A5084199076- Salmonella and Campylobacter epidemiology
- Vibrio bacteria research studies
- Streptococcal Infections and Treatments
- Antibiotic Resistance in Bacteria
- Escherichia coli research studies
- Bacteriophages and microbial interactions
- Clostridium difficile and Clostridium perfringens research
- Acne and Rosacea Treatments and Effects
- Biochemical and Structural Characterization
- Pediatric health and respiratory diseases
- SARS-CoV-2 and COVID-19 Research
- Child Nutrition and Water Access
- Legume Nitrogen Fixing Symbiosis
- Bacterial Identification and Susceptibility Testing
- IL-33, ST2, and ILC Pathways
- Antibiotic Use and Resistance
- Plant Stress Responses and Tolerance
- Immune responses and vaccinations
- Amoebic Infections and Treatments
- Plant-Microbe Interactions and Immunity
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Bacterial Genetics and Biotechnology
- Inflammation biomarkers and pathways
- Immune Cell Function and Interaction
University of Utah
2020-2023
University of Nebraska Medical Center
2022-2023
New York Proton Center
2023
Communities In Schools of Orange County
2023
Manhattan Institute for Policy Research
2023
Oregon Medical Research Center
2023
Lindsay Unified School District
2023
University of Wisconsin–Madison
2018-2021
Bacterial cell division involves the dynamic assembly of proteins and coordinated constriction envelope. A wide range factors regulates division--including growth environmental stresses--and targeting machinery has been a widely discussed approach for antimicrobial therapies. This paper introduces divin, small molecule inhibitor bacterial that may facilitate mechanistic studies this process. Divin disrupts late proteins, reduces peptidoglycan remodeling at site, blocks compartmentalization...
Salmonellosis outbreaks associated with sprouted legumes have been a food safety concern for over two decades. Despite evidence that Salmonella enterica triggers biotic plant defense pathways, it has remained unclear how defenses impact growth on legumes. We used Medicago truncatula mutants in which the gene flagellin receptor FLS2 was disrupted to demonstrate triggered by elicitation do not of serovar Typhimurium ATCC 14028S. As control, we tested LT2, defect rpoS increases its sensitivity...
Abstract Background Disseminated Clostridium septicum infection is an uncommon complication associated with malignancies, particular colonic adenocarcinoma. The organism appears to preferentially colonize large masses in rare individuals and subsequently seed the blood via mucosal ulceration. This has rarely been reported lead central nervous system and, several cases, rapidly progressive pneumocephalus. In few cases reported, this was a universally fatal condition. current case adds reports...
Abstract Background Enterohemorrhagic Escherichia coli O157:H7 (EHEC) is a significant foodborne pathogen that resides asymptomatically within cattle and other ruminants. The EHEC genome harbors an extensive collection of mobile genetic elements (MGE), including multiple prophage, prophage-like elements, plasmids, insertion sequence (IS) elements. Results A chronological strains (FRIK804, FRIK1275, FRIK1625) isolated from Wisconsin dairy farm (farm X) comprised closely related clade...
Pneumonia and diarrhea are among the leading causes of death worldwide, epidemiological studies have demonstrated that is associated with an increased risk subsequent pneumonia. Our aim was to determine impact intestinal infection on innate immune responses in lung. Using a mouse model by Salmonella enterica serovar Typhimurium (S. [ST]), we investigated associations between gastrointestinal infections lung bacterial (Klebsiella pneumoniae) challenge. We found alterations frequencies cells...
The outer membrane of Salmonella enterica plays an important role in combating stress encountered the environment and hosts. transport insertion lipopolysaccharides (LPS) into involves lipopolysaccharide proteins (LptA-F) mutations genes encoding for these are often lethal or result atypical LPS that can alter tolerance bacteria. During studies heterogeneity bile salts tolerance, S. serovar Typhimurium E40 was segregated tolerant sensitive cells by screening growth TSB with 10% salts. An...
Background: Cutibacterium acnes is a common commensal of human skin but may also present as an opportunistic pathogen in prosthetic joint and wound infections. Unfortunately, few complete genomes C. are publicly available, even fewer isolates associated with infection. Here we report the isolation, characterization, 2 from surgical site infection elbow. Methods: We used standard microbiological methods for phenotypic characterization performed whole genome sequencing on using combination...
Abstract Background Pneumonia and diarrhea are among the leading causes of death worldwide, epidemiological studies have demonstrated that is associated with an increased risk subsequent pneumonia. Our aim was to determine impact intestinal infection on innate immune responses in lung. Methods Using a mouse model by Salmonella enterica serovar Typhimurium ( S . ST )), we investigated how gut compartment can modulate immunity lungs susceptibility bacterial Klebsiella pneumoniae KP ))...
In September 2021, a cluster of 6 patients with nosocomial coronavirus disease 2019 (COVID-19) were identified in transplant unit. A visitor and 11 healthcare workers also tested positive for severe acute respiratory virus 2 (SARS-CoV-2). Genomic sequencing 3 separate introductions SARS-CoV-2 related transmission among the workers.
Cholera remains a significant public health burden worldwide, and better methods for monitoring cholera incidence would enhance the effectiveness of interventions. The serum bactericidal assay (SBA) has been used extensively Vibrio cholerae vaccine assessments serosurveillance. Current SBA approaches V. rely on colony enumeration or optical density (OD600nm) readings to measure viable bacteria following complement-mediated lysis. These provide titer values that are constrained discrete...