A5088980297- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Vasculitis and related conditions
- Neurological Complications and Syndromes
- Cardiac Arrhythmias and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Streptococcal Infections and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Bacterial Infections and Vaccines
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological disorders and treatments
- Clinical practice guidelines implementation
- Otitis Media and Relapsing Polychondritis
- Neonatal and Maternal Infections
- Long-Term Effects of COVID-19
- Cerebral Venous Sinus Thrombosis
- Otolaryngology and Infectious Diseases
- Parkinson's Disease Mechanisms and Treatments
- Abdominal Surgery and Complications
- Cerebrovascular and genetic disorders
- COVID-19 Clinical Research Studies
Hospital Universitario Rey Juan Carlos
2017-2024
Bayer (Germany)
2024
Boston Medical Center
2022
Boston University
2022
Universidad Rey Juan Carlos
2020
Hospital Universitario Ramón y Cajal
2011-2017
Instituto Ramón y Cajal de Investigación Sanitaria
2011-2016
Instituto Cajal
2014
Universidad de Alcalá
2012
Background and purpose: Therapy for stroke with intravenous tissue plasminogen activator (IV‐tPA) is hampered by tight licensing restrictions; some of them have been discussed in recent literature. We assessed the safety effectiveness off‐label IV‐tPA clinical settings. Methods: Retrospective analysis all patients treated at our Stroke Unit. Patients were divided into two groups licence criteria [on‐label group (OnLG), (OffLG)]. Primary outcome measures symptomatic intracranial haemorrhages...
<b><i>Background:</i></b> Patients who present with symptoms mimicking ischaemic stroke (IS), but have a different diagnosis, are known as mimics (SM). The necessity for rapid administration of intravenous thrombolysis in patients acute IS may lead to treatment conditions stroke. A variable proportion SM (1.4–14%) currently treated tissue plasminogen activator therapy (IV-tPA). outcome these is generally favourable and complications rather infrequent. We aimed...
The minimum basic dataset is the largest available hospital care administrative database that used in clinical studies and management association with diagnosis-related groups (DRGs). In 2011, quality of national MBDS discharges was audited, order to assess its reliability. This paper presents a sub-analysis results from analysis which are referred cerebrovascular disease (CVD).Using all discharge reports Spanish 2009, representative sample obtained by stratified sampling 11 209 records were...
Background and purpose The syndrome of transient headache neurological deficits with cerebrospinal fluid lymphocytosis (Ha NDL ) can present as sudden onset focal which are clinically radiologically indistinguishable from an ischaemic stroke. Its diagnosis requires a lumbar puncture ( LP ), contraindicates intravenous thrombolytic therapy IV ‐ tPA ). Methods All patients referred to our stroke centre code resulting in final Ha June 2005 2015 were retrospectively analysed. Results Nine cases...
Hyperechogenicity of the substantia nigra on transcranial sonography is used for diagnosing Parkinson disease (PD). Cutoff values echogenic area, defining hyperechogenicity, vary among ultrasound systems from different manufacturers. In this study we wanted to determine cutoff criterion a Toshiba (Tokyo, Japan) system and assess its diagnostic value.Three hundred participants (controls, n = 138; patients with PD, 105; essential tremor, 57) underwent following standardized protocol.The was...
The minimum basic dataset is the largest available hospital care administrative database that used in clinical studies and management association with diagnosis-related groups (DRGs). In 2011, quality of national MBDS discharges was audited, order to assess its reliability. This paper presents a sub-analysis results from analysis which are referred cerebrovascular disease (CVD). Using all discharge reports Spanish 2009, representative sample obtained by stratified sampling 11 209 records...
For patients with acute ischaemic stroke due to large-vessel occlusion, it has recently been shown that mechanical thrombectomy (MT) stent retrievers is better than medical treatment alone. However, few hospitals can provide MT 24 h/day 365 days/year, and remains unclear whether selected should be directly transferred the nearest MT-providing hospital prevent delays. Clinical scales such as Rapid Arterial Occlusion Evaluation (RACE) have developed predict occlusion at a pre-hospital level,...
Background and Purpose. Intravenous thrombolysis using tissue plasminogen activator is safe probably effective in patients >80 years old. Nevertheless, its safety has not been specifically addressed for the oldest old (≥85 old, OO). We assessed effectiveness of this group age. Methods. A prospective registry treated with intravenous thrombolysis. Patients were divided two groups (<85 Demographic data, stroke aetiology baseline National Institute Health Stroke Scale (NIHSS) score...
Introduction . Our aim was to analyze our clinical experience with dabigatran etexilate in secondary stroke prevention. Methods We retrospectively included patients starting for prevention from March 2010 December 2012. Efficacy and safety variables were registered. Results 106 included, median follow-up of 12 months (range 1–31). Fifty-six females (52.8%), mean age 76.4 50–95, SD 9.8), CHADS2 4 2–6), CHA2DS2-VASc 5 2–9), HAS-BLED 2 1–5). Indication ischemic 101 acute cerebral hemorrhage...
Fundamento.Estudiar el número de pacientes diagnosticados ictus en servicio urgencias hospitalario un hospital primer nivel y la proporción estos que finalmente eran pseudoictus, así como describir analizar las variables pueden ayudar diagnóstico diferencial los servicios hospitalarios.Método.Estudio prospectivo 9 meses.Se incluyeron todos valorados Urgencias e ingresados con ictus.Se analizaron diversas clínicas incluían historia previa, del evento actual, examen físico general neurológico...
Descompressive craniectomy (DC) for treatment of malignant infarction the middle cerebral artery (MIMCA) reduces mortality and increases probability favourable outcome.To present experience in daily practice after implantation a clinical protocol DC.Prospective register patients with MIMCA treated DC. Age, stroke severity -National Institute Health Stroke Scale (NIHSS) score-, basal characteristics, delay until DC, mortality, modified Rankin (mRS) score at three twelve months questionnaire...
To analyze the neurological attention of a county hospital recent creation, with special emphasis in health care indicators, both out-patients consultations and patients admitted to hospital.We have made descriptive analysis developed by our Neurology Section between years 2008 2013. We also comparative indicators corresponding 2012 2013 (5th 6th clinical activity) those two other hospitals similar features, three secondary level, four tertiary level.The was best number first visits divided...