A5102743004- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Simulation and Modeling Applications
- Advanced Neuroimaging Techniques and Applications
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Advanced MRI Techniques and Applications
- Immune cells in cancer
- Peripheral Nerve Disorders
- Cancer Immunotherapy and Biomarkers
- Pain Mechanisms and Treatments
- Metabolism, Diabetes, and Cancer
- Sarcoma Diagnosis and Treatment
- Fetal and Pediatric Neurological Disorders
- Educational Technology and Assessment
- Sleep and Wakefulness Research
- Epigenetics and DNA Methylation
- Infrastructure Maintenance and Monitoring
- Liver Disease Diagnosis and Treatment
- RNA modifications and cancer
- Antibiotics Pharmacokinetics and Efficacy
- Chronic Kidney Disease and Diabetes
- Cerebral Palsy and Movement Disorders
- Neuroscience of respiration and sleep
Air Force Medical University
2024
Harbin Huade University
2023-2024
Bengbu Medical College
2016-2024
First Affiliated Hospital of Guangzhou Medical University
2021-2023
Guangzhou Medical University
2021-2023
Huizhou Central People's Hospital
2010-2021
Chongqing Dazu District People's Hospital
2013
Objective To evaluate the performance of 2D and 3D radiomics features with different machine learning approaches to classify SPLs based on magnetic resonance(MR) T2 weighted imaging (T2WI). Material Methods A total 132 patients pathologically confirmed were examined randomly divided into training (n = 92) test datasets 40). 1692 1231 per patient extracted. Both clinical data evaluated. 1260 classification models, comprising 3 normalization methods, 2 dimension reduction algorithms, feature...
Objective:: Ulcerative colitis (UC) is a chronic non-specific inflammatory disease of the rectum and colon with unknown etiology. A growing number evidence suggest that pathogenesis UC related to excessive apoptosis production cytokines. However, functions molecular mechanisms associated remain unclear. Materials Methods: The in vivo vitro models were established this study. MiRNA or gene expression was measured by qRT-PCR assay. ELISA, CCK-8, TUNEL, flow cytometry assays applied for...
Abstract Objective This clinical study was designed to evaluate the efficacy and safety of this therapy in treatment respiratory urinary infections caused by ceftriaxone-resistant bacteria comparison with effect cefoperazone/sulbactam on cefoperazone-resistant bacteria. Methods A total 285 patients aged from 18 65 years old, a or tract bacterial infection, were enrolled into multicentre, open-label, controlled study, that either isolated patients, whose condition had not improved after three...
The epidermal growth factor receptor (EGFR) is an important therapeutic target for patients with non-small-cell lung cancer (NSCLC). Radiomics and radiogenomics have emerged as attractive research topics aiming to extract mineable high-dimensional features from medical images show potential correlate the gene mutation. Herein, we aim develop a magnetic resonance imaging (MRI)-based radiomics model pretreatment prediction of EGFR status in adenocarcinoma.A total 92 pathologically confirmed...
Objective To develop and validate radiomics models based on multiphasic CT in predicting Kirsten rat sarcoma virus (KRAS) gene mutation status patients with colorectal cancer (CRC). Materials Methods A total of 231 pathologically confirmed CRC were retrospectively enrolled randomly divided into training(n=184) test groups(n=47) a ratio 4:1. 1316 quantitative features extracted from non-contrast phase (NCP), arterial-phase (AP) venous-phase (VP) for each patient. Four steps applied feature...
Objective. Free triiodothyronine (FT3) is an independent risk factor for nonalcoholic fatty liver disease (NAFLD) in patients with euthyroid. However, whether FT3 has effect on NAFLD a population of type 2 diabetes remains unknown. The purpose this study was to identify the potential role T2DM. Design. A cross-sectional study. Patient. total 859 T2DM who met inclusion criteria were included. There 506 without and 353 NAFLD. Methods. samples <math xmlns="http://www.w3.org/1998/Math/MathML"...
Background The treatment efficacy of angiogenesis inhibitor could be underestimated at an early stage based on tumor volume changes. Intravoxel incoherent motion diffusion‐weighted imaging (IVIM‐DWI) can quantitatively assess tumors the cellular level, but it is unclear whether provide useful information for assessing response anti‐angiogenic lung adenocarcinoma. Purpose To determine use IVIM‐DWI non‐invasive monitoring to in orthotopic transplantation adenocarcinoma model. Study Type...
Motivation: Early symptoms of obesity-related glomerulopathy (ORG) are atypical and diagnosis depends on invasive kidney biopsy. Goal(s): This study assessed the potential intravoxel incoherent motion (IVIM) to detect renal injury induced by ORG monitor function after weight loss therapy. Approach: IVIM were performed in high fat diet (HF) standard (St) rats&rsquo; before Results: Compared with St group, significant decreases D, D*, f HF group observed, D was first decrease. After...
In the current study, we assessed possible alterations of brain white matter (WM) microstructure in patients with obstructive sleep apnea (OSA) using generalized q-sampling imaging (GQI). We found higher normalized quantitative anisotropy values bilateral superior longitudinal fasciculus, uncinate fornix, and corpus callosum bundle OSA group vs controls, which were related to multiple clinical indices OSA.
In the current study, we assessed possible alterations of iron accumulation in brain patients with Obstructive Sleep Apnea (OSA) using quantitative susceptibility mapping (QSM). We found that there was increased bilateral hippocampus for OSA, compared to controls. And QSM value related course disease OSA. The values right were correlated multiple clinical indicators and may therefore be used as potential biomarkers further understand pathophysiological mechanisms moderate severe