A5054431010- Migraine and Headache Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Valve Diseases and Treatments
- Cancer Immunotherapy and Biomarkers
- Vestibular and auditory disorders
- Glaucoma and retinal disorders
- Stroke Rehabilitation and Recovery
- Trigeminal Neuralgia and Treatments
- Neurological Disorders and Treatments
- Muscle activation and electromyography studies
- Parkinson's Disease Mechanisms and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Hemodynamic Monitoring and Therapy
- Cerebral Palsy and Movement Disorders
- Hemoglobin structure and function
- Cancer Genomics and Diagnostics
- Renal cell carcinoma treatment
- Intraocular Surgery and Lenses
- Hydrogen's biological and therapeutic effects
- Cardiac and Coronary Surgery Techniques
- Lung Cancer Treatments and Mutations
- EEG and Brain-Computer Interfaces
- Neonatal Respiratory Health Research
- Cardiac Structural Anomalies and Repair
- Intensive Care Unit Cognitive Disorders
University of Pavia
2021-2025
Imperial College London
2025
Università Cattolica del Sacro Cuore
1999-2024
Fondazione Istituto Neurologico Nazionale Casimiro Mondino
2021-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2024
Agostino Gemelli University Polyclinic
2017-2024
Urology Foundation
2024
Azienda USL di Bologna
2024
University of Parma
2016-2018
Princess Margaret Hospital for Children
2016
Rimegepant, a novel oral calcitonin gene-related peptide receptor antagonist, has been recently approved for the acute migraine treatment. While its efficacy was confirmed in randomized clinical trials, no data is available regarding real-life effectiveness and tolerability. GAINER, prospective, multicentric study, aimed to evaluate rimegepant tolerability real-world setting. Our study involved 16 headache centers across Italy. The main outcomes were: i) 2 h pain freedom, ii) occurrence of...
This study introduces a novel paradigm to induce the torsional vestibulo‐ocular reflex (VOR) using head circumduction ‐ circular motion of combining extension, lateral rotation and flexion neck. The aims were (i) evaluate reliability this manoeuvre in generating nystagmus (ii) explore impact post‐rotational tilt on induced VOR responses. Fourteen healthy participants (age = 27.3±5.3 years) tested 3D eye‐tracker record eye movements by circumduction, performed at frequency 0.75 Hz....
miR-155 is involved in the generation and maintenance of inflammation pain, endothelial function immune system homeostasis, all functions that are relevant for migraine. The present study aims to assess levels migraine subtypes (episodic chronic) comparison age- sex-matched healthy controls.
Abstract Background In Italy, monoclonal antibodies targeting the CGRP pathway are subsidized for preventive treatment of high frequency and chronic migraine (CM) in patients with a MIgraine Disability ASsessment (MIDAS) score ≥ 11. Eligibility to continuation requires 50% MIDAS reduction at three months (T3). this study, we evaluate whether T3 is reliable predictor response one-year erenumab treatment. Methods prospective, open-label, real-world 77 CM were treated 70–140 mg s.c. every 28...
The objective of this paper is to present the development and use a numerical model predict noise radiated from manual gearboxes due gear rattle using Computer-Aided Engineering (CAE) technologies. This CAE process, as outlined in paper, includes measured data, computational flexible multibody dynamics, vibro-acoustic analysis. data used identify reproduce input excitation which primarily generated engine combustion forces. dynamic interaction gearbox components, including flywheel,...
Abstract Stroke affects the interconnection between nervous and immune systems, leading to a down-regulation of immunity called stroke-induced immunosuppression (SII). The primary aim this study is investigate SII role as predictor functional, neurological, motor outcomes in neurorehabilitation setting (NRB). We conducted prospective observational enrolling post-acute stroke patients hospitalized for neurorehabilitation. At NRB admission (T 0 ) discharge 1 ), we assessed presence (defined by...
Preliminary but convergent findings suggest a role for microRNAs (miRNAs) in the generation and maintenance of chronic pain migraine. Initial observations showed that serum levels miR-382-5p miR-34a-5p expression were increased during migraine attack, with increasing interictal phase as well. By contrast, miR-30a-5p lower patients compared to healthy controls. Of note, antimigraine treatments proved be capable influencing these miRNAs. Altogether, miRNAs may represent biomarkers, several...
The partial pressure of carbon dioxide (pCO2) gap is the difference between pCO2 values in arterial and mixed venous blood; higher than six mmHg may be predictive tissue hypoperfusion. It still doubtful if central blood can used to assess gap. This study was aimed compare obtained with collected from superior vena cava pulmonary artery.Data were a previous study. In 30 patients who underwent on-pump myocardial revascularization, samples radial artery, eight times perioperative period....
Background: The sequence effect (SE), defined as a reduction in amplitude of repetitive movements, is common clinical feature Parkinson's disease (PD) and supposed to be major contributor freezing gait (FOG). During walking, SE manifests step-by-step step length when approaching turning point or destination, resulting the so-called destination (dSE). Previous studies explored therapeutic effects several strategies on SE, but none them evaluated role an intensive rehabilitative program....
Dynamic obstruction of right ventricle outflow tract (RVOTO) is a rare condition that may acutely cause severe heart failure. It has been reported in some hypertrophic cardiomyopathies, after lung transplantation, and cases hemodynamic instability cardiopulmonary bypass. We report the case 71-year-old man who developed hypotension during induction general anesthesia for surgical coronary revascularization. Hypotension did not respond to initial treatment with vasoconstrictors fluids. RVOTO...
Introduction: Habituation is a physiological phenomenon, characterized by response reduction to repeated stimulus presentation. In headache disorders, habituation studies have involved different paradigms with several stimulation parameters and sensory modalities, consistently showed impaired in primary headaches the interictal phase. The nociceptive blink reflex (nBR) its related R2 response, modulated polysynaptic network trigeminocervical complex, one of most studied field. lack nBR...