the development of bacterial biofilms. In this study, we engineered self-assembling chitosan-ceftazidime nanoparticles (CSCE) capable effectively penetrating biofilms and eradicating P. aeruginosa. The CSCE were synthesized through ionic cross-linking, combining negatively charged ceftazidime positively chitosan, resulting in uniform measuring...
This study aimed to evaluate the diagnostic and prognostic value of pleural effusion levels soluble receptor-binding cancer antigen expressed on SiSo cells (sRCAS1) in lung patients with malignant (MPE).Pleural samples were collected from 78 MPE, 48 benign (BPE). Pleural sRCAS1 concentrations measured by enzyme-linked immunosorbent assay.MPE has significantly higher than that BPE (P < .01). With a cutoff 18.7 U/mL, showed good performance for MPE. Univariate multivariate analysis indicated...