A5101818805- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Antibiotic Resistance in Bacteria
- Scoliosis diagnosis and treatment
- Vibrio bacteria research studies
- Bacterial biofilms and quorum sensing
- Infections and bacterial resistance
- Aquaculture disease management and microbiota
- Genomics and Phylogenetic Studies
- Musculoskeletal pain and rehabilitation
- Cervical and Thoracic Myelopathy
- Protist diversity and phylogeny
- Inflammasome and immune disorders
- Infectious Disease Case Reports and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Pharmaceutical and Antibiotic Environmental Impacts
- Neurosurgical Procedures and Complications
- Pregnancy-related medical research
- Cerebrospinal fluid and hydrocephalus
- Identification and Quantification in Food
- IL-33, ST2, and ILC Pathways
- Head and Neck Surgical Oncology
- Malaria Research and Control
- Effects of Vibration on Health
- Spinal Hematomas and Complications
National Institute for Communicable Disease Control and Prevention
2020-2024
The Third Affiliated Hospital of Zhejiang Chinese Medical University
2024
Chinese Center For Disease Control and Prevention
2020-2023
State Key Laboratory of Infectious Disease Prevention and Control
2020-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2008-2022
Peking Union Medical College Hospital
2008-2022
Introduction Stenotrophomonas maltophilia complex (Smc) comprises opportunistic Gram-negative bacilli responsible for various nosocomial infections. Limited data exists concerning its evolutionary lineage, global prevalence and pathogenicity. Methods We conducted an extensive genomic analysis on 734 Smc genomes, of which 90 were newly sequenced isolated from different patients. The species composition relationships examined using core protein sequence analysis. Pathogenicity evaluation was...
Extended-spectrum β-lactamases (ESBLs) producing bacteria have spread worldwide and become a global public health concern. Plasmid-mediated transfer of ESBLs is an important route for resistance acquisition.
Shewanella algae is widely distributed in marine and freshwater habitats, has been proved to be an emerging zoonotic human pathogen. However, the genomic characteristics pathogenicity of are unclear. Here, whole-genome features 55 S . strains isolated from different sources were described. Pan-genome analysis yielded 2863 (19.4 %) genes shared among all strains. Functional annotation core genome showed that main functions focused on basic lifestyle such as metabolism energy production....
Rhodococcus equi is a zoonotic pathogen that can cause fatal disease in patients who are immunocompromised. At present, the epidemiology and pathogenic mechanisms of R. infection not clear. This study characterized genomes 53 strains from different sources. Pan-genome analysis showed all contained 11481 pan genes, including 3690 core genes 602 ~ 1079 accessory genes. Functional annotation genome focused on related to basic lifestyle, such as storage expression metabolic genetic information....
The genus Vibrio is ubiquitous in marine environments and uses numerous evolutionary characteristics survival strategies order to occupy its niche. Here, a newly identified species, fujianensis, was deeply explored reveal unique environmental adaptability. V. fujianensis type strain FJ201301T shared 817 core genes with the species population genomic analysis, but possessed of own. In addition, predicated carry 106 virulence-related factors, several which were mostly found other pathogenic...
Objective After percutaneous endoscopic lumbar discectomy (PELD), most patients with disc herniation (LDH) experience relief from the typical symptoms of low back and leg pain. However, for a small number patients, these are relieved immediately after surgery but aggravated soon after, then short‐term full rest or conservative treatment. The aim study was to demonstrate this recurrent phenomenon, termed rebound Methods A retrospective conducted on 144 who underwent single‐segment PELD May...
Minimally invasive lumbar spine fusion surgery has gained popularity in recent years. Routinely, this technique requires bilateral parasagittal incisions for decompression, interbody fusion, and posterior instrumentation. The following study is a description of new minimally one-level transforaminal (TLIF) using unilateral incision (Wiltse approach), with placement pedicle screws then percutaneous transpedicular facet screw insertion on the contralateral side. biomechanical stability...
Retrospective characterization of nonspecific low back pain (NSLBP) in young adult female patients with and without lumbar scoliosis.There is no consensus as to whether NSLBP scoliosis related per se or just a normal symptom that could happen anyone.The aim this study was compare the differences between provide theoretical basis for differential treatment scoliosis.Ninety adults were divided into nonscoliosis groups. Characteristics pain, mobility, muscle strength, Cobb angle, axial trunk...
A combined retrospective and prospective analysis on the therapeutic effect of physiotherapeutic scoliosis-specific exercise (PSSE) in mild juvenile idiopathic scoliosis (JIS) patients.At present, patients with JIS are generally treated by observation without any interventional treatment. This study analyzed effects PSSE JIS, which provided a new approach for treatment JIS.A total 52 (Cobb angle 10-19°), aged 4-9 years, self-selected into an group group. Patients performed corrective posture...
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Introduction The horizontal transfer of antibiotic resistance genes mediated by plasmids seriously hinders the effectiveness modern medical treatment, and thus has attracted widespread attention. Additionally, co-selection mechanism (ARGs) heavy metal (MRGs) on mobile elements may further exacerbate genes. Methods In this study, a multidrug-resistant Pseudomonas aeruginosa strain, termed BJ86 (CHPC/NPRC1.4142), was isolated from patient's sputum specimen. vitro tests for antimicrobial...
Polymyxins are the last line of defense in infections caused by multidrug-resistant Gram-negative bacteria. The chromosomal EptA Aeromonas genus was defined as a nonmobile colistin resistance determinant 3 (NMCR-3). A total 14 NMCR-3 genotypes were identified. global prevalence Aeromonas-borne NMCRs and MCRs indicates an increasing trend from 1968 to 2022. And index risk, i.e, ratio η = MCR/NMCR, proposed evaluate propagation potential NMCR-3. North America Europe faced high risk incidence...
The current unilateral biportal endoscopy (UBE) technique was originated from Argentina and developed in South Korea, which rapidly growing popularizing China. adoption of spinal endoscopy, using small cameras placed inside body with continuous water irrigation, providing better surgical field less tissue dissection quicker recovery for patients. As other disciplines, the use surgery will become increasingly widespread. UBE promote popularization China monoportal technique. At same time, has...