A5080342838- Essential Oils and Antimicrobial Activity
- Nanoparticles: synthesis and applications
- vaccines and immunoinformatics approaches
- Probiotics and Fermented Foods
- Phytochemicals and Antioxidant Activities
- Monoclonal and Polyclonal Antibodies Research
- Bacteriophages and microbial interactions
- Fungal Biology and Applications
- Leptospirosis research and findings
- Indoor Air Quality and Microbial Exposure
- Salmonella and Campylobacter epidemiology
- Medicinal Plants and Neuroprotection
- Piperaceae Chemical and Biological Studies
- Natural Antidiabetic Agents Studies
- Ethnobotanical and Medicinal Plants Studies
- Air Quality and Health Impacts
- Viral gastroenteritis research and epidemiology
- Bee Products Chemical Analysis
- Insect and Pesticide Research
- Enzyme Production and Characterization
- Pneumonia and Respiratory Infections
- Phytochemistry and biological activity of medicinal plants
- Advanced Chemical Sensor Technologies
- Antimicrobial Peptides and Activities
- Moringa oleifera research and applications
Shaqra University
2020-2024
University of Leicester
2015
Bionanotechnology is the combination of biotechnology and nanotechnology for development biosynthetic environmentally friendly nanomaterial synthesis technology. The presented research work adopted a reliable sustainable approach to manufacturing silver nanoparticles from Brachychiton populneus (BP-AgNPs) leaf extract in aqueous medium. populneus-derived were characterized by UV–Vis spectroscopy, Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy...
In this study, the antibacterial and antifungal properties of silver nanoparticles synthesized with aqueous plant extract Acer oblongifolium leaves were defined using a simplistic, environmentally friendly, reliable, cost-effective method. The oblongifolium, which served as capping reducing agent, was used to biosynthesize nanoparticles. UV visible spectroscopy, X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), scanning electron microscopy analyze biosynthesized...
Piper nigrum is a widely used plant in traditional remedies and known for its numerous biological properties. However, fraction-based antioxidant activity their antimutagenic potential are not yet fully investigated. Different extracts of the seeds P. were obtained by sequential extraction different solvents. All evaluated antibacterial activities using methods. The most active fraction was analyzed Ames Salmonella test. against methicillin-resistant Staphylococcus aureus (MRSA) found to be...
The important role of Lactiplantibacillus plantarum strains in improving the human mucosal and systemic immunity, preventing non-steroidal anti-provocative drug-induced reduction T-regulatory cells, as probiotic starter cultures food processing has motivated in-depth molecular genomic research these strains. current study, building on this concept, reveals importance 13-3 a potential bacteriocin-producing strain that helps condition digestive system thus enhances immunity living beings via...
The demand of functional foods is on the rise, and researchers are trying to develop nutritious dairy products by using well-characterized strains bacteria. In this study, we identified locally isolated Lactobacillus fermentum from Bubalus bubalis (Nilli Ravi buffalo) milk evaluated their potential as probiotics in food like fermented milk. Fifteen were initially isolated, only four (NMCC-2, NMCC-14, NMCC-17, NMCC-27) examined for morphological biochemical characterizations due ability gas...
Providencia heimbachae, a Gram -ve, rod-shaped, and opportunistic bacteria isolated from the urine, feces, skin of humans engage in wide range infectious diseases such as urinary tract infection (UTI), gastroenteritis, bacteremia. This bacterium belongs to Enterobacteriaceae family can resist antibiotics known multidrug-resistant (MDR), be life-threatening humans. After retrieving whole proteomic sequence P. heimbachae ATCC 35613, total 6 non-homologous pathogenic proteins were separated....
Citrobacter koseri is a gram-negative rod that has been linked to infections in people with significant comorbidities and immunocompromised immune systems. It most commonly known cause urinary tract infections. Thus, the development of an efficacious C. vaccine imperative, as pathogen acquired resistance current antibiotics. Subtractive proteomics was employed during this research identify potential antigenic proteins design effective against koseri. The pipeline identified two targets:...
Microbial infections and antibiotic resistance are some of the prime factors that ascribed to endanger human health. Several reports have highlighted drug-resistant pathogens assist in etiology various chronic diseases lead fatality. The present study deciphered role zinc oxide nanoparticles (ZnO NPs) as therapeutics against selected bacterial strains. plant-based technique was followed synthesize ZnO NPs. synthesis confirmed with different techniques viz. X-ray diffraction, transmission...
In pursuit of an environmentally benign fungicide alternative, the current study explored antifungal activity Chlorella vulgaris extracts against six plant pathogenic fungi (in vitro). The well diffusion agar method was used to investigate growth inhibition Fusarium oxysporum, sp., solani, A. flavus, niger, and alternata using three C. viz. methanol (CvME), acetone (CvAE), diethyl ether (CvDE). Different concentrations CvDE were also investigated F. oxysporum. morphological modifications in...
Parthenium hysterophorus L. is a poisonous Asteraceae weed. The phytochemical profile, antioxidant activity, total phenolic contents (TPC), flavonoid (TFC), and cytotoxicity of flower extract were evaluated in this study, the toxic effects assessed rabbits. HPLC-DAD system was used for analysis. hemolytic DPPH assays performed. orally administering crude to rabbits (n = 5) at four different doses (10, 20, 40, 80 mg/kg) ten days on hematological biochemical parameters investigated. contained...
Extensively drug-resistant (XDR) Salmonella enterica serovar Typhi (S. Typhi) poses a grave threat to public health due increased mortality and morbidity caused by typhoid fever. Honey is promising antibacterial agent, we aimed determine the activity of honey against XDR S. Typhi.We isolated 20 clinical isolates from pediatric septicemic patients determined minimum inhibitory concentrations (MICs) different antibiotics pathogens using VITEK 2 Compact system. Antimicrobial-resistant genes...
Foodborne infections caused by bacterial pathogen Campylobacter jejuni (C.jejuni) are frequent throughout the globe.The primary objective of present study is to examine genetic factors responsible for virulence and antibiotic resistance in strains isolated from broilers, laying hens, farm workers.This investigation involved collection a total 300 samples farmers.The were processed conventional isolation C. confirmed through biochemical analysis PCR amplification 16S rRNA gene.The further...
The global spread of extended-spectrum beta-lactamase (ESBL)-producing and carbapenem-resistant Enterobacterales (CRE) poses a significant concern. Acquisition antimicrobial resistance genes leads to against several antibiotics, limiting treatment options. We aimed study ESBL-producing CRE transmission in clinical settings.
Mentha essential oil is one of the most utilized in food and pharmaceutical industries. The present study reports chemical composition antibacterial properties leaf oils species. Further, effect harvesting period on yield was also investigated. Firstly, cultivated piperita wild longifolia, revealed significant differences their profile. M. longifolia characterized with endo-borneol (1.12-6.2%), caryophyllene (2.72-7.03%), isopipertenone (0.07-0.36%), germacrene D (0.98-3.22%),...
Drug resistance and new diseases are becoming serious threat for flora animals. Scientists developing more effective amalgams to thwart millions of demises. Traditional medication uses Ferula spp. in being conferred this framework. We used Scientific direct, Google Scholar, PubMed, research Ferula's antimicrobial profile amongst which we found five antibacterial. Moreover, ferulenol from communis unveiled decent action. Four novel thiophene were attained foetida roots (foetithiophenes C-F...
Malaria is one of the major causes health and disability globally, even after tremendous efforts to eradicate it. Till date no highly effective vaccine available for its control. The primary reason low efficacy vaccines extensive polymorphism in potential candidate antigen genes HLA polymorphisms human population. This problem can be resolved by developing a using promiscuous peptides combine number alleles. study predicted T B cell epitopes (promiscuous peptides) targeting PPPK-DHPS DHFR-TS...
The present investigation deals with the antioxidant and antibacterial activity of chloroform methanolic extracts Lycium shawii Tetraena qatarensis leaves. Antioxidant was evaluated using DPPH FRAP assay. In assay, lowest IC50 values 45.63 46.17µg/ml were observed extract leaves, respectively. assay most showed optical density >0.5 at 40µg/ml. test, all tested found active towards bacterial strains MIC ranged between 0.03125 to 0.12mg/mL. Subsequently, in combined effect highest fold...
Leptospirosis is a febrile illness caused by the Leptospira, which highly motile, spirochete threadlike thin rod bacteria having hook-like structure on both ends. This causes nearly 58990 deaths worldwide every year. They are most commonly found in rodents and can be transferred cuts abrasions body, mucous membranes or conjunctivae, aerosol inhalation of microscopic droplets. Entry body lead to entry blood circulation, different organs will targeted. review article explains current...