- Thyroid Cancer Diagnosis and Treatment
- Cholinesterase and Neurodegenerative Diseases
- Biological Activity of Diterpenoids and Biflavonoids
- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
- Natural product bioactivities and synthesis
- Phosphodiesterase function and regulation
- Alzheimer's disease research and treatments
- Parathyroid Disorders and Treatments
- Biomarkers in Disease Mechanisms
- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Adenosine and Purinergic Signaling
- Neuroinflammation and Neurodegeneration Mechanisms
- Plant-derived Lignans Synthesis and Bioactivity
- Inflammation biomarkers and pathways
- Free Radicals and Antioxidants
- Comparative Animal Anatomy Studies
- Proteoglycans and glycosaminoglycans research
- Traditional Chinese Medicine Analysis
- Phytochemistry and Biological Activities
- Esophageal Cancer Research and Treatment
- Cancer Diagnosis and Treatment
- NF-κB Signaling Pathways
- Phytochemical Studies and Bioactivities
Zunyi Medical University
2014-2024
Guizhou University
2024
Affiliated Hospital of Guizhou Medical University
2024
Lishui Central Hospital
2017-2023
Wenzhou Medical University
2020-2023
Weatherford College
2021
Lishui University
2020-2021
Shenyang Pharmaceutical University
2014-2020
Zhejiang University
2020
Chinese People's Armed Police Force
2019
Objectives To evaluate the diagnostic performance of real-time elastography (RTE) combined with fine-needle aspiration (FNA) biopsy in identifying malignant thyroid nodules. Methods This was a single-centre, retrospective study and involved patients who had underogone partial or total thyroidectomy from 01 January 2014 to 31 December 2018 at our centre. Eligible were least18 years age, reliable grayscale ultrasound imaging results, RTE evaluation undergone FNA biopsy. Results Data available...
Objective . To identify the clinicopathological features correlated to lymph node metastasis (LNM) in patients with papillary thyroid microcarcinoma (PTMC). Methods Clinical data of 785 PTMC who underwent surgical treatment at Lishui Municipal Central Hospital from September 2008 December 2017 were retrospectively analyzed. and pathological risk factors for (LNM), central (CLNM), lateral (LLNM) Results LNM was found 236 (30.2%) patients. Multivariate logistic regression analysis revealed...
The dried roots of the plant Acanthopanax senticosus (AS) are used in traditional Oriental medicine and reportedly possess anti-inflammatory properties vitro.However, whether AS has same effect vivo underlying mechanisms this action remain unknown.In study, we pretreated a mouse model lipopolysaccharide-induced acute lung injury with found that levels tumor necrosis factor (TNF)-α, interleukin ©FUNPEC-RP www.funpecrp.com.brGenetics Molecular Research 13 (4): 10537-10544 (2014) X.J. Fei et...
In this paper, an efficient approach to extract total flavonoids (TFs) from Selaginella involvens (Sw.) Spring using homogenate-ultrasound-assisted ionic liquid (IL) extraction (HUA-ILE) was first developed. The results indicated that EPyBF4 selected as the suitable extractant. According single factor experiment and response surface methodology, IL concentration of 0.10 mol/L, time 160 s, liquid/solid ratio 13:1 mL/g, power 300 W were concluded best conditions. A yield 8.48 ± 0.27 mg/g TF...
Drug-refractory secondary hyperparathyroidism (SHPT) is the most common complication in patients with chronic renal failure (CRF). Although surgery effective and safe method for drug-refractory SHPT, condition may persist or recur after primary surgery, reoperation often required these patients. The purpose of our current study was to evaluate safety effectiveness SHPT.The clinical data 15 requiring a SHPT hospital from 2010 2019 were retrospectively analyzed. Changes biochemical markers...
Our study aims to test the diagnostic performance of contrast-enhanced ultrasound (CEUS) combined with detection serine/threonine-protein kinase V600E (BRAF V600E) in nodules unclear significance by thyroid fine-needle aspiration (FNA).From January 2015 December 2019, 244 patients were subjected ultrasonic strain imaging and elastography, CEUS, BRAF gene at Lishui Hospital Zhejiang University. Thyroid FNA does not confirm benignancy malignancy nodules. With postoperative pathology as gold...
Background: To investigate the correlation of thyroglobulin antibody (TgAb) and thyroid peroxidase (TPOAb) with risk papillary carcinoma (PTC). Methods: The clinical data 322 patients pathologically confirmed nodules who underwent surgical treatment in Lishui Hospital Zhejiang University from January 2018 to December 2019 were enrolled this study. divided into a benign nodule group PTC according their pathological results. Comparison was drawn based around difference autoantibody...
Abstract In the study, four main biflavonoids (bilobetin (BIL), ginkgetin (GIN), isoginkgetin (IGIN) and sciadopitysin (SCI)) were extracted from Ginkgo biloba L . by ultrasonic‐assisted ionic liquid extraction (UAILE). The above simultaneously determined established high performance chromatography (HPLC) approach. Next, three novel liquids (ILs) synthesized one‐step method benzoxazole acids or salts. structure of ILs characterized elemental analysis, infrared spectroscopy nuclear magnetic...
Background The risk factors for hypoparathyroidism after thyroid surgery have not been fully identified. This study analyzes the of before and total thyroidectomy. Methods We retrospectively collected clinical data 289 patients who underwent thyroidectomy at Thyroid Surgery Center Lishui Central Hospital from June 2018 to 2020. For anatomy protection parathyroid glands during operation, one group used avoidance method, other active exploration method. Various affecting dysfunction were...
The purpose of this retrospective study was to explore the primary possible risk factors for development postoperative hyperkalemia after total parathyroidectomy with autotransplantation (TPTX + AT) in patients drug-refractory secondary hyperparathyroidism (SHPT).The clinical data 149 receiving maintenance dialysis SHPT, who underwent TPTX AT, were reviewed and analyzed. Demographic data, status, laboratory test indices collected from enrolled patients. According serum potassium level >5.3...
Abstract Background : Emodin has been shown to exert anti‐inflammatory and cytoprotective effects. Our study aimed identify a novel mechanism of emodin. Methods An LPS‐induced model microvascular endothelial cell (HMEC‐1) injury was constructed. Cell proliferation examined using CCK‐8 assay. The effects emodin on reactive oxygen species (ROS), migration, the mitochondrial membrane potential (MMP), opening permeability transition pore (mPTP) were evaluated. Actin‐Tracker Green used examine...
Abstract Objectives To determine whether ecto-5′-nucleotidase (e5NT) contributes to the release of adenosine and uridine is establishes role e5NT in acute restraint stress-induced depression anxiety-like behaviours mice. Methods Acute stress was induced detect level nucleoside hippocampus. Mouse hippocampal brain proteins were isolated subjected Western blotting (WB) experiments examine protein expression levels that affect release. Adenosine 5′-(α,β-methylene)diphosphate (APCP), an...
To study the changes of soluble Apo-1/Fas levels in plasma, pleural and ascites fluid malignant tumor patients to evaluate their clinical significance.The were measured by enzyme-linked immunosorbent assay (ELISA) plasma 157 25 normal controls as well ascite fluids 129 with various diseases.The acute chronic leukemia multiple myeloma significantly higher than those (P <0.05). The myeloid lymphocytic leukemia, respectively After chemotherapy, complete remission group distinctly decreased(P...